Minnesota Twins vs Cleveland Guardians Prediction, 8/1/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Cleveland Guardians

Date: Friday, August 1, 2025

Location: Progressive Field in Cleveland, OH

TV: CLEGuardians.TV

Odds/Point Spread: Minnesota (+220) Cleveland (-275)

Progressive Field is the site where the Cleveland Guardians (54-54) will take on the Minnesota Twins (51-57) on Friday. The odds on this game have Minnesota at +220 and Cleveland opens at -275. The over/under comes in at 9. The starting pitchers will be Joe Ryan and Gavin Williams.

The Twins have hit 168 doubles as a squad and have smacked 125 balls out of the stadium. Minnesota has a slugging percentage of .399 and have been rung up 884 times, while drawing a walk on 322 occasions. As a squad, the Minnesota Twins are putting up 4.2 runs per game, which ranks them 21st in the league. They have accrued 432 RBI's and 870 hits so far this season, while their team batting average sits at .241. They have notched a total of 451 runs scored while having a team OBP of .313.

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They have a K/BB ratio of 3.26 and their pitching staff holds a WHIP of 1.27. Twins pitchers have surrendered 121 long balls and 484 runs (20th in the league). Minnesota has conceded 923 base hits (8.8 per 9 innings) in addition to 452 earned runs. The Twins have compiled a team ERA of 4.29 on the year (23rd in baseball), and their staff has rung up 919 batters. Their pitching staff has walked 282 opposing batters and their FIP is 3.85 as a team for the season.

The Twins bullpen have a save percentage of 57.1% and have entered the game in 110 save situations. The bullpen pitchers have inherited 110 base runners this year with 36.4% of those players crossed home plate. Twins pitchers have stepped onto the hill with runners on 77 times and also have had 130 appearances in high leverage situations. The Twins have sent 373 relief pitchers to the hill this year. The relievers have 73 holds on the year (6th in baseball). They have recorded 20 saves for the season and have missed out on 15 out of their 35 chances to get a save.

The Milwaukee Brewers are sitting with 2,843 putouts for the season, in addition to 797 assists and 52 errors. Their fielding percentage is holding steady at .986 which is 16th in baseball, and have a total of 55 double plays. The Twins have transformed 68.7% of balls in play into outs out of their 8,529 innings on the diamond, ranking them 26th in pro baseball.

Ryan has pitched in 591 innings and has totaled 662 strikeouts so far in his MLB career. His earned run average is 3.70 (243 ER's allowed) and his WHIP is 1.044. He has given up 484 base hits (7.4 hits per 9 innings) and has had 133 free passes. Ryan (43-31 career mark) has earned a FIP of 3.64 while he has faced 2,388 hitters during his time in the major leagues.

The Guardians hold a slugging percentage of .377 and they score 3.93 runs per game (26th in the league). They have notched 162 doubles, while taking a walk 350 times and racking up 424 runs. Cleveland has a total of 114 HRs over the course of the season to go along with 408 RBIs. They have been rung up on 883 occasions (18th in the league) and have a total of 805 hits. The Cleveland Guardians have compiled an OBP of .301 in addition to a batting average of .228 this year.

The Guardians have a team WHIP of 1.312 in addition to having a FIP of 4.14 as a squad for the year. They are currently ranked 12th in MLB as a staff in total hits allowed with 875. The Cleveland pitching staff have given up 453 runs over the course of the season while holding a team ERA of 3.90 (416 earned runs surrendered). Their K/BB ratio sits at 8.40 (899 strikeouts against 383 walks). They have conceded 119 home runs and they concede 4.25 runs per 9 innings (13th in the league).

With 123 save situations, the Guardians have amassed 76 holds and 14 blown saves. Cleveland has called on relief pitchers to step onto the hill in 44 save chances and they have earned 30 saves. Their bullpen pitchers have taken the field 121 times in high leverage situations and also on 92 occasions with runners on. Cleveland relief pitchers hold an inherited score percentage of 36.7% of 128 inherited runners. They are currently ranked 7th in MLB holding a save rate of 68.2%, and they have dispatched 360 relief pitchers to the hill on the year.

The Cleveland Guardians have turned 85 double plays and hold a fielding percentage of .982 (28th in professional baseball). The Guardians have racked up 891 assists, 70 errors and have earned a total of 2,879 putouts on the season. Out of their 8,637 innings on the diamond, the Guardians have earned a efficiency on defense of 69.6% (19th in professional baseball).

Williams (12-19 mark in his career) has a 3.83 earned run average while conceding 7.7 hits per 9 innings. He has a K/BB ratio of 2.09 and he has gone up against 1,148 opposing batters so far in his MLB career. He has surrendered 114 ER's while holding a WHIP of 1.335 and having a FIP of 3.8. So far in his career, Williams has allowed 229 hits and he has 269 strikeouts in 268 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Minnesota (+220)

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