Los Angeles Dodgers vs Arizona Diamondbacks Prediction, 9/24/2025 MLB Picks, Best Bets & Odds

Game: Los Angeles Dodgers vs Arizona Diamondbacks

Date: Wednesday, September 24, 2025

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: Los Angeles (-150) Arizona (+125)

The Arizona Diamondbacks (79-77) will compete against the Los Angeles Dodgers (88-68) at Chase Field on Wednesday. The moneyline on this contest has Los Angeles at -150 and Arizona opens at +125. The total comes in at 8.5. The pitchers who are expected to start will be Blake Snell and Ryne Nelson.

The Dodgers have earned 249 doubles as a unit and have smacked 232 baseballs out of the stadium. Los Angeles is slugging .440 and have been called out on strikes 1,294 times, while drawing a walk on 565 occasions. As a unit, the Los Angeles Dodgers are notching 5.1 runs per contest, which is 2nd in baseball. They have 761 runs batted in in addition to 1,336 base knocks so far this year, while their team batting average is at .254. They have earned 794 runs while holding a team on-base percentage of .329.

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The Dodgers have compiled a team ERA of 4.02 on the year (18th in baseball), and the staff has struck out 1,433 batters. Dodgers pitchers have conceded 173 home runs and also 668 total runs (14th in MLB). They have walked 546 opposing batters and their FIP comes in at 4.02 as a squad so far this year. Los Angeles has given up 1,206 base knocks (7.8 per 9 innings) as well as 619 earned runs. They have accrued a K/BB ratio of 2.62 and the pitching staff holds a WHIP of 1.26.

Dodgers relief pitchers have entered the game with opponents on base 143 times and also have had 172 appearances in high leverage situations. The relievers have accumulated 120 holds on the campaign (1st in baseball). The Dodgers relievers have compiled a save rate of 62.7% and have entered the game in 192 save situations. They have accumulated 42 saves on the campaign and have blown 25 out of their 67 save chances. The relief pitchers have inherited 223 runners so far this year with 25.6% of them ended up scoring. The Dodgers have sent 555 relievers to the mound for the year.

The Dodgers have turned 70.5% of baseballs in play into outs out of their 12,468 innings, which has them sitting 11th in MLB. The Los Angeles Angels have accumulated 4,156 putouts so far this season, as well as 1,299 assists and 66 errors. Their fielding percentage is holding at .988 which is 6th in baseball, and have accumulated 99 double plays.

Snell (81-62 career record) holds a FIP of 3.11 while he has gone up against 4,768 batters in the major leagues. He has allowed 886 base hits (6.9 hits per nine innings) with 520 walks. His ERA is 3.16 (404 ER's allowed) and his career WHIP is 1.221. Snell has taken the ball for 1,151 innings and has 1,435 K's in his career.

The Arizona Diamondbacks have tallied a team OBP of .325 as well as a batting average of .252 so far this season. They have been called out on strikes on 1,252 occasions (23rd in the league) and have recorded 1,330 base hits. Arizona has tallied 209 home runs on the year as well as 752 RBIs. The Diamondbacks have a team slugging % of .435 and they earn 4.96 runs per outing (4th in the league). They have 268 doubles, while getting a free base 520 times and racking up 773 runs.

The Diamondbacks hold a team WHIP of 1.314 in addition to having a FIP of 4.25 as a pitching staff on the campaign. They currently have a strikeout to walk ratio of 8.00 (1,235 strikeouts vs 482 walks). They are sitting at 24th in the league as a staff in total hits surrendered with 1,346. They have conceded 184 long balls and they yield 4.81 runs per 9 innings (23rd in MLB). The Arizona pitching staff have given up 744 runs on the year while having a team ERA of 4.43 (685 earned runs allowed).

Arizona has had bullpen pitchers take the mound in 71 save chances and they have tallied 42 saves. They rank 22nd in the league holding a save percentage of 59.2%, and they have dispatched 480 relievers to the hill on the year. Their relief pitchers have come in 162 times in high leverage situations in addition to 144 occasions with runners on. Arizona bullpen pitchers have an inherited score percentage of 33.5% out of their 191 inherited runners. With 164 save situations, the Diamondbacks have compiled 88 holds in addition to 29 blown saves.

Out of their 12,519 innings on the field, the Diamondbacks have accumulated a defensive efficiency of 69.6% (20th in the majors). The Arizona Diamondbacks have turned 124 double plays and have earned a fielding percentage of .986 (16th in the majors). The Diamondbacks have 1,398 assists, 79 errors and have a tally of 4,173 putouts during this campaign.

Nelson (26-18 career record) has a 4.18 ERA while giving up 8.6 hits per nine innings. His strikeout to walk ratio is 2.84 and he has gone up against 1,912 batters in his MLB career. He has surrendered a total of 214 ER's while holding a WHIP of 1.230 and having a FIP of 4.1. So far in his MLB career, Nelson has allowed 440 hits while accumulating 361 strikeouts in 461 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Arizona (+125)

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