Kansas City Royals vs Los Angeles Angels Prediction, 9/23/2025 MLB Picks, Best Bets & Odds

Game: Kansas City Royals vs Los Angeles Angels

Date: Tuesday, September 23, 2025

Location: Angel Stadium in Anaheim, CA

TV: FanDuel Sports Network West

Odds/Point Spread: Kansas City (-130) Los Angeles (+110)

The Kansas City Royals (78-78) are en route to Angel Stadium on Tuesday where they will compete against the Los Angeles Angels (70-86). The line on this matchup has the Royals at -130 while the Angels are at +110. The over/under comes in at 8. The starting pitchers will be Cole Ragans and Yusei Kikuchi.

Kansas City is slugging .396 and have struck out 1,045 times, while drawing a walk on 411 occasions. They have compiled 601 RBI's and 1,277 base knocks this year, and their team batting average sits at .246. The Royals have recorded 276 two-baggers as a team and have knocked 153 balls out of the stadium. They have accounted for 611 runs and hold an on-base percentage of .308. As a team, the Kansas City Royals are scoring 3.9 runs per outing, which is 28th in the league.

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They have earned a K/BB ratio of 2.62 and their pitching staff sits with a WHIP of 1.25. Royals pitchers have allowed 164 home runs and 610 total runs (4th in baseball). Kansas City has surrendered 1,257 hits (8.2 per 9 innings) in addition to 570 earned runs. The Royals have compiled a team ERA of 3.73 this season (5th in MLB), and the staff has rung up 1,204 batters. Their pitching staff has walked 460 opposing hitters and their FIP is 4.04 as a squad on the season.

The Royals relief pitchers have earned a save percentage of 69.7% and have come into the game in 149 save situations. The relief pitchers have inherited 209 base runners over the course of the season and 26.8% of them earned a run for their team. Royals relief pitchers have entered the contest with runners on base 154 times in addition to having 165 appearances in high leverage situations. The Royals have dispatched 522 relievers to the mound on the season. The bullpen have a total of 82 holds on the season (19th in baseball). They have compiled 46 saves this season and have blown 20 out of their 66 chances to get a save.

The Houston Astros have notched a total of 4,125 putouts so far this season, in addition to 1,377 assists and 59 errors. Their fielding rate sits at .989 which ranks 4th in professional baseball, and have a total of 127 double plays. The Royals have converted 70.8% of balls hit into play into outs out of 12,375 innings on the field, which has them ranked 5th in the majors.

Ragans (20-20 career record) is the owner of a FIP of 3.65 and he has gone up against 1,550 batters during his time in the major leagues. He has conceded 307 base hits (7.4 hits per nine innings) and has 142 walks. His earned run average is 3.70 (154 earned runs allowed) and he has a career WHIP of 1.200. Ragans has taken the hill for 374 innings and is sitting with 443 strikeouts in his MLB career.

Los Angeles has tallied 217 HRs for the year to go along with 632 runs batted in. They have 206 two-baggers, while walking 466 times and notching 654 runs. The Los Angeles Angels hold an OBP of .299 as well as a batting average of .226 over the course of the season. The Angels hold a slugging percentage of .399 and they score 4.22 runs per contest (25th in baseball). They have been rung up on 1,559 occasions (1st in baseball) and have totaled 1,167 base hits.

The Los Angeles pitching staff have conceded 800 runs so far this season and come in with a team ERA of 4.87 (741 earned runs yielded). They have allowed 211 long balls and they concede 5.26 runs per 9 innings (28th in baseball). The Angels have a WHIP of 1.440 and are the owners of a FIP of 4.78 as a pitching staff this season. They currently have a K/BB ratio of 8.00 (1,218 strikeouts against 599 free passes). They come in at 27th in MLB as a pitching staff in total hits relinquished with 1,373.

Sitting with 152 save situations, the Angels have compiled 79 holds and 34 blown saves. Los Angeles has had relief pitchers step onto the hill in 70 save chances and they have tallied 36 saves. Their relief pitchers have taken the field 202 times in high leverage situations in addition to 139 occasions with runners on base. Los Angeles relievers hold an inherited score percentage of 38.1% of 210 inherited base runners. They rank 30th in MLB with a save rate of 51.4%, and they have sent 533 relievers to the hill so far this year.

The Los Angeles Angels have gotten 156 double plays and have earned a fielding percentage of .983 (26th in professional baseball). The Angels have racked up 1,350 assists, 93 errors and have accumulated 4,108 putouts this year. In 12,324 innings on the diamond, the Angels have accumulated a defensive efficiency of 68.8% (25th in pro baseball).

In his pro baseball career, Kikuchi has allowed 985 base knocks while accumulating 1,005 strikeouts in 982 innings pitched. He has surrendered 489 earned runs while holding a WHIP of 1.364 and having a FIP of 4.4. He has a K/BB ratio of 2.83 and he has gone up against 4,225 batters so far in his career. Kikuchi (47-58 career record) has earned a 4.48 earned run average and has allowed 9.0 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Kansas City (-130)

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