New York Mets vs Chicago Cubs Prediction, 9/24/2025 MLB Picks, Best Bets & Odds

Game: New York Mets vs Chicago Cubs

Date: Wednesday, September 24, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: New York (+126) Chicago (-152)

The Chicago Cubs (88-68) will go up against the New York Mets (80-76) at Wrigley Field on Wednesday. The moneyline on this contest has New York at +126 and Chicago is coming in at -152. The betting total is set at 8. The starting pitchers will be Jonah Tong and Matthew Boyd.

New York is slugging .429 and have struck out 1,274 times, while drawing a walk on 542 occasions. They have recorded 720 runs batted in as well as 1,315 hits on the campaign, while their batting average is .250. The Mets have tallied 255 two-baggers as a squad and have knocked 215 balls out of the park. They have tallied 739 runs scored while holding a team on-base percentage of .327. As a squad, the New York Mets are knocking in 4.7 runs per contest, which ranks them 11th in the league.

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Their K/BB ratio is 2.48 and the pitching staff has a team WHIP of 1.33. Mets pitchers have surrendered 143 home runs and 683 total runs (18th in baseball). New York has conceded 1,291 hits (8.4 per 9 innings) and 612 earned runs. The Mets have a team ERA of 3.99 on the campaign (17th in baseball), and their staff has rung up 1,339 batters. Their pitching staff has walked 539 batters and their FIP is 3.89 as a unit for the year.

Mets relief pitchers have entered the game with runners on base 166 times in addition to having 180 appearances in high leverage situations. The bullpen have racked up 95 holds on the year (8th in the league). The Mets relief pitchers have earned a save rate of 58.5% and have come into the game in 161 save situations. They have accumulated 38 saves this year and have blown 27 out of their 65 chances to save the game. The relief pitchers have inherited 244 runners this season with 34.4% of those players earned a run for their team. The Mets have sent 514 relief pitchers to the hill this year.

The Mets have turned 68.8% of baseballs in play into outs in their 12,429 innings on the field, which ranks them 24th in the majors. The Minnesota Twins have a total of 4,143 putouts on the campaign, as well as 1,416 assists and 76 errors. Their fielding percentage is holding at .987 which is 13th in professional baseball, and have 117 double plays.

Tong has taken the ball for 16 innings and has totaled 21 K's in his career. His ERA is 6.11 (11 ER's allowed) and his WHIP is 1.481. He has given up 17 base hits (9.4 hits per nine innings) and has 7 free passes. Tong (2-2 career win-loss mark) holds a FIP of 6.02 and he has gone up against 73 batters in the major leagues.

The Chicago Cubs have accumulated a team on-base percentage of .320 as well as a team batting average of .249 on the season. They have been rung up on 1,222 occasions (26th in the league) and have recorded 1,316 base hits. Chicago has recorded 209 home runs on the campaign as well as 731 runs batted in. The Cubs have a team slugging percentage of .426 and they average 4.81 runs per outing (8th in the league). They have tallied 257 doubles, while getting a free base 536 times and earning 750 runs.

The Chicago pitching staff have surrendered 625 runs for the year while holding a team ERA of 3.82 (586 earned runs yielded). They have conceded 193 home runs and they relinquish 4.07 runs per 9 innings (6th in the league). The Cubs hold a team WHIP of 1.184 with a FIP of 4.18 as a team for the season. They currently have a K/BB ratio of 7.90 (1,207 strikeouts against 394 walks). They are currently ranked 10th in MLB as a pitching staff in total hits conceded with 1,241.

With 170 save situations, the Cubs have recorded 106 holds in addition to 19 blown saves. Chicago has called on relievers to step onto the mound in 61 save opportunities and they have walked away with 42 saves. Their bullpen pitchers have stepped onto the hill 153 times in high leverage situations in addition to 96 occasions with runners on. Chicago bullpen pitchers have an inherited score rate of 32.6% of 135 inherited base runners. They rank 4th in the league holding a save rate of 68.9%, and they have dispatched 503 relievers to the mound for the year.

In 12,429 innings played, the Cubs have a efficiency on defense of 71.8% (3rd in MLB). The Chicago Cubs have gotten 116 double plays and own a fielding percentage of .989 (5th in MLB). The Cubs have accrued 1,300 assists, 59 errors and have a tally of 4,143 putouts on the campaign.

In his career, Boyd has allowed 1,051 base hits and he has 1,042 strikeouts in 1,082 innings. He has conceded a total of 551 ER's while holding a WHIP of 1.281 and a FIP of 4.5. His strikeout to walk ratio is 3.11 and he has faced 4,594 hitters in his career. Boyd (59-77 career record) has a 4.58 earned run average and has allowed 8.7 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take New York (+126)

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