New York Yankees vs Minnesota Twins Prediction, 9/17/2025 MLB Picks, Best Bets & Odds

Game: New York Yankees vs Minnesota Twins

Date: Wednesday, September 17, 2025

Location: Target Field in Minneapolis, MN

TV: Twins.TV

Odds/Point Spread: New York (-275) Minnesota (+220)

The Minnesota Twins (66-84) host the New York Yankees (83-67) at Target Field on Wednesday. The odds on this game have New York at -275 while Minnesota opens at +220. The over/under has been set at 9. The pitchers taking the mound are Luis Gil and Taj Bradley.

As a team, the New York Yankees are earning 5.2 runs per game, which ranks them 1st in MLB. They have notched a total of 774 runs and have an OBP of .329. The Yankees have recorded 236 two-baggers as a team and have knocked 254 balls out of the park. They have accrued 747 runs batted in and 1,259 hits for the season, and their team batting average is .248. New York has a slugging rate of .452 and have been rung up 1,347 times, while drawing a walk on 583 occasions.

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They have a strikeout to walk ratio of 2.54 and their pitching staff has earned a collective WHIP of 1.27. Yankees pitchers have yielded 163 home runs and 652 runs in total (16th in MLB). New York has yielded 1,169 base hits (7.9 per 9 innings) and 595 earned runs. The Yankees hold a team earned run average of 4.02 so far this season (17th in baseball), and they have struck out 1,325 hitters. They have walked 521 opposing players and their FIP is 4.04 as a unit on the season.

Yankees relief pitchers have gone to the mound with runners on base 157 times and also have had 152 appearances in high leverage situations. The bullpen have a total of 92 holds this year (8th in the league). The Yankees bullpen have recorded a save percentage of 65.6% and have come into the game in 154 save situations. They have accumulated 40 saves on the season and have blown 21 of 61 save opportunities. The bullpen pitchers have inherited 240 runners on the campaign with 28.3% of them ended up scoring. The Yankees have dispatched 493 relief pitchers to the hill this season.

The Yankees have turned 70.4% of balls hit into play into outs out of 11,985 innings on the field, ranking them 11th in MLB. The New York Mets have accounted for 3,995 putouts thus far, as well as 1,301 assists and 87 errors. Their fielding rate is at .984 which has them ranked 25th in MLB, and have earned 102 double plays.

Gil (20-9 win-loss mark in his career) has a FIP of 3.37 while he has faced 962 batters during his time in the majors. He has conceded 160 base knocks (6.4 hits per nine innings) with 125 walks. His ERA is 3.42 (86 ER's allowed) and he has a WHIP of 1.261. Gil has taken the mound for 226 innings and has racked up 248 punch outs so far in his MLB career.

The Twins hold a slugging percentage of .400 and they are scoring 4.26 runs per outing (24th in baseball). They have tallied 231 two-baggers, while taking a walk 466 times and putting up 639 runs. Minnesota has compiled 179 home runs this season as well as 607 RBIs. They have been rung up on 1,244 occasions (16th in the league) and have tallied 1,208 hits. The Minnesota Twins have earned an OBP of .313 and a batting average of .240 for the year.

The Twins have a team WHIP of 1.328 in addition to having a FIP of 4.13 as a pitching staff on the season. They have earned a K/BB ratio of 8.60 (1,266 strikeouts vs 431 bases on balls). They come in at 25th in MLB as a pitching staff in total hits relinquished with 1,322. They have given up 180 homers and they relinquish 4.92 runs per 9 innings (24th in the league). The Minnesota pitching staff have allowed 721 runs on the campaign while holding an ERA of 4.58 (672 earned runs conceded).

Minnesota bullpen pitchers have an inherited score rate of 35.8% of 162 inherited runners. Their relievers have stepped onto the mound 165 times in high leverage situations and on 112 occasions with runners on. With 143 save situations, the Twins have accrued 90 holds and 24 blown saves. They rank 28th in baseball with a save percentage of 52.9%, and they have dispatched 506 relief pitchers to the mound so far this season. Minnesota has had bullpen pitchers step onto the hill in 51 save chances and they have come away with 27 saves.

The Minnesota Twins have turned 90 double plays and hold a fielding percentage of .985 (18th in pro baseball). The Twins have accrued 1,127 assists, 77 errors and have a total of 3,960 putouts for the season. In 11,880 innings on the field, the Twins have a defensive efficiency of 68.2% (29th in professional baseball).

So far in his pro baseball career, Bradley has allowed 349 base hits while totaling 397 strikeouts in 374 innings pitched. He has given up a total of 200 earned runs while holding a WHIP of 1.298 and a FIP of 4.7. He has a strikeout to walk ratio of 2.90 and he has gone up against 1,599 hitters in his pro baseball career. Bradley (19-26 career record) has earned a 4.81 ERA and has conceded 8.4 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Minnesota (+220)

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