Philadelphia Phillies vs Chicago White Sox Prediction, 7/29/2025 MLB Picks, Best Bets & Odds

Game: Philadelphia Phillies vs Chicago White Sox

Date: Tuesday, July 29, 2025

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Philadelphia (-275) Chicago (+220)

The Philadelphia Phillies (60-45) are hitting the road to Rate Field on Tuesday where they will take on the Chicago White Sox (38-68). The line on this contest has the Phillies at -275 and the White Sox are priced at +220. The over/under comes in at 8.5. The pitchers taking the mound are Jesus Luzardo and Jonathan Cannon.

Philadelphia is slugging .413 and have been called out on strikes 826 times, while taking a walk on 361 occasions. They have accrued 467 runs batted in in addition to 907 hits on the year, while their batting average is .256. The Phillies have compiled 168 doubles as a team and have hit 120 baseballs out of the stadium. They have accounted for 490 runs while holding a team on-base percentage of .329. As a team, the Philadelphia Phillies are scoring 4.7 runs per game, which has them sitting at 8th in baseball.

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Their strikeout to walk ratio is 3.22 and their pitching staff has a collective WHIP of 1.26. Phillies pitchers have surrendered 111 long balls and 415 runs in total (8th in the league). Philadelphia has given up 863 base hits (8.4 per 9 innings) and 384 earned runs. The Phillies are sitting with a team ERA of 3.72 over the course of the season (8th in MLB), and their staff has rung up 971 batters. They have walked 302 opposing batters and their FIP sits at 3.63 as a team on the year.

Phillies bullpen pitchers have come into the game with runners on 69 times as well as having 110 appearances in high leverage situations. The relief pitchers have 48 holds for the year (25th in the league). The Phillies relief pitchers have recorded a save percentage of 61.4% and have entered the game in 93 save situations. They have earned 27 saves on the campaign and have blown 17 of their 44 save opportunities. The relief pitchers have inherited 99 base runners this year with 32.3% of them ended up scoring. The Phillies have dispatched 324 relief pitchers to the mound for the season.

The Phillies have turned 68.9% of balls in play into outs out of their 8,355 innings on the diamond, which has them sitting at 23rd in MLB. The Philadelphia Phillies have accumulated 2,785 putouts at this point in the season, as well as 894 assists and 37 errors. Their fielding rate is at .990 which ranks 3rd in the majors, and have earned 71 double plays.

Luzardo has thrown 626 frames and has totaled 695 K's in his pro baseball career. His earned run average is 4.34 (302 earned runs allowed) and he has a WHIP of 1.284. He has surrendered 581 hits (8.4 hits per 9 innings) with 223 walks. Luzardo (34-39 win-loss mark in his career) sits with a FIP of 4.28 while going up against 2,637 batters during his time in the majors.

Chicago has 90 long balls this year and 378 runs batted in. They have put up 169 doubles, while taking a walk 342 times as well as putting up 394 runs. The Chicago White Sox are sitting with an on-base percentage of .299 as well as a team batting average of .226 on the season. The White Sox hold a team slugging % of .359 and they average 3.75 runs per contest (27th in the league). They have struck out on 892 occasions (12th in the league) and have recorded 780 hits.

The White Sox hold a team WHIP of 1.379 and are the owners of a FIP of 4.46 as a pitching staff for the season. They have a ranking of 19th in the league as a staff in total hits given up with 876. The Chicago pitching staff have given up 464 runs for the season while having a team ERA of 4.11 (417 earned runs surrendered). They have earned a K/BB ratio of 7.50 (766 strikeouts against 385 walks). They have given up 112 homers and they surrender 4.57 runs per 9 innings (22nd in the league).

Chicago relief pitchers hold an inherited score percentage of 29.1% out of their 141 inherited runners. Their relief pitchers have stepped onto the mound 92 times in high leverage situations in addition to 96 occasions with base runners. Sitting with 72 save situations, the White Sox have amassed 43 holds and also 16 blown saves. They rank 30th in baseball holding a save rate of 44.8%, and they have sent 331 relief pitchers to the mound so far this season. Chicago has called on relief pitchers to step onto the hill in 29 save opportunities and they have earned 13 saves.

The Chicago White Sox have turned 90 double plays and own a fielding percentage of .983 (25th in baseball). The White Sox have recorded 869 assists, 63 errors and are sitting with 2,744 putouts over the course of the season. In 8,232 innings on the diamond, the White Sox have a defensive efficiency of 69.7% (16th in professional baseball).

Cannon (9-17 mark in his career) is the owner of a 4.50 earned run average while conceding 9.3 hits per nine innings. He has a K/BB ratio of 2.33 and he has gone up against 912 opposing hitters in his pro baseball career. He has conceded 106 ER's while earning a WHIP of 1.362 and a FIP of 4.4. Thus far in his career, Cannon has surrendered 219 base knocks and he has 163 punch outs in 212 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+220)

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