Pittsburgh Pirates vs San Diego Padres Prediction, 6/1/2025 MLB Picks, Best Bets & Odds
Game: Pittsburgh Pirates vs San Diego Padres
Date: Sunday, June 1, 2025
Location: Petco Park in San Diego, CA
TV: Padres.TV
Odds/Point Spread: Pittsburgh (+126) San Diego (-152)
Petco Park is the location where the San Diego Padres (31-23) will compete against the Pittsburgh Pirates (21-36) on Sunday. The moneyline on this matchup has the Pirates at +126 and the Padres are at -152. The total is 8.5. The pitchers taking the mound are Andrew Heaney and Randy Vasquez.


As a unit, the Pittsburgh Pirates are earning 3.2 runs per game, which has them sitting at 29th in the league. They have earned 183 runs scored and have an OBP of .306. The Pirates have tallied 69 two-baggers as a squad and have knocked 40 balls out of the stadium. They have accrued 177 runs batted in and 428 hits on the campaign, and their team batting average is sitting at .226. Pittsburgh has a slugging % of .337 and have struck out 490 times, while being walked on 200 occasions.
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The Pirates are sitting with a team ERA of 3.99 so far this season (19th in baseball), and their staff has rung up 423 hitters. Pirates pitchers have given up 47 home runs and 243 total runs (19th in MLB). Their pitching staff has walked 181 batters and their FIP is 3.83 as a unit so far this season. Pittsburgh has given up 460 hits (8.2 per 9 innings) and also 225 earned runs. They have earned a K/BB ratio of 2.34 and their pitching staff holds a WHIP of 1.26.
Pirates pitchers have stepped onto the hill with opponents on base 57 times and also have had 64 appearances in high leverage situations. The relievers have notched 30 holds for the year (19th in MLB). The Pirates relievers have recorded a save percentage of 52.2% and have entered the game in 54 save situations. They have earned 12 saves for the season and have blown 11 of 23 save chances. The relievers have inherited 91 runners on the season with 36.3% of those runners earned a run for their team. The Pirates have sent 188 relievers to the hill this season.
The Pirates have transformed 70.3% of baseballs in play into outs in their 4,563 innings, ranking them 12th in baseball. The Pittsburgh Pirates have 1,521 putouts thus far, in addition to 510 assists and 33 errors. Their fielding rate is currently at .984 which has them sitting 23rd in pro baseball, and have accumulated 50 double plays.
Heaney (54-66 record in his career) has a FIP of 4.33 while he has gone up against 4,583 hitters in the major leagues. He has surrendered 1,034 base knocks (8.7 hits per nine innings) and has had 323 walks. His earned run average is 4.40 (525 earned runs allowed) and he has a WHIP of 1.263. Heaney has thrown 1,074 innings and has accounted for 1,114 punch outs during his MLB career.
The San Diego Padres have accumulated an on-base percentage of .319 in addition to a batting average of .253 for the year. They have been called out on strikes on 379 instances (30th in baseball) and have notched a total of 457 hits. San Diego has tallied 52 home runs this season to go along with 213 runs batted in. The Padres have a team slugging % of .391 and they average 4.31 runs per game (15th in MLB). They have recorded 79 two-baggers, while taking a walk 169 times as well as scoring 233 runs.
The San Diego pitching staff have relinquished 215 runs on the year and come in with a team ERA of 3.61 (192 earned runs conceded). They have allowed 57 homers and they yield 4.04 runs per 9 innings (11th in the league). The Padres have a team WHIP of 1.205 with a FIP of 3.87 as a staff this year. Their K/BB ratio sits at 8.80 (469 strikeouts against 173 walks). They rank 3rd in the league as a pitching staff in total hits given up with 404.
San Diego has called on bullpen pitchers to enter the contest in 26 save opportunities and they have recorded 19 saves. They are ranked 4th in baseball with a save percentage of 73.1%, and they have dispatched 188 relievers to the hill on the year. Their bullpen pitchers have stepped onto the mound 74 times in high leverage situations and on 58 occasions with base runners. San Diego relievers hold an inherited score rate of 41.8% out of 79 inherited runners. With 64 save situations, the Padres have recorded 37 holds and also 7 blown saves.
The San Diego Padres have gotten 42 double plays and hold a fielding percentage of .985 (21st in baseball). The Padres have racked up 410 assists, 29 errors and have accounted for 1,437 putouts this season. Out of their 4,311 innings on the field, the Padres have earned a defensive efficiency of 71.3% (7th in MLB).
Vasquez (9-13 mark in his career) is the owner of a 4.11 earned run average and has conceded 9.4 hits per nine innings. He has a strikeout to walk ratio of 1.72 and he has faced 836 batters in his career. He has conceded a total of 87 ER's while holding a WHIP of 1.435 and being the owner of a FIP of 4.1. In his MLB career, Vasquez has allowed 199 hits while he has tallied 127 K's in 190 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take San Diego (-152)
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Additional Resources:
San Diego Padres - Twitter
Pittsburgh Pirates - Twitter