Minnesota Twins vs Cleveland Guardians Prediction, 4/29/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Cleveland Guardians

Date: Tuesday, April 29, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Minnesota (+110) Cleveland (-130)

The Minnesota Twins (12-16) are en route to Progressive Field on Tuesday where they will try to defeat the Cleveland Guardians (15-12). The moneyline on this game has the Twins at +110 and the Guardians are priced at -130. The betting total is set at 8. The pitchers taking the mound will be Chris Paddack and Tanner Bibee.

Minnesota is slugging .360 and have been called out on strikes 228 times, while taking a walk on 86 occasions. They have earned 101 runs batted in as well as 206 hits this year, while their batting average comes in at .226. The Twins have tallied 51 doubles as a squad and have hit 21 balls out of the park. They have earned a total of 106 runs scored while holding a team on-base percentage of .305. As a team, the Minnesota Twins are knocking in 3.8 runs per game, which ranks them 21st in baseball.

Get all of our MLB Parlay Picks

The Twins have compiled a team earned run average of 3.64 this season (10th in the league), and they have struck out 247 batters. Twins pitchers have allowed 30 home runs and 108 runs in total (9th in baseball). Their pitching staff has walked 73 players from the other team and their FIP sits at 3.71 as a team this year. Minnesota has relinquished 221 hits (8.2 per 9 innings) and also 98 earned runs. They have accumulated a K/BB ratio of 3.38 and their pitching staff holds a collective WHIP of 1.21.

Twins relief pitchers have entered the game with opponents on base 21 times in addition to having 23 appearances in high leverage situations. The relievers have a total of 22 holds this year (6th in baseball). The Twins relievers have earned a save percentage of 37.5% and stepped onto the hill in 31 save situations. They have tallied 3 saves so far this year and have blown 5 of 8 chances to get a save. The relief pitchers have inherited 33 base runners on the campaign with 39.4% of them ended up crossing the plate. The Twins have sent 95 relievers to the hill this season.

The Twins have transformed 69.2% of balls in play into outs out of their 2,178 innings on the diamond, which has them sitting at 20th in pro baseball. The Milwaukee Brewers have notched a total of 726 putouts over the course of the season, in addition to 181 assists and 18 errors. Their fielding rate is currently at .981 which ranks 25th in baseball, and they have turned 15 double plays.

Paddack (27-27 win-loss mark in his career) is the owner of a FIP of 4.42 and he has faced 1,875 opposing hitters during his time in the major leagues. He has conceded 438 hits (8.9 hits per nine innings) and has 102 free passes. His earned run average is 4.49 (222 earned runs allowed) and his WHIP is 1.213. Paddack has taken the mound for 445 innings and is sitting with 437 K's during his MLB career.

The Guardians have a team slugging percentage of .386 and they score 3.96 runs per game (20th in the league). They have put up 36 two-baggers, while taking a walk 85 times as well as recording 107 runs. Cleveland has tallied 30 long balls over the course of the season and 101 RBIs. They have struck out on 215 occasions (23rd in baseball) and have totaled 208 hits. The Cleveland Guardians have earned an OBP of .308 in addition to a batting average of .237 on the season.

The Guardians have a WHIP of 1.426 and have a FIP of 4.38 as a unit over the course of the season. Their strikeout to walk ratio comes in at 8.80 (232 strikeouts against 106 bases on balls). They are currently ranked 19th in the league as a pitching staff in total hits allowed with 232. They have allowed 34 long balls and they relinquish 4.75 runs per 9 innings (22nd in baseball). The Cleveland pitching staff have given up 125 runs so far this year and come in with a team ERA of 4.37 (115 earned runs relinquished).

Sitting with 40 save situations, the Guardians have earned 28 holds in addition to 3 blown saves. Cleveland has called on bullpen pitchers to step onto the hill in 12 save opportunities and they have earned 9 saves. Their relief pitchers have stepped onto the hill 24 times in high leverage situations and on 24 occasions with runners on. Cleveland relievers hold an inherited score percentage of 20.6% of 34 inherited runners. They rank 4th in MLB with a save rate of 75.0%, and they have dispatched 93 relief pitchers to the hill over the course of the season.

The Cleveland Guardians have gotten 25 double plays and own a fielding percentage of .981 (23rd in baseball). The Guardians have recorded 206 assists, 18 errors and are sitting with 711 putouts over the course of the season. In their 2,133 innings played, the Guardians are sitting with a efficiency on defense of 67.7% (26th in MLB).

So far in his career, Bibee has surrendered 296 base knocks while he has accumulated 348 punch outs in 341 frames. Bibee (24-14 win-loss mark in his career) is the owner of a 3.40 earned run average while surrendering 7.8 hits per nine innings. He has surrendered 129 ER's while earning a WHIP of 1.169 and a FIP of 3.4. He has a strikeout to walk ratio of 3.38 and he has gone up against 1,406 opposing batters thus far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Cleveland (-130) and under 8 runs

Get $60 worth of FREE premium member picks. No Obligation. No Salesman. No Credit Card. Fast Sign up with Instant Access Click Here