New York Mets vs Cincinnati Reds Prediction, 9/7/2025 MLB Picks, Best Bets & Odds
Game: New York Mets vs Cincinnati Reds
Date: Sunday, September 7, 2025
Location: Great American Ball Park in Cincinnati, OH
TV: FanDuel Sports Network Ohio
Odds/Point Spread: New York (-128) Cincinnati (+106)
The Cincinnati Reds (70-70) will try to defeat the New York Mets (75-65) at Great American Ball Park on Sunday. The odds on this game have the Mets at -128 while the Reds open at +106. The over/under is set at 8. The expected starting pitchers are Sean Manaea and Hunter Greene.


As a unit, the New York Mets are compiling 4.8 runs per game, which is 9th in baseball. They have accumulated 674 runs and hold an on-base percentage of .330. The Mets have tallied 231 doubles as a team and have knocked 193 baseballs out of the park. They have accrued 658 runs batted in in addition to 1,185 hits on the season, while their team batting average is sitting at .251. New York has a slugging rate of .431 and have been called out on strikes 1,114 times, while taking a walk on 497 occasions.
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Their K/BB ratio is 2.44 and the pitching staff has earned a collective WHIP of 1.32. Mets pitchers have given up 125 home runs in addition to 605 runs in total (15th in the league). New York has surrendered 1,149 hits (8.3 per 9 innings) and also 539 earned runs. The Mets have an ERA of 3.91 on the season (13th in MLB), and their staff has rung up 1,203 hitters. Their pitching staff has walked 493 opposing batters and their FIP comes in at 3.86 as a team so far this year.
Mets relief pitchers have stepped onto the hill with opponents on base 151 times in addition to having 166 appearances in high leverage situations. The relievers have recorded 86 holds so far this season (8th in MLB). The Mets relievers have compiled a save rate of 60.7% and have come into the game in 147 save situations. They have earned 37 saves on the campaign and have blown 24 of 61 save opportunities. The relief pitchers have inherited 226 base runners for the year and 34.1% of them ended up crossing the plate. The Mets have dispatched 458 relief pitchers to the hill so far this year.
The Minnesota Twins have a total of 3,720 putouts this season, in addition to 1,259 assists and 67 errors. Their fielding percentage is holding steady at .987 which puts them in 12th in pro baseball, and have 105 double plays. The Mets have turned 69.0% of balls hit into play into outs in their 11,160 innings, which has them sitting at 24th in baseball.
Manaea has taken the hill for 1,229 innings and has tallied 1,168 strikeouts in his career. His ERA is 4.06 (555 earned runs allowed) and he has a WHIP of 1.203. He has allowed 1,135 hits (8.3 hits per nine innings) with 344 free passes. Manaea (78-64 mark in his career) has earned a FIP of 4.00 and he has gone up against 5,131 batters in the majors.
The Cincinnati Reds have accumulated a team on-base percentage of .318 and a team batting average of .248 so far this season. They have been rung up on 1,216 occasions (9th in the league) and have earned a total of 1,173 hits. Cincinnati has knocked in 138 home runs for the year as well as 598 runs batted in. The Reds have a team slugging percentage of .393 and they average 4.53 runs per contest (13th in MLB). They have notched 229 doubles, while getting a free base 456 times and scoring 634 runs.
The Reds have a team WHIP of 1.250 with a FIP of 4.16 as a pitching staff this year. Their K/BB ratio comes in at 8.60 (1,186 strikeouts vs 438 free passes). They rank 8th in the league as a pitching staff in total hits relinquished with 1,111. They have allowed 166 homers and they allow 4.41 runs per 9 innings (16th in baseball). The Cincinnati pitching staff have conceded 607 runs so far this season while having an ERA of 3.95 (544 earned runs surrendered).
Sitting with 142 save situations, the Reds have accumulated 88 holds and also 20 blown saves. Cincinnati has called on relievers to enter the contest in 52 save opportunities and they have tallied 32 saves. Their relief pitchers have stepped onto the mound 142 times in high leverage situations and also on 127 occasions with runners on. Cincinnati bullpen pitchers have an inherited score percentage of 32.8% out of their 189 inherited runners. They sit at 20th in baseball with a save rate of 61.5%, and they have dispatched 481 relievers onto the field so far this season.
The Cincinnati Reds have gotten 90 double plays and have earned a fielding percentage of .984 (26th in professional baseball). The Reds have accrued 1,059 assists, 80 errors and have amassed 3,719 putouts for the season. In 11,157 innings played, the Reds have accumulated a defensive efficiency of 70.7% (8th in professional baseball).
Greene (23-29 career record) has a 3.69 earned run average and has surrendered 7.2 hits per nine innings. He has a strikeout to walk ratio of 3.45 and he has gone up against 1,969 opposing batters in his pro baseball career. He has conceded a total of 193 earned runs while earning a WHIP of 1.157 and having a FIP of 3.6. So far in his pro baseball career, Greene has given up 375 hits and he has 586 punch outs in 471 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take New York (-128)
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Additional Resources:
Cincinnati Reds - Twitter
New York Mets - Twitter