Philadelphia Phillies vs Miami Marlins Prediction, 9/6/2025 MLB Picks, Best Bets & Odds

Game: Philadelphia Phillies vs Miami Marlins

Date: Saturday, September 6, 2025

Location: loanDepot park in Miami, FL

TV: FanDuel Sports Network Florida

Odds/Point Spread: Philadelphia (-130) Miami (+110)

loanDepot park is the location where the Miami Marlins (65-75) will try to beat the Philadelphia Phillies (80-59) on Saturday. The line on this contest has the Phillies at -130 while the Marlins are coming in at +110. The over/under is 9. The pitchers taking the mound are Jesus Luzardo and Sandy Alcantara.

The Phillies have hit 228 doubles as a team and have knocked 172 baseballs out of the park. Philadelphia is slugging .424 and have been called out on strikes 1,120 times, while taking a walk on 455 occasions. As a team, the Philadelphia Phillies are notching 4.8 runs per game, which is 10th in baseball. They have 638 RBI's as well as 1,220 hits on the season, and their batting average sits at .258. They have accumulated 663 runs scored and hold an on-base percentage of .328.

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Their strikeout to walk ratio sits at 3.35 and the pitching staff has a collective WHIP of 1.24. Phillies pitchers have conceded 149 home runs in addition to 565 runs in total (5th in baseball). Philadelphia has surrendered 1,156 base hits (8.4 per 9 innings) as well as 528 earned runs. The Phillies have an earned run average of 3.85 over the course of the season (7th in baseball), and their staff has struck out 1,271 batters. They have walked 379 opposing batters and their FIP sits at 3.68 as a team so far this season.

The Phillies have sent 435 relief pitchers to the hill on the campaign. The bullpen pitchers have inherited 136 runners this season with 33.8% of them crossed the plate. They have earned 38 saves on the season and have blown 23 of their 61 save opportunities. The Phillies relievers have a save percentage of 62.3% and stepped onto the hill in 131 save situations. The bullpen have a total of 67 holds for the season (23rd in baseball). Phillies pitchers have come into the game with runners on base 93 times in addition to having 151 appearances in high leverage situations.

The Philadelphia Phillies have accounted for 3,700 putouts for the season, as well as 1,187 assists and 52 errors. Their fielding percentage is holding steady at .989 which ranks 3rd in pro baseball, and have accumulated 90 double plays. The Phillies have turned 68.8% of balls hit into play into outs out of 11,100 innings on the field, ranking them 25th in professional baseball.

Luzardo has taken the mound for 667 frames and has accumulated 741 K's so far in his MLB career. His ERA is 4.24 (314 ER's allowed) and he has a WHIP of 1.260. He has conceded 609 base knocks (8.2 hits per 9 innings) with 232 walks. Luzardo (38-40 career mark) sits with a FIP of 4.17 while facing 2,799 batters during his time in the major leagues.

Miami has compiled 132 home runs on the campaign to go along with 575 RBIs. They have recorded 232 two-baggers, while getting a free base 420 times and scoring 606 runs. The Miami Marlins have compiled an OBP of .314 and a team batting average of .250 on the year. The Marlins hold a slugging % of .392 and they score 4.33 runs per game (18th in the league). They have struck out on 1,104 occasions (25th in the league) and have a total of 1,194 hits.

The Marlins hold a team WHIP of 1.310 in addition to having a FIP of 4.30 as a unit on the year. Their K/BB ratio is 8.00 (1,103 strikeouts against 439 bases on balls). They are sitting at 22nd in the league as a pitching staff in total hits relinquished with 1,186. They have relinquished 164 dingers and they yield 5.07 runs per 9 innings (26th in MLB). The Miami pitching staff have relinquished 699 runs this year while having an ERA of 4.70 (648 earned runs conceded).

Miami relievers hold an inherited score percentage of 32.5% out of their 157 inherited base runners. Their relief pitchers have come in 147 times in high leverage situations and also on 108 occasions with runners on base. With 128 save situations, the Marlins have amassed 73 holds and 20 blown saves. They are ranked 12th in MLB holding a save percentage of 63.0%, and they have dispatched 434 relievers onto the field so far this season. Miami has had relief pitchers step onto the hill in 54 save opportunities and they have earned 34 saves.

In their 11,163 innings on the field, the Marlins hold a defensive efficiency of 69.9% (14th in MLB). The Miami Marlins have gotten 93 double plays and own a fielding percentage of .986 (17th in baseball). The Marlins have accrued 1,194 assists, 72 errors and have earned a total of 3,721 putouts on the season.

During his MLB career, Alcantara has surrendered 912 hits and he has 908 punch outs in 1,048 innings. He has conceded a total of 425 earned runs while holding a WHIP of 1.180 and having a FIP of 3.6. His strikeout to walk ratio is 2.79 and he has faced 4,319 batters in his pro baseball career. Alcantara (49-66 career record) is the owner of a 3.65 ERA and has given up 7.8 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Miami (+110)

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