Miami Marlins vs San Diego Padres Prediction, 5/26/2025 MLB Picks, Best Bets & Odds

Game: Miami Marlins vs San Diego Padres

Date: Monday, May 26, 2025

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Miami (+132) San Diego (-160)

The Miami Marlins (19-29) are traveling to Petco Park on Monday where they will play the San Diego Padres (27-21). The odds on this game have the Marlins at +132 while the Padres are at -160. The over/under has been set at 9. The expected starting pitchers are Ryan Weathers and Randy Vasquez.

Miami is slugging .387 and have been called out on strikes 404 times, while being walked on 145 occasions. They have recorded 189 runs batted in as well as 403 base knocks on the year, while their batting average is .247. The Marlins have recorded 78 two-baggers as a team and have hit 45 baseballs out of the park. They have tallied 197 runs while holding a team OBP of .311. As a team, the Miami Marlins are notching 4.1 runs per contest, which ranks them 20th in baseball.

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The Marlins have a team earned run average of 5.46 so far this season (29th in the league), and they have rung up 379 hitters. Marlins pitchers have surrendered 61 home runs and 276 runs in total (28th in baseball). Their pitching staff has walked 188 opposing players and their FIP comes in at 4.61 as a unit on the year. Miami has relinquished 445 base hits (9.4 per 9 innings) and also 259 earned runs. They have a strikeout to walk ratio of 2.02 and their pitching staff holds a WHIP of 1.49.

Marlins pitchers have stepped onto the hill with opponents on base 48 times as well as having 55 appearances in high leverage situations. The relievers have 23 holds on the campaign (28th in baseball). The Marlins relievers have a save percentage of 46.7% and have stepped onto the mound in 38 save situations. They have compiled 7 saves on the season and have not converted 8 of their 15 chances to get a save. The relievers have inherited 68 runners over the course of the season and 36.8% of those runners crossed the plate. The Marlins have sent 164 relief pitchers to the mound so far this season.

The Marlins have converted 68.0% of balls hit into play into outs out of their 3,840 innings on the field, which has them sitting 24th in baseball. The Los Angeles Dodgers have accumulated 1,280 putouts over the course of the season, as well as 423 assists and 24 errors. Their fielding rate sits at .986 which has them sitting 15th in professional baseball, and have accumulated 34 double plays.

Weathers (11-21 career win-loss mark) has earned a FIP of 4.89 while he has gone up against 1,083 opposing hitters during his time in the majors. He has given up 260 base hits (9.3 hits per 9 innings) and has 88 free passes. His earned run average is 4.96 (139 earned runs allowed) and his career WHIP is 1.380. Weathers has pitched in 252 innings and has accumulated 207 punch outs during his MLB career.

The Padres hold a team slugging percentage of .389 and they average 4.27 runs per contest (16th in the league). They have notched 70 two-baggers, while taking a walk 149 times and earning 205 runs. San Diego has a total of 43 home runs on the season to go along with 187 runs batted in. They have been called out on strikes on 337 instances (30th in MLB) and have accounted for 409 base hits. The San Diego Padres hold an on-base percentage of .321 and a team batting average of .256 for the season.

The Padres hold a team WHIP of 1.196 in addition to having a FIP of 3.88 as a staff so far this year. Their strikeout to walk ratio comes in at 8.90 (419 strikeouts vs 159 bases on balls). They have a ranking of 3rd in the league as a pitching staff in total hits given up with 348. They have allowed 50 dingers and they give up 3.93 runs per 9 innings (10th in the league). The San Diego pitching staff have conceded 185 runs on the year and come in with a team ERA of 3.50 (165 earned runs surrendered).

Sitting with 56 save situations, the Padres have amassed 33 holds in addition to 6 blown saves. San Diego has had relief pitchers step onto the mound in 22 save opportunities and they have come away with 16 saves. Their relief pitchers have stepped onto the mound 60 times in high leverage situations and on 47 occasions with base runners. San Diego bullpen pitchers have an inherited score percentage of 37.9% of 66 inherited runners. They rank 3rd in baseball with a save percentage of 72.7%, and they have dispatched 166 relievers to the mound so far this season.

The San Diego Padres have gotten 35 double plays and have a fielding percentage of .984 (23rd in professional baseball). The Padres have 351 assists, 27 errors and have accumulated 1,272 putouts this year. In 3,816 innings played, the Padres have earned a defensive efficiency of 71.9% (5th in professional baseball).

Thus far in his career, Vasquez has allowed 193 base knocks while tallying 122 punch outs in 184 innings pitched. He has surrendered 84 ER's while earning a WHIP of 1.444 and being the owner of a FIP of 4.0. His K/BB ratio is 1.67 and he has gone up against 812 batters during his career. Vasquez (9-13 career record) has earned a 4.10 ERA while allowing 9.4 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-160)

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