Los Angeles Angels vs San Diego Padres Prediction, 5/14/2025 MLB Picks, Best Bets & Odds

Game: Los Angeles Angels vs San Diego Padres

Date: Wednesday, May 14, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Los Angeles (+102) San Diego (-122)

The Los Angeles Angels (17-23) are en route to Petco Park on Wednesday where they will meet the San Diego Padres (25-15). The moneyline on this game has the Angels at +102 and the Padres are sitting at -122. The over/under is set at 8.5. The pitchers who are expected to start will be Kyle Hendricks and Randy Vasquez.

As a squad, the Los Angeles Angels are scoring 3.8 runs per outing, which ranks them 23rd in the league. They are sitting with 153 runs scored while having a team on-base percentage of .276. The Angels have compiled 50 doubles as a squad and have smacked 55 balls out of the park. They have recorded 148 runs batted in in addition to 283 base knocks so far this year, while their batting average is at .216. Los Angeles has a slugging % of .387 and have been called out on strikes 393 times, while being walked on 98 occasions.

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Their K/BB ratio is 1.95 and the pitching staff sits with a WHIP of 1.49. Angels pitchers have given up 57 home runs and 214 runs (26th in baseball). Los Angeles has conceded 370 base knocks (9.5 per 9 innings) and also 200 earned runs. The Angels hold a team ERA of 5.14 over the course of the season (26th in baseball), and they have struck out 294 batters. Their pitching staff has walked 151 opposing hitters and their FIP sits at 4.94 as a team so far this season.

The Angels relievers have compiled a save rate of 56.3% and stepped onto the hill in 30 save situations. The relievers have inherited 58 base runners this year with 44.8% of them earned a run for their team. Angels bullpen pitchers have come into the game with runners on base 36 times as well as having 39 appearances in high leverage situations. The Angels have dispatched 124 relief pitchers to the hill on the campaign. The bullpen have notched 13 holds this year (28th in MLB). They have accumulated 9 saves so far this season and have missed out on 7 of 16 save opportunities.

The Angels have transformed 67.9% of balls hit into play into outs out of their 3,150 innings, which has them sitting at 26th in MLB. The Kansas City Royals have accumulated 1,050 putouts for the season, in addition to 368 assists and 25 errors. Their fielding percentage is holding at .983 which is 23rd in pro baseball, and they have turned 47 double plays.

Hendricks has taken the mound for 1,615 innings and has accounted for 1,280 strikeouts so far in his career. Hendricks (98-85 career win-loss record) sits with a FIP of 3.67 and he has faced 6,666 hitters in the major leagues. His ERA is 3.72 (668 earned runs allowed) and he has a WHIP of 1.182. He has allowed 1,531 base hits (8.5 hits per 9 innings) and has had 379 free passes.

San Diego has a total of 37 long balls this season to go along with 169 runs batted in. They have put up 62 doubles, while walking 127 times as well as scoring 185 runs. The San Diego Padres have tallied an OBP of .332 and a team batting average of .266 on the campaign. The Padres have a team slugging percentage of .403 and they earn 4.62 runs per contest (12th in MLB). They have been called out on strikes on 271 occasions (30th in baseball) and are sitting with 355 hits.

The San Diego pitching staff have relinquished 141 runs so far this season while holding an ERA of 3.37 (132 earned runs relinquished). They have yielded 37 long balls and they yield 3.60 runs per 9 innings (4th in MLB). The Padres hold a team WHIP of 1.184 with a FIP of 3.75 as a staff on the season. Their strikeout to walk ratio sits at 8.90 (348 strikeouts vs 133 walks). They rank 3rd in the league as a pitching staff in total hits surrendered with 284.

San Diego has had relief pitchers step onto the mound in 19 save opportunities and they have tallied 16 saves. They sit at 2nd in baseball with a save percentage of 84.2%, and they have dispatched 139 bullpen pitchers to the hill so far this season. Their bullpen pitchers have come in 54 times in high leverage situations and also on 34 occasions with runners on. San Diego bullpen pitchers have an inherited score percentage of 37.3% of 51 inherited runners. With 51 save situations, the Padres have 31 holds and also 3 blown saves.

Out of their 3,174 innings played, the Padres hold a defensive efficiency of 72.1% (5th in professional baseball). The San Diego Padres have turned 28 double plays and have earned a fielding percentage of .985 (15th in pro baseball). The Padres have accrued 287 assists, 20 errors and have accounted for 1,058 putouts over the course of the season.

Vasquez (8-12 career win-loss record) has a 4.21 earned run average and has conceded 9.6 hits per 9 innings. He has a strikeout to walk ratio of 1.57 and he has gone up against 770 batters in his pro baseball career. He has given up 81 ER's while holding a WHIP of 1.483 and having a FIP of 4.1. Thus far in his career, Vasquez has surrendered 185 hits while he has tallied 113 strikeouts in 173 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Los Angeles (+102)

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