Houston Astros vs Milwaukee Brewers Prediction, 5/5/2025 MLB Picks, Best Bets & Odds
Game: Houston Astros vs Milwaukee Brewers
Date: Monday, May 5, 2025
Location: American Family Field in Milwaukee, WI
TV: FanDuel Sports Network Wisconsin
Odds/Point Spread: Houston (-160) Milwaukee (+132)
The Milwaukee Brewers (16-16) are hosting the Houston Astros (16-14) at American Family Field on Monday. The line on this matchup has Houston at -160 while Milwaukee is at +132. The betting total comes in at 9. The starting pitchers are Ronel Blanco and Tobias Myers.


As a squad, the Houston Astros are scoring 3.9 runs per contest, which ranks them 20th in baseball. They have earned 117 runs and have an OBP of .310. The Astros have accounted for 38 doubles as a unit and have hit 25 baseballs out of the stadium. They have 110 runs batted in in addition to 233 hits on the campaign, while their team batting average comes in at .236. Houston has a slugging percentage of .357 and have been rung up 244 times, while drawing a walk on 98 occasions.
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They have accrued a K/BB ratio of 3.35 and their pitching staff has recorded a WHIP of 1.09. Astros pitchers have given up 29 home runs in addition to 104 runs in total (3rd in MLB). Houston has conceded 208 hits (7.0 per 9 innings) and 96 earned runs. The Astros have an earned run average of 3.23 on the year (5th in the league), and the staff has struck out 275 batters. Their pitching staff has walked 82 opposing players and their FIP is 3.43 as a unit this season.
The Astros have sent 96 relief pitchers to the hill for the season. The relief pitchers have inherited 30 runners this season with 30.0% of those runners crossed the plate. They have recorded 9 saves on the season and have blown 3 of 12 save opportunities. The Astros relief pitchers have a save percentage of 75.0% and have stepped onto the mound in 34 save situations. The relief pitchers are sitting with 22 holds for the year (8th in the league). Astros pitchers have entered the contest with runners on base 22 times and also have had 26 appearances in high leverage situations.
The Astros have converted 73.0% of balls hit into play into outs out of 2,409 innings on the field, which has them sitting 3rd in professional baseball. The Detroit Tigers have earned a total of 803 putouts this season, as well as 230 assists and 12 errors. Their fielding rate is at .989 which puts them in 7th in professional baseball, and have a total of 17 double plays.
Blanco (17-9 career record) sits with a FIP of 3.46 while he has gone up against 1,054 hitters during his time in the majors. He has allowed 194 base hits (6.9 hits per nine innings) and has 114 walks. His earned run average is 3.52 (99 earned runs allowed) and his WHIP is 1.216. Blanco has pitched in 253 frames and has earned 251 punch outs so far in his career.
Milwaukee has knocked in 27 home runs on the campaign as well as 141 RBIs. They have hit 43 two-baggers, while taking a walk 115 times and scoring 159 runs. The Milwaukee Brewers hold a team on-base percentage of .324 in addition to a batting average of .244 for the season. The Brewers hold a slugging % of .368 and they score 4.97 runs per contest (8th in MLB). They have been called out on strikes on 254 occasions (16th in MLB) and have recorded 262 hits.
The Brewers have a WHIP of 1.351 and are the owners of a FIP of 4.47 as a unit for the season. Their K/BB ratio sits at 8.10 (251 strikeouts against 126 free passes). They have a ranking of 16th in baseball as a staff in total hits conceded with 251. They have yielded 37 dingers and they give up 4.61 runs per 9 innings (21st in MLB). The Milwaukee pitching staff have relinquished 143 runs on the year while having an ERA of 4.23 (131 earned runs surrendered).
Milwaukee bullpen pitchers hold an inherited score percentage of 47.8% out of their 46 inherited base runners. Their relievers have taken the field 29 times in high leverage situations and also on 29 occasions with base runners. With 29 save situations, the Brewers have 19 holds in addition to 4 blown saves. They are currently ranked 22nd in the league with a save rate of 55.6%, and they have dispatched 113 relievers to the hill this season. Milwaukee has called on bullpen pitchers to step onto the hill in 9 save opportunities and they have earned 5 saves.
The Milwaukee Brewers have gotten 24 double plays and own a fielding percentage of .982 (25th in pro baseball). The Brewers have 240 assists, 20 errors and have earned a total of 837 putouts for the year. Out of their 2,511 innings on the field, the Brewers have a defensive efficiency of 70.8% (11th in MLB).
Myers (9-6 win-loss record in his career) holds a 3.13 ERA while allowing 8.3 hits per nine innings. His K/BB ratio is 3.07 and he has gone up against 600 opposing batters during his pro baseball career. He has given up a total of 50 ER's while earning a WHIP of 1.215 and a FIP of 3.1. During his MLB career, Myers has conceded 132 hits while he has earned 132 strikeouts in 144 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Houston (-160)
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Additional Resources:
Milwaukee Brewers - Twitter
Houston Astros - Twitter