Kansas City Royals vs Cleveland Guardians Prediction, 9/9/2025 MLB Picks, Best Bets & Odds

Game: Kansas City Royals vs Cleveland Guardians

Date: Tuesday, September 9, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Kansas City (-210) Cleveland (+172)

The Cleveland Guardians (72-70) are hosting the Kansas City Royals (73-70) at Progressive Field on Tuesday. The line on this matchup has Kansas City at -210 and Cleveland is coming in at +172. The betting total comes in at 8.5. The pitchers taking the mound will be Noah Cameron and Joey Cantillo.

The Royals have accumulated 253 two-baggers as a team and have smacked 138 balls out of the park. Kansas City has a slugging percentage of .394 and have struck out 967 times, while drawing a walk on 380 occasions. As a unit, the Kansas City Royals are earning 3.9 runs per game, which is 28th in the league. They have earned 541 RBI's in addition to 1,168 base knocks so far this year, and their batting average sits at .245. They have 551 runs and have an on-base percentage of .307.

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Their strikeout to walk ratio sits at 2.65 and the pitching staff holds a collective WHIP of 1.24. Royals pitchers have given up 145 home runs and 552 total runs (2nd in the league). Kansas City has conceded 1,155 base hits (8.2 per 9 innings) in addition to 513 earned runs. The Royals are sitting with a team ERA of 3.63 so far this year (3rd in the league), and the staff has rung up 1,122 hitters. Their pitching staff has walked 423 opposing batters and their FIP is 3.96 as a team this year.

The Royals relief pitchers have recorded a save rate of 70.5% and have entered the game in 139 save situations. The relievers have inherited 197 base runners on the year and 27.4% of those players earned a run for their team. Royals relief pitchers have entered the game with runners on 144 times in addition to having 158 appearances in high leverage situations. The Royals have dispatched 481 relief pitchers to the mound on the season. The relievers are sitting with 77 holds on the season (17th in the league). They have recorded 43 saves this year and have missed out on 18 of 61 save opportunities.

The Royals have turned 70.8% of baseballs in play into outs out of 11,448 innings, which ranks them 6th in the majors. The Houston Astros have a total of 3,816 putouts thus far, in addition to 1,260 assists and 56 errors. Their fielding rate is at .989 which is 4th in MLB, and have accumulated 112 double plays.

Cameron has taken the hill for 113 innings and has earned 88 punch outs during his career. His earned run average is 3.03 (38 earned runs allowed) and his career WHIP is 1.133. He has surrendered 92 base hits (7.3 hits per nine innings) and has had 36 free passes. Cameron (7-6 win-loss mark in his career) sits with a FIP of 2.98 while going up against 460 opposing batters in the major leagues.

Cleveland has recorded 146 home runs this year as well as 532 RBIs. They have put up 201 doubles, while walking 432 times and scoring 552 runs. The Cleveland Guardians have compiled an OBP of .295 as well as a batting average of .224 so far this year. The Guardians hold a slugging percentage of .368 and they score 3.89 runs per contest (27th in the league). They have struck out on 1,179 instances (17th in MLB) and have notched a total of 1,042 hits.

The Guardians hold a team WHIP of 1.313 in addition to having a FIP of 4.14 as a team this season. They come in at 15th in MLB as a staff in total hits relinquished with 1,170. The Cleveland pitching staff have relinquished 600 runs this season while having a team ERA of 3.91 (548 earned runs surrendered). They have earned a strikeout to walk ratio of 8.40 (1,177 strikeouts vs 486 walks). They have conceded 155 homers and they concede 4.28 runs per 9 innings (11th in MLB).

Sitting with 156 save situations, the Guardians have compiled 94 holds in addition to 18 blown saves. Cleveland has had bullpen pitchers enter the game in 59 save opportunities and they have walked away with 41 saves. Their relievers have come in 164 times in high leverage situations and also on 132 occasions with runners on. Cleveland bullpen pitchers hold an inherited score percentage of 33.5% of 185 inherited base runners. They rank 4th in baseball with a save rate of 69.5%, and they have sent 468 bullpen pitchers to the mound on the campaign.

In their 11,349 innings played, the Guardians have a defensive efficiency of 69.3% (19th in pro baseball). The Cleveland Guardians have gotten 109 double plays and have accounted for a fielding rate of .983 (27th in pro baseball). The Guardians have accrued 1,169 assists, 88 errors and have notched a total of 3,783 putouts so far this season.

Cantillo (6-7 career win-loss mark) has earned a 4.16 ERA while giving up 8.0 hits per 9 innings. He has a strikeout to walk ratio of 2.47 and he has gone up against 477 hitters so far in his MLB career. He has surrendered 51 earned runs while holding a WHIP of 1.369 and a FIP of 4.1. So far in his career, Cantillo has surrendered 98 base hits and he has 131 punch outs in 110 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Kansas City (-210)

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