Philadelphia Phillies vs Arizona Diamondbacks Prediction, 9/20/2025 MLB Picks, Best Bets & Odds

Game: Philadelphia Phillies vs Arizona Diamondbacks

Date: Saturday, September 20, 2025

Location: Chase Field in Phoenix, AZ

TV: DBACKS.TV

Odds/Point Spread: Philadelphia (-160) Arizona (+132)

The Arizona Diamondbacks (77-76) will take on the Philadelphia Phillies (91-62) at Chase Field on Saturday. The moneyline on this game has the Phillies at -160 and the Diamondbacks are priced at +132. The over/under is set at 9. The expected starting pitchers will be Taijuan Walker and Zac Gallen.

As a squad, the Philadelphia Phillies are earning 4.9 runs per outing, which has them at 8th in baseball. They have a total of 743 runs scored while holding a team on-base percentage of .330. The Phillies have compiled 255 two-baggers as a team and have knocked 197 balls out of the stadium. They have 718 RBI's in addition to 1,350 hits for the year, while their team batting average sits at .259. Philadelphia has a slugging rate of .431 and have been called out on strikes 1,245 times, while taking a walk on 504 occasions.

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Their strikeout to walk ratio is 3.35 and their pitching staff holds a collective WHIP of 1.24. Phillies pitchers have surrendered 167 long balls and 619 total runs (7th in MLB). Philadelphia has given up 1,269 hits (8.4 per 9 innings) as well as 582 earned runs. The Phillies have compiled a team ERA of 3.86 on the season (10th in the league), and they have rung up 1,389 batters. Their pitching staff has walked 415 opposing batters and their FIP comes in at 3.73 as a team this year.

Phillies relief pitchers have come into the game with runners on base 98 times and also have had 168 appearances in high leverage situations. The bullpen have notched 78 holds so far this season (22nd in the league). The Phillies bullpen have accumulated a save percentage of 63.4% and have entered the game in 152 save situations. They have recorded 45 saves this year and have not converted 26 of 71 save opportunities. The relievers have inherited 143 base runners on the season and 32.9% of them earned a run for their team. The Phillies have dispatched 476 relievers to the mound this season.

The Philadelphia Phillies have earned a total of 4,075 putouts thus far, as well as 1,305 assists and 56 errors. Their fielding rate is at .990 which ranks 3rd in pro baseball, and have 98 double plays. The Phillies have converted 69.1% of balls hit into play into outs in their 12,225 innings on the diamond, which has them ranked 21st in MLB.

Walker has pitched in 1,270 innings and has 1,081 K's in his pro baseball career. His earned run average is 4.19 (592 earned runs allowed) and his WHIP is 1.286. He has given up 1,204 base hits (8.5 hits per nine innings) and has 429 walks. Walker (77-71 win-loss mark in his career) has a FIP of 4.13 and he has faced 5,391 hitters in the major leagues.

The Arizona Diamondbacks have tallied an on-base percentage of .324 in addition to a batting average of .251 so far this year. They have struck out on 1,235 occasions (23rd in the league) and have accounted for 1,297 base hits. Arizona has 205 home runs on the season as well as 737 runs batted in. The Diamondbacks have a SLG% of .434 and they average 4.95 runs per contest (5th in baseball). They have notched 260 doubles, while taking a walk 513 times and scoring 758 runs.

The Arizona pitching staff have allowed 731 runs this season while having an ERA of 4.44 (673 earned runs relinquished). They have surrendered 181 dingers and they allow 4.82 runs per 9 innings (23rd in the league). The Diamondbacks hold a team WHIP of 1.309 with a FIP of 4.26 as a staff so far this season. They have earned a K/BB ratio of 8.00 (1,209 strikeouts vs 470 walks). They are sitting at 24th in MLB as a staff in total hits given up with 1,315.

Arizona has called on bullpen pitchers to take the mound in 70 save chances and they have converted 41 saves. They rank 22nd in the league holding a save rate of 58.6%, and they have sent 470 relievers to the hill for the year. Their relievers have come in 158 times in high leverage situations and also on 140 occasions with runners on. Arizona relievers hold an inherited score percentage of 34.1% out of 185 inherited runners. With 161 save situations, the Diamondbacks have amassed 86 holds in addition to 29 blown saves.

The Arizona Diamondbacks have turned 123 double plays and own a fielding percentage of .986 (15th in baseball). The Diamondbacks have racked up 1,376 assists, 77 errors and have amassed 4,092 putouts this season. In their 12,276 innings on the field, the Diamondbacks are sitting with a defensive efficiency of 69.7% (20th in baseball).

During his career, Gallen has surrendered 832 base knocks while he has tallied 1,048 K's in 995 innings. Gallen (65-51 win-loss record in his career) has earned a 3.55 earned run average and has surrendered 7.5 hits per nine innings. He has allowed a total of 393 earned runs while holding a WHIP of 1.156 and being the owner of a FIP of 3.5. He has a K/BB ratio of 3.29 and he has faced 4,090 opposing hitters in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Philadelphia (-160)

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