Minnesota Twins vs Los Angeles Angels Prediction, 9/10/2025 MLB Picks, Best Bets & Odds
Game: Minnesota Twins vs Los Angeles Angels
Date: Wednesday, September 10, 2025
Location: Angel Stadium in Anaheim, CA
TV: FanDuel Sports Network West
Odds/Point Spread: Minnesota (+110) Los Angeles (-132)
Angel Stadium is where the Los Angeles Angels (67-77) will go up against the Minnesota Twins (64-80) on Wednesday. The odds on this game have the Twins at +110 while the Angels are priced at -132. The betting total is set at 8.5. The pitchers taking the mound will be Taj Bradley and Jose Soriano.


Minnesota is slugging .398 and have struck out 1,197 times, while drawing a walk on 445 occasions. They have tallied 580 runs batted in as well as 1,157 base knocks this season, and their batting average is sitting at .239. The Twins have hit 220 doubles as a unit and have knocked 170 balls out of the park. They have notched a total of 612 runs and hold an on-base percentage of .312. As a team, the Minnesota Twins are putting up 4.3 runs per outing, which ranks them 23rd in MLB.
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They have a strikeout to walk ratio of 2.95 and the pitching staff has a collective WHIP of 1.33. Twins pitchers have surrendered 173 long balls and also 686 runs in total (23rd in baseball). Minnesota has conceded 1,269 base hits (9.0 per 9 innings) and also 640 earned runs. The Twins hold a team earned run average of 4.55 this season (24th in MLB), and the staff has struck out 1,209 batters. They have walked 410 opposing batters and their FIP comes in at 4.13 as a team this year.
The Twins have dispatched 488 relief pitchers to the mound over the course of the season. The relief pitchers have inherited 157 runners this season with 36.3% of those runners ended up scoring. They have earned 27 saves on the campaign and have blown 23 of their 50 chances to save the game. The Twins relief pitchers have earned a save rate of 54.0% and have stepped onto the mound in 139 save situations. The relievers are sitting with 87 holds this season (10th in the league). Twins pitchers have entered the game with runners on 108 times in addition to having 161 appearances in high leverage situations.
The Twins have turned 68.3% of balls hit into play into outs out of their 11,403 innings, which ranks them 29th in professional baseball. The Milwaukee Brewers have accumulated 3,801 putouts over the course of the season, as well as 1,079 assists and 73 errors. Their fielding percentage is holding steady at .985 which has them ranked 18th in MLB, and have earned 88 double plays.
Bradley has taken the hill for 368 innings and has totaled 392 K's so far in his MLB career. His ERA is 4.81 (197 earned runs allowed) and his WHIP is 1.303. He has surrendered 345 base knocks (8.4 hits per 9 innings) and has had 135 walks. Bradley (19-26 career mark) has earned a FIP of 4.74 while facing 1,575 opposing batters in the major leagues.
The Los Angeles Angels have compiled an OBP of .303 as well as a batting average of .227 this season. They have been called out on strikes on 1,422 occasions (1st in the league) and have 1,089 base hits. Los Angeles has accumulated 198 home runs on the campaign to go along with 590 RBIs. The Angels hold a slugging percentage of .399 and they are earning 4.24 runs per contest (24th in the league). They have hit 198 two-baggers, while taking a walk 448 times and racking up 611 runs.
The Los Angeles pitching staff have allowed 740 runs on the year while holding a team ERA of 4.84 (685 earned runs relinquished). They have conceded 203 long balls and they yield 5.22 runs per 9 innings (28th in baseball). The Angels have a team WHIP of 1.438 and have a FIP of 4.84 as a team for the season. Their strikeout to walk ratio comes in at 8.00 (1,130 strikeouts vs 553 free passes). They are sitting at 27th in baseball as a pitching staff in total hits given up with 1,280.
Los Angeles relievers hold an inherited score percentage of 36.2% out of their 199 inherited runners. Their bullpen pitchers have stepped onto the hill 187 times in high leverage situations and on 131 occasions with runners on. With 146 save situations, the Angels have accrued 78 holds in addition to 31 blown saves. They are currently ranked 28th in baseball holding a save percentage of 52.3%, and they have sent 498 relief pitchers to the hill on the campaign. Los Angeles has had relief pitchers step onto the hill in 65 save opportunities and they have earned 34 saves.
The Los Angeles Angels have gotten 146 double plays and hold a fielding percentage of .984 (26th in the majors). The Angels have racked up 1,260 assists, 85 errors and have notched a total of 3,825 putouts on the campaign. In 11,475 innings on the diamond, the Angels hold a defensive efficiency of 68.9% (25th in baseball).
During his career, Soriano has allowed 275 base knocks while accumulating 301 K's in 318 frames. Soriano (17-20 career record) has earned a 3.79 earned run average while conceding 7.8 hits per 9 innings. He has given up a total of 134 ER's while earning a WHIP of 1.307 and a FIP of 3.7. His strikeout to walk ratio is 2.13 and he has faced 1,348 opposing batters during his career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Minnesota (+110)
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Additional Resources:
Los Angeles Angels - Twitter
Minnesota Twins - Twitter