Minnesota Twins vs Kansas City Royals Prediction, 9/6/2025 MLB Picks, Best Bets & Odds

Game: Minnesota Twins vs Kansas City Royals

Date: Saturday, September 6, 2025

Location: Kauffman Stadium in Kansas City, MO

TV: FanDuel Sports Network Kansas City

Odds/Point Spread: Minnesota (+172) Kansas City (-210)

The Minnesota Twins (62-77) are hitting the road to Kauffman Stadium on Saturday where they will attempt to beat the Kansas City Royals (70-69). The odds on this game have the Twins at +172 while the Royals are coming in at -210. The betting total comes in at 8.5. The pitchers taking the mound will be Pablo Lopez and Seth Lugo.

As a team, the Minnesota Twins are compiling 4.2 runs per game, which puts them at 25th in MLB. They have tallied 584 runs while holding a team on-base percentage of .311. The Twins have tallied 213 doubles as a team and have hit 163 balls out of the park. They have amassed 555 RBI's in addition to 1,109 base knocks this season, while their average at the plate is sitting at .238. Minnesota has a slugging rate of .397 and have struck out 1,151 times, while drawing a walk on 427 occasions.

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They have earned a strikeout to walk ratio of 2.98 and the pitching staff has a collective WHIP of 1.32. Twins pitchers have surrendered 169 long balls and also 658 runs in total (23rd in the league). Minnesota has conceded 1,223 base hits (9.0 per 9 innings) as well as 613 earned runs. The Twins have a team ERA of 4.51 on the year (24th in baseball), and their staff has struck out 1,167 hitters. Their pitching staff has walked 392 opposing batters and their FIP is 4.13 as a unit so far this season.

Twins relief pitchers have entered the contest with runners on base 103 times in addition to having 159 appearances in high leverage situations. The relief pitchers have earned 84 holds on the year (10th in MLB). The Twins relievers have earned a save percentage of 54.2% and stepped onto the hill in 134 save situations. They have accumulated 26 saves for the year and have blown 22 out of their 48 save chances. The relievers have inherited 148 base runners over the course of the season with 37.8% of them earned a run for their team. The Twins have dispatched 472 relief pitchers to the mound over the course of the season.

The Milwaukee Brewers have a total of 3,672 putouts at this point in the season, in addition to 1,034 assists and 68 errors. Their fielding rate is holding at .986 which is 16th in pro baseball, and they have turned 85 double plays. The Twins have transformed 68.4% of baseballs in play into outs out of their 11,016 innings on the diamond, which ranks them 27th in baseball.

Lopez has taken the mound for 949 innings and has earned 982 punch outs thus far in his career. His earned run average is 3.84 (405 earned runs allowed) and his WHIP is 1.175. He has allowed 870 hits (8.2 hits per nine innings) and has 245 free passes. Lopez (59-52 win-loss mark in his career) sits with a FIP of 3.78 and he has faced 3,930 batters in the majors.

Kansas City has compiled 132 home runs so far this year as well as 523 runs batted in. They have notched 244 doubles, while getting a free base 365 times as well as recording 533 runs. The Kansas City Royals have a team on-base percentage of .306 as well as a batting average of .245 this year. The Royals have a team slugging percentage of .392 and they tally 3.83 runs per contest (28th in the league). They have been rung up on 945 occasions (30th in the league) and have accounted for 1,137 hits.

The Royals are sitting with a team WHIP of 1.244 in addition to having a FIP of 3.97 as a staff for the season. They are currently ranked 10th in MLB as a staff in total hits surrendered with 1,128. The Kansas City pitching staff have allowed 541 runs on the year while having an ERA of 3.66 (502 earned runs relinquished). Their K/BB ratio sits at 7.90 (1,086 strikeouts vs 409 bases on balls). They have conceded 142 dingers and they surrender 3.94 runs per 9 innings (2nd in MLB).

Kansas City has had bullpen pitchers enter the contest in 59 save opportunities and they have tallied 41 saves. They rank 4th in MLB with a save percentage of 69.5%, and they have sent 466 relievers onto the field this season. Their relief pitchers have stepped onto the hill 151 times in high leverage situations and on 139 occasions with runners on. Kansas City bullpen pitchers have an inherited score rate of 27.9% out of 190 inherited base runners. With 133 save situations, the Royals have accumulated 73 holds in addition to 18 blown saves.

In 11,124 innings played, the Royals hold a defensive efficiency of 70.8% (7th in baseball). The Kansas City Royals have gotten 107 double plays and have accounted for a fielding rate of .989 (4th in pro baseball). The Royals have accrued 1,228 assists, 56 errors and have earned a total of 3,708 putouts so far this season.

During his MLB career, Lugo has allowed 889 base knocks and he has 954 punch outs in 992 frames. He has allowed a total of 385 ER's while earning a WHIP of 1.174 and a FIP of 3.4. His K/BB ratio is 3.46 and he has faced 4,098 batters in his career. Lugo (64-47 career record) holds a 3.49 earned run average while giving up 8.1 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Minnesota (+172)

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