New York Yankees vs St. Louis Cardinals Prediction, 8/15/2025 MLB Picks, Best Bets & Odds

Game: New York Yankees vs St. Louis Cardinals

Date: Friday, August 15, 2025

Location: Busch Stadium in St. Louis, MO

TV: FanDuel Sports Network Midwest

Odds/Point Spread: New York (-122) St. Louis (+102)

The St. Louis Cardinals (61-61) are hosting the New York Yankees (64-57) at Busch Stadium on Friday. The moneyline on this contest has the Yankees at -122 and the Cardinals are priced at +102. The over/under has been set at 8.5. The pitchers taking the mound are Luis Gil and Andre Pallante.

The Yankees have hit 196 doubles as a team and have smacked 191 baseballs out of the park. New York has a slugging % of .446 and have struck out 1,051 times, while drawing a walk on 460 occasions. As a team, the New York Yankees are notching 5.1 runs per game, which has them sitting at 4th in the league. They have compiled 587 runs batted in and 1,019 base knocks so far this season, while their batting average is sitting at .249. They have earned 612 runs while having a team on-base percentage of .328.

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The Yankees are sitting with a team ERA of 4.01 on the campaign (16th in the league), and their staff has struck out 1,076 hitters. Yankees pitchers have surrendered 136 home runs and 522 runs in total (17th in baseball). Their pitching staff has walked 420 opposing hitters and their FIP comes in at 4.04 as a team for the season. New York has conceded 923 base knocks (7.8 per 9 innings) as well as 478 earned runs. They have a strikeout to walk ratio of 2.56 and the pitching staff has a collective WHIP of 1.25.

Yankees pitchers have entered the game with runners on 131 times in addition to having 121 appearances in high leverage situations. The bullpen have earned 71 holds on the season (12th in baseball). The Yankees relievers have a save percentage of 64.6% and stepped onto the hill in 120 save situations. They have tallied 31 saves this year and have blown 17 of 48 save opportunities. The relievers have inherited 194 runners this year and 26.8% of those players ended up scoring. The Yankees have sent 403 relief pitchers to the hill for the year.

The Yankees have transformed 71.0% of balls in play into outs out of 9,645 innings on the diamond, which has them sitting 7th in pro baseball. The New York Mets have notched a total of 3,215 putouts on the campaign, in addition to 1,026 assists and 66 errors. Their fielding percentage is holding steady at .985 which ranks 22nd in the majors, and have accumulated 76 double plays.

Gil has thrown 193 innings and has earned 224 strikeouts during his MLB career. His earned run average is 3.73 (80 ER's allowed) and he has a career WHIP of 1.258. He has conceded 140 hits (6.5 hits per nine innings) and has 103 free passes. Gil (16-9 career mark) has a FIP of 3.67 while going up against 826 hitters during his time in the majors.

The Cardinals have a team SLG% of .386 and they tally 4.31 runs per contest (18th in MLB). They have put up 208 two-baggers, while walking 371 times and scoring 526 runs. St. Louis has a total of 115 home runs on the campaign as well as 502 RBIs. They have been called out on strikes on 945 occasions (24th in MLB) and have earned 1,022 hits. The St. Louis Cardinals have recorded an on-base percentage of .318 in addition to a batting average of .249 this season.

The St. Louis pitching staff have yielded 547 runs for the year while holding a team ERA of 4.19 (501 earned runs relinquished). They have given up 119 home runs and they give up 4.57 runs per 9 innings (23rd in baseball). The Cardinals hold a team WHIP of 1.280 with a FIP of 3.88 as a unit for the year. Their strikeout to walk ratio is 7.30 (880 strikeouts vs 314 bases on balls). They are sitting at 25th in baseball as a pitching staff in total hits surrendered with 1,065.

Sitting with 116 save situations, the Cardinals have accrued 67 holds in addition to 16 blown saves. St. Louis has called on bullpen pitchers to enter the game in 46 save opportunities and they have recorded 30 saves. Their bullpen pitchers have come in 115 times in high leverage situations in addition to 115 occasions with runners on. St. Louis relievers hold an inherited score percentage of 32.5% out of 157 inherited runners. They sit at 10th in MLB with a save percentage of 65.2%, and they have sent 360 relievers onto the diamond so far this season.

The St. Louis Cardinals have turned 91 double plays and own a fielding percentage of .987 (8th in pro baseball). The Cardinals have recorded 1,174 assists, 56 errors and are sitting with 3,233 putouts this year. In 9,699 innings on the diamond, the Cardinals hold a defensive efficiency of 69.4% (20th in MLB).

During his career, Pallante has conceded 427 base hits while he has totaled 290 strikeouts in 420 frames. He has allowed 193 ER's while holding a WHIP of 1.394 and a FIP of 4.1. He has a K/BB ratio of 1.82 and he has faced 1,800 hitters during his career. Pallante (24-23 career record) has earned a 4.13 earned run average and has conceded 9.1 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take St. Louis (+102) and under 8.5 runs

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