Philadelphia Phillies vs Houston Astros Prediction, 6/26/2025 MLB Picks, Best Bets & Odds
Game: Philadelphia Phillies vs Houston Astros
Date: Thursday, June 26, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: Philadelphia (-150) Houston (+125)
The Houston Astros (46-33) are welcoming the Philadelphia Phillies (47-32) at Daikin Park on Thursday. The moneyline on this game has the Phillies at -150 and the Astros are priced at +125. The over/under is 8.5. The expected starting pitchers will be Cristopher Sanchez and Hunter Brown.


As a squad, the Philadelphia Phillies are putting up 4.7 runs per game, which ranks them 7th in MLB. They have a total of 369 runs and have an on-base percentage of .332. The Phillies have compiled 125 doubles as a squad and have knocked 83 baseballs out of the stadium. They have amassed 352 RBI's and 684 base knocks on the campaign, while their batting average is sitting at .258. Philadelphia has a slugging rate of .407 and have struck out 607 times, while being walked on 274 occasions.
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The Phillies hold a team earned run average of 3.89 over the course of the season (16th in baseball), and they have struck out 717 hitters. Phillies pitchers have given up 85 home runs and also 328 runs in total (15th in baseball). Their pitching staff has walked 229 opposing batters and their FIP sits at 3.68 as a unit so far this season. Philadelphia has surrendered 663 base hits (8.5 per 9 innings) in addition to 302 earned runs. They have accrued a K/BB ratio of 3.13 and their pitching staff holds a collective WHIP of 1.28.
The Phillies have dispatched 246 relief pitchers to the mound over the course of the season. The relievers have inherited 73 base runners on the campaign and 41.1% of those players crossed the plate. They have compiled 24 saves this year and have blown 16 of 40 save opportunities. The Phillies bullpen have a save rate of 60.0% and have entered the game in 78 save situations. The relief pitchers have a total of 37 holds over the course of the season (27th in the league). Phillies relief pitchers have entered the contest with runners on 52 times and also have had 87 appearances in high leverage situations.
The Philadelphia Phillies have a total of 2,097 putouts on the campaign, in addition to 682 assists and 30 errors. Their fielding rate is holding at .989 which has them ranked 4th in pro baseball, and they have turned 50 double plays. The Phillies have transformed 68.6% of baseballs in play into outs in their 6,291 innings, which has them sitting 22nd in baseball.
Sanchez has thrown 420 frames and has 389 K's during his MLB career. Sanchez (23-18 career record) holds a FIP of 3.48 while he has faced 1,749 opposing batters during his time in the majors. His ERA is 3.53 (165 ER's allowed) and he has a career WHIP of 1.218. He has surrendered 400 base knocks (8.6 hits per 9 innings) and has had 112 walks.
The Houston Astros have a team OBP of .323 and a team batting average of .257 this year. They have struck out on 606 occasions (25th in baseball) and have 674 base knocks. Houston has knocked in 84 home runs so far this year and 317 runs batted in. The Astros hold a slugging percentage of .402 and they are scoring 4.27 runs per outing (16th in baseball). They have hit 113 two-baggers, while taking a walk 229 times as well as earning 333 runs.
The Astros have a team WHIP of 1.158 and are the owners of a FIP of 3.59 as a team on the campaign. Their K/BB ratio is 10.00 (768 strikeouts vs 236 bases on balls). They are currently ranked 1st in baseball as a staff in total hits given up with 562. They have allowed 84 homers and they relinquish 3.75 runs per 9 innings (5th in MLB). The Houston pitching staff have given up 287 runs this year while holding a team ERA of 3.53 (270 earned runs yielded).
Houston has called on bullpen pitchers to enter the game in 30 save opportunities and they have earned 22 saves. They are ranked 5th in the league with a save percentage of 73.3%, and they have sent 241 bullpen pitchers onto the field this season. Their bullpen pitchers have stepped onto the hill 77 times in high leverage situations and on 58 occasions with base runners. Houston relievers hold an inherited score percentage of 28.2% out of their 85 inherited base runners. With 78 save situations, the Astros have accrued 48 holds in addition to 8 blown saves.
The Houston Astros have turned 48 double plays and have earned a fielding percentage of .987 (14th in professional baseball). The Astros have recorded 586 assists, 36 errors and have a total of 2,069 putouts over the course of the season. In 6,207 innings on the field, the Astros are sitting with a defensive efficiency of 71.0% (8th in pro baseball).
So far in his pro baseball career, Brown has given up 384 base hits while tallying 488 strikeouts in 437 innings pitched. He has conceded 175 ER's while earning a WHIP of 1.222 and a FIP of 3.6. His K/BB ratio is 3.25 and he has gone up against 1,802 hitters during his MLB career. Brown (32-25 record in his career) has a 3.60 ERA and has surrendered 7.9 hits per nine innings.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Philadelphia (-150)
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Additional Resources:
Houston Astros - Twitter
Philadelphia Phillies - Twitter