New York Yankees vs St. Louis Cardinals Prediction, 8/16/2025 MLB Picks, Best Bets & Odds
Game: New York Yankees vs St. Louis Cardinals
Date: Saturday, August 16, 2025
Location: Busch Stadium in St. Louis, MO
TV: FanDuel Sports Network Midwest
Odds/Point Spread: New York (-182) St. Louis (+150)
Busch Stadium is where the St. Louis Cardinals (61-61) will take on the New York Yankees (64-57) on Saturday. The moneyline on this game has New York at -182 and St. Louis is sitting at +150. The total is 8. The pitchers taking the mound will be Max Fried and Sonny Gray.


The Yankees have compiled 196 two-baggers as a unit and have hit 191 balls out of the stadium. New York has a slugging rate of .446 and have been rung up 1,051 times, while drawing a walk on 460 occasions. As a team, the New York Yankees are recording 5.1 runs/g, which puts them at 4th in MLB. They have earned 587 RBI's as well as 1,019 hits on the year, while their team batting average comes in at .249. They have earned 612 runs and hold an on-base percentage of .328.
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The Yankees have a team ERA of 4.01 for the year (16th in baseball), and their staff has rung up 1,076 hitters. Yankees pitchers have conceded 136 home runs in addition to 522 runs in total (17th in baseball). Their pitching staff has walked 420 opposing batters and their FIP comes in at 4.04 as a unit this season. New York has yielded 923 base hits (7.8 per 9 innings) as well as 478 earned runs. They have a strikeout to walk ratio of 2.56 and their pitching staff holds a WHIP of 1.25.
Yankees pitchers have entered the contest with runners on base 131 times and also have had 121 appearances in high leverage situations. The bullpen have accumulated 71 holds this season (12th in MLB). The Yankees relievers have earned a save percentage of 64.6% and stepped onto the hill in 120 save situations. They have recorded 31 saves so far this season and have blown 17 out of their 48 save chances. The bullpen pitchers have inherited 194 runners this year with 26.8% of them crossed home plate. The Yankees have sent 403 relievers to the mound on the campaign.
The Yankees have converted 71.0% of balls in play into outs out of their 9,645 innings on the field, which ranks them 7th in professional baseball. The New York Mets have earned a total of 3,215 putouts for the season, as well as 1,026 assists and 66 errors. Their fielding percentage is holding at .985 which puts them in 22nd in pro baseball, and have earned 76 double plays.
Fried has taken the mound for 1,028 innings and has totaled 998 punch outs in his MLB career. His earned run average is 3.06 (349 earned runs allowed) and his career WHIP is 1.155. He has surrendered 905 hits (7.9 hits per nine innings) and has had 282 free passes. Fried (85-41 career win-loss record) has earned a FIP of 3.01 and he has gone up against 4,207 opposing batters in the major leagues.
The St. Louis Cardinals have recorded an OBP of .318 and a batting average of .249 on the year. They have been rung up on 945 instances (24th in the league) and have earned 1,022 hits. St. Louis is sitting with 115 long balls on the season as well as 502 runs batted in. The Cardinals hold a slugging percentage of .386 and they average 4.31 runs per game (18th in MLB). They have put up 208 two-baggers, while getting a free base 371 times and scoring 526 runs.
The St. Louis pitching staff have relinquished 547 runs on the year while having an ERA of 4.19 (501 earned runs conceded). They have surrendered 119 HR's and they surrender 4.57 runs per 9 innings (23rd in the league). The Cardinals hold a team WHIP of 1.280 and have a FIP of 3.88 as a pitching staff so far this year. They have earned a K/BB ratio of 7.30 (880 strikeouts vs 314 free passes). They are sitting at 25th in the league as a pitching staff in total hits relinquished with 1,065.
St. Louis has called on relievers to step onto the mound in 46 save opportunities and they have tallied 30 saves. They rank 10th in the league holding a save rate of 65.2%, and they have sent 360 bullpen pitchers to the mound on the campaign. Their bullpen pitchers have stepped onto the hill 115 times in high leverage situations and on 115 occasions with runners on. St. Louis bullpen pitchers hold an inherited score rate of 32.5% out of 157 inherited base runners. With 116 save situations, the Cardinals have amassed 67 holds and 16 blown saves.
The St. Louis Cardinals have gotten 91 double plays and have earned a fielding percentage of .987 (8th in baseball). The Cardinals have 1,174 assists, 56 errors and have accumulated 3,233 putouts so far this year. In 9,699 innings on the diamond, the Cardinals have accumulated a efficiency on defense of 69.4% (20th in MLB).
Gray (122-99 career record) has a 3.55 earned run average while surrendering 7.8 hits per 9 innings. His K/BB ratio is 3.09 and he has faced 7,751 opposing batters so far in his pro baseball career. He has given up a total of 738 ER's while earning a WHIP of 1.191 and having a FIP of 3.5. During his career, Gray has allowed 1,624 base knocks while he has accumulated 1,872 strikeouts in 1,872 frames.
Who will win tonight's MLB game against the spread or moneyline?
Parlay's Pundit's Pick: Take St. Louis (+150) and under 8 runs
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Additional Resources:
St. Louis Cardinals - Twitter
New York Yankees - Twitter