Los Angeles Angels vs Seattle Mariners Prediction, 9/12/2025 MLB Picks, Best Bets & Odds

Game: Los Angeles Angels vs Seattle Mariners

Date: Friday, September 12, 2025

Location: T-Mobile Park in Seattle, WA

TV: Root Sports Northwest

Odds/Point Spread: Los Angeles (+110) Seattle (-130)

The Seattle Mariners (78-68) welcome the Los Angeles Angels (69-77) at T-Mobile Park on Friday. The moneyline on this game has Los Angeles at +110 and Seattle is priced at -130. The over/under is 9. The pitchers taking the mound are Yusei Kikuchi and Luis Castillo.

Los Angeles has a slugging percentage of .401 and have been called out on strikes 1,434 times, while taking a walk on 453 occasions. They have accumulated 605 RBI's and 1,111 hits over the course of the season, while their average at the plate is .229. The Angels have hit 199 doubles as a team and have knocked 201 balls out of the park. They have earned 627 runs and have an OBP of .304. As a team, the Los Angeles Angels are putting up 4.3 runs per outing, which has them at 20th in MLB.

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They have accumulated a K/BB ratio of 2.05 and their pitching staff holds a WHIP of 1.43. Angels pitchers have conceded 206 home runs and also 745 runs in total (27th in the league). Los Angeles has relinquished 1,292 base hits (9.0 per 9 innings) and also 690 earned runs. The Angels are sitting with a team ERA of 4.80 this season (27th in baseball), and they have rung up 1,150 hitters. They have walked 561 opposing hitters and their FIP comes in at 4.84 as a squad so far this season.

The Angels have sent 506 relievers to the mound on the year. The relief pitchers have inherited 200 runners on the season and 36.0% of them earned a run for their team. They have tallied 35 saves this season and have blown 32 of 67 chances to get a save. The Angels relievers have accumulated a save percentage of 52.2% and have entered the game in 148 save situations. The relief pitchers have notched 78 holds this season (20th in MLB). Angels relief pitchers have stepped onto the hill with runners on base 132 times in addition to having 191 appearances in high leverage situations.

The Angels have transformed 68.9% of balls hit into play into outs out of 11,637 innings, which has them ranked 25th in professional baseball. The Kansas City Royals have earned 3,879 putouts this year, in addition to 1,277 assists and 88 errors. Their fielding percentage sits at .983 which puts them in 26th in MLB, and they have turned 148 double plays.

Kikuchi (47-58 win-loss mark in his career) sits with a FIP of 4.44 while facing 4,179 hitters during his time in the majors. He has given up 976 base hits (9.1 hits per 9 innings) and has 351 free passes. His ERA is 4.51 (486 earned runs allowed) and his WHIP is 1.367. Kikuchi has pitched in 970 innings and has tallied 1,000 punch outs thus far in his career.

The Seattle Mariners have accumulated a team on-base percentage of .319 and a batting average of .243 for the year. They have been called out on strikes on 1,293 occasions (4th in the league) and have earned a total of 1,205 hits. Seattle has recorded 213 home runs so far this year to go along with 651 RBIs. The Mariners hold a slugging percentage of .415 and they score 4.66 runs per contest (11th in baseball). They have recorded 198 doubles, while walking 492 times as well as recording 680 runs.

The Seattle pitching staff have conceded 642 runs so far this season while having an ERA of 3.96 (579 earned runs surrendered). They have surrendered 173 dingers and they concede 4.39 runs per 9 innings (16th in the league). The Mariners hold a team WHIP of 1.248 and are the owners of a FIP of 4.07 as a staff this season. Their strikeout to walk ratio is 8.60 (1,253 strikeouts against 425 walks). They have a ranking of 21st in the league as a pitching staff in total hits allowed with 1,218.

Seattle has called on relievers to take the mound in 61 save opportunities and they have recorded 38 saves. They rank 18th in MLB with a save percentage of 62.3%, and they have sent 494 relievers to the mound this season. Their relievers have taken the field 196 times in high leverage situations in addition to 119 occasions with runners on base. Seattle relievers hold an inherited score rate of 25.0% out of their 132 inherited base runners. Sitting with 143 save situations, the Mariners have compiled 82 holds and also 23 blown saves.

In 11,850 innings on the field, the Mariners have accumulated a efficiency on defense of 70.2% (12th in MLB). The Seattle Mariners have turned 107 double plays and have notched a fielding percentage of .988 (7th in baseball). The Mariners have 1,228 assists, 62 errors and have a tally of 3,950 putouts this year.

In his pro baseball career, Castillo has given up 1,201 base hits while earning 1,475 punch outs in 1,391 innings. Castillo (82-84 win-loss mark in his career) holds a 3.59 ERA while conceding 7.8 hits per nine innings. He has allowed a total of 555 earned runs while earning a WHIP of 1.188 and a FIP of 3.5. His strikeout to walk ratio is 3.27 and he has faced 5,757 hitters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Seattle (-130)

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