Los Angeles Dodgers vs San Diego Padres Prediction, 8/22/2025 MLB Picks, Best Bets & Odds

Game: Los Angeles Dodgers vs San Diego Padres

Date: Friday, August 22, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Los Angeles (-182) San Diego (+150)

The San Diego Padres (71-56) welcome the Los Angeles Dodgers (72-55) at Petco Park on Friday. The odds on this game have Los Angeles at -182 and San Diego is priced at +150. The total is 8. The starting pitchers are Blake Snell and Yu Darvish.

Los Angeles is slugging .438 and have been called out on strikes 1,065 times, while taking a walk on 464 occasions. They have accrued 620 RBI's and 1,071 base knocks on the campaign, while their team batting average sits at .253. The Dodgers have tallied 198 two-baggers as a team and have knocked 185 balls out of the park. They have a total of 643 runs scored while holding a team on-base percentage of .330. As a team, the Los Angeles Dodgers are scoring 5.1 runs per outing, which ranks them 2nd in MLB.

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The Dodgers have compiled a team ERA of 4.12 on the season (18th in baseball), and the staff has rung up 1,109 batters. Dodgers pitchers have surrendered 149 home runs in addition to 556 total runs (19th in baseball). They have walked 430 opposing hitters and their FIP comes in at 4.18 as a team for the season. Los Angeles has surrendered 1,020 base knocks (8.3 per 9 innings) and 509 earned runs. They have earned a K/BB ratio of 2.58 and the pitching staff has earned a collective WHIP of 1.30.

Dodgers bullpen pitchers have entered the contest with players on base 118 times as well as having 144 appearances in high leverage situations. The relief pitchers have accumulated 100 holds for the season (1st in the league). The Dodgers relief pitchers have compiled a save rate of 63.2% and have entered the game in 161 save situations. They have earned 36 saves for the year and have blown 21 of their 57 chances to get a save. The relievers have inherited 187 runners on the campaign with 25.1% of those players ended up crossing the plate. The Dodgers have dispatched 452 relievers to the hill for the season.

The Los Angeles Angels have amassed 3,335 putouts this season, in addition to 1,070 assists and 56 errors. Their fielding percentage is holding at .987 which has them sitting 8th in MLB, and they have turned 84 double plays. The Dodgers have converted 69.8% of balls in play into outs out of 10,005 innings, which ranks them 16th in professional baseball.

Snell has taken the mound for 1,121 innings and is sitting with 1,393 strikeouts in his MLB career. His ERA is 3.16 (394 ER's allowed) and he has a career WHIP of 1.223. He has surrendered 863 base hits (6.9 hits per nine innings) with 508 free passes. Snell (79-59 win-loss mark in his career) sits with a FIP of 3.12 while he has faced 4,646 opposing hitters in the majors.

The Padres have a team slugging % of .383 and they are earning 4.14 runs per outing (23rd in the league). They have hit 200 doubles, while walking 406 times as well as notching 518 runs. San Diego has hit 106 home runs so far this season to go along with 485 RBIs. They have struck out on 871 instances (28th in baseball) and have recorded 1,049 hits. The San Diego Padres have an OBP of .321 and a batting average of .251 this year.

The Padres hold a team WHIP of 1.207 in addition to having a FIP of 3.89 as a pitching staff for the season. They currently have a K/BB ratio of 8.70 (1,074 strikeouts vs 411 walks). They are sitting at 1st in MLB as a pitching staff in total hits allowed with 923. They have conceded 124 long balls and they give up 3.87 runs per 9 innings (3rd in baseball). The San Diego pitching staff have allowed 475 runs on the campaign while holding an ERA of 3.58 (439 earned runs surrendered).

San Diego relief pitchers have an inherited score rate of 27.5% of 207 inherited runners. Their relievers have come in 172 times in high leverage situations and on 146 occasions with base runners. With 143 save situations, the Padres have tallied 84 holds and 15 blown saves. They are ranked 2nd in MLB with a save percentage of 72.7%, and they have sent 439 bullpen pitchers onto the field on the campaign. San Diego has had bullpen pitchers enter the contest in 55 save chances and they have tallied 40 saves.

The San Diego Padres have gotten 94 double plays and have accounted for a fielding rate of .987 (13th in MLB). The Padres have 948 assists, 57 errors and have accumulated 3,315 putouts this season. In 9,945 innings on the diamond, the Padres have earned a defensive efficiency of 71.6% (2nd in pro baseball).

In his MLB career, Darvish has conceded 1,427 hits and he has 2,041 K's in 1,743 frames. He has conceded a total of 703 ER's while holding a WHIP of 1.138 and having a FIP of 3.6. He has a K/BB ratio of 3.66 and he has faced 7,166 batters in his pro baseball career. Darvish (112-91 win-loss record in his career) has a 3.63 ERA while giving up 7.4 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (+150)

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