Pittsburgh Pirates vs Milwaukee Brewers Prediction, 6/25/2025 MLB Picks, Best Bets & Odds

Game: Pittsburgh Pirates vs Milwaukee Brewers

Date: Wednesday, June 25, 2025

Location: American Family Field in Milwaukee, WI

TV: FanDuel Sports Network Wisconsin

Odds/Point Spread: Pittsburgh (+172) Milwaukee (-210)

The Pittsburgh Pirates (32-48) are headed to American Family Field on Wednesday where they will try to defeat the Milwaukee Brewers (43-36). The odds on this game have the Pirates at +172 while the Brewers are priced at -210. The total is set at 8.5. The expected starting pitchers will be Paul Skenes and Jacob Misiorowski.

Pittsburgh is slugging .339 and have been called out on strikes 697 times, while drawing a walk on 262 occasions. They have accounted for 252 runs batted in in addition to 607 hits this season, and their batting average is sitting at .229. The Pirates have earned 101 doubles as a team and have smacked 54 balls out of the stadium. They have a total of 262 runs scored while holding a team on-base percentage of .304. As a squad, the Pittsburgh Pirates are knocking in 3.3 runs per game, which is 30th in the league.

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The Pirates have a team ERA of 3.81 so far this season (11th in MLB), and they have struck out 593 hitters. Pirates pitchers have conceded 68 long balls in addition to 322 runs (12th in MLB). Their pitching staff has walked 242 opposing hitters and their FIP is 3.79 as a unit on the year. Pittsburgh has yielded 614 base hits (7.8 per 9 innings) and also 301 earned runs. Their strikeout to walk ratio is 2.45 and the pitching staff holds a WHIP of 1.21.

The Pirates bullpen have a save rate of 53.1% and have entered the game in 74 save situations. The bullpen pitchers have inherited 119 runners over the course of the season and 36.1% of them ended up crossing the plate. Pirates pitchers have stepped onto the hill with players on base 76 times in addition to having 85 appearances in high leverage situations. The Pirates have sent 253 relief pitchers to the mound on the season. The bullpen have a total of 40 holds so far this season (22nd in the league). They have earned 17 saves on the season and have blown 15 of 32 save opportunities.

The Pittsburgh Pirates have accumulated 2,131 putouts thus far, as well as 705 assists and 39 errors. Their fielding percentage is holding steady at .986 which ranks 16th in the majors, and have 68 double plays. The Pirates have converted 71.7% of balls hit into play into outs out of their 6,393 innings on the field, which has them sitting at 4th in pro baseball.

Skenes (15-9 career mark) has earned a FIP of 1.89 while he has faced 904 batters in the majors. He has allowed 157 base knocks (6.0 hits per nine innings) and has had 59 walks. His ERA is 1.91 (50 ER's allowed) and he has a WHIP of 0.919. Skenes has thrown 235 innings and is sitting with 276 strikeouts so far in his MLB career.

The Milwaukee Brewers have compiled an OBP of .321 as well as a batting average of .246 so far this season. They have been rung up on 647 instances (16th in baseball) and have 649 hits. Milwaukee has accounted for 72 long balls so far this season as well as 340 RBIs. The Brewers have a slugging percentage of .377 and they average 4.63 runs per contest (12th in MLB). They have put up 115 doubles, while getting a free base 271 times as well as scoring 366 runs.

The Brewers are sitting with a team WHIP of 1.308 with a FIP of 4.14 as a squad over the course of the season. They are sitting at 14th in baseball as a pitching staff in total hits allowed with 636. The Milwaukee pitching staff have relinquished 326 runs this season and come in with a team ERA of 3.87 (301 earned runs allowed). They have earned a K/BB ratio of 8.40 (657 strikeouts vs 280 free passes). They have surrendered 87 long balls and they allow 4.19 runs per 9 innings (13th in baseball).

Milwaukee has had bullpen pitchers enter the game in 31 save opportunities and they have earned 21 saves. They sit at 9th in the league holding a save rate of 67.7%, and they have dispatched 276 relief pitchers onto the diamond over the course of the season. Their relievers have come in 89 times in high leverage situations and also on 73 occasions with base runners. Milwaukee relievers have an inherited score percentage of 33.3% of 111 inherited runners. Sitting with 84 save situations, the Brewers have accrued 51 holds and 10 blown saves.

The Milwaukee Brewers have turned 57 double plays and hold a fielding percentage of .986 (18th in the majors). The Brewers have 626 assists, 39 errors and have accounted for 2,101 putouts during this campaign. In 6,303 innings on the field, the Brewers have earned a defensive efficiency of 70.3% (12th in pro baseball).

During his pro baseball career, Misiorowski has allowed 1 base knocks while he has totaled 11 K's in 11 innings pitched. Misiorowski (2-0 win-loss mark in his career) has a 1.64 earned run average while allowing 0.8 hits per 9 innings. He has given up a total of 2 ER's while holding a WHIP of 0.545 and having a FIP of 1.6. He has a strikeout to walk ratio of 2.20 and he has gone up against 38 hitters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Pittsburgh (+172)

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