San Diego Padres vs Chicago Cubs Prediction, 4/5/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Chicago Cubs

Date: Saturday, April 5, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: San Diego (-160) Chicago (+132)

Wrigley Field is the location where the Chicago Cubs (5-4) will attempt to defeat the San Diego Padres (7-0) on Saturday. The odds on this game have San Diego at -160 while Chicago is at +132. The over/under is set at 8.5. The expected starting pitchers are Nick Pivetta and Matthew Boyd.

San Diego has a slugging % of .440 and have been rung up 40 times, while taking a walk on 26 occasions. They have tallied 33 runs batted in and 65 hits on the campaign, and their team batting average is sitting at .298. The Padres have earned 13 doubles as a squad and have knocked 6 balls out of the park. They have 36 runs and hold an OBP of .369. As a team, the San Diego Padres are notching 5.1 runs per outing, which has them at 8th in MLB.

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The Padres are sitting with a team earned run average of 1.57 for the year (1st in baseball), and they have struck out 69 hitters. Padres pitchers have conceded 5 home runs and 11 runs (1st in the league). They have walked 21 opposing hitters and their FIP sits at 2.81 as a squad on the year. San Diego has conceded 36 base knocks (5.1 per 9 innings) as well as 11 earned runs. Their strikeout to walk ratio is 3.29 and their pitching staff holds a collective WHIP of 0.90.

The Padres relief pitchers have earned a save percentage of 100.0% and has entered the game in 10 save situations. The relievers have inherited 9 runners on the campaign and 0.0% of them earned a run for their team. Padres bullpen pitchers have gone to the mound with runners on base 6 times in addition to having 8 appearances in high leverage situations. The Padres have dispatched 26 relievers to the mound so far this year. The relief pitchers have a total of 6 holds for the year (8th in MLB). They have compiled 4 saves this season and have blown 0 of their 4 save chances.

The San Diego Padres are sitting with 189 putouts at this point in the season, in addition to 52 assists and 2 errors. Their fielding percentage sits at .992 which has them sitting 8th in MLB, and have a total of 6 double plays. The Padres have converted 77.7% of balls in play into outs in their 567 innings on the diamond, which has them sitting at 4th in the majors.

Pivetta has taken the mound for 1,036 innings and has racked up 1,143 punch outs so far in his career. Pivetta (57-71 career win-loss mark) holds a FIP of 4.65 and he has faced 4,407 opposing hitters in the major leagues. His ERA is 4.73 (544 ER's allowed) and he has a career WHIP of 1.309. He has allowed 979 base hits (8.5 hits per 9 innings) with 377 free passes.

The Chicago Cubs have earned an OBP of .344 as well as a team batting average of .255 for the year. They have struck out on 79 occasions (1st in MLB) and have tallied 84 base hits. Chicago has recorded 14 HRs so far this year to go along with 60 RBIs. The Cubs hold a slugging % of .450 and they average 6.67 runs per contest (3rd in the league). They have recorded 20 doubles, while taking a walk 43 times and putting up 60 runs.

The Cubs hold a team WHIP of 1.544 and are the owners of a FIP of 4.83 as a pitching staff on the year. They currently have a K/BB ratio of 7.10 (62 strikeouts against 39 walks). They are currently ranked 30th in baseball as a pitching staff in total hits surrendered with 83. They have allowed 12 long balls and they relinquish 5.24 runs per 9 innings (24th in MLB). The Chicago pitching staff have allowed 46 runs so far this year while having a team ERA of 5.13 (45 earned runs conceded).

With 11 save situations, the Cubs have tallied 7 holds and 1 blown save. Chicago has had relievers take the mound in 4 save opportunities and they have tallied 3 saves. Their relief pitchers have stepped onto the mound 2 times in high leverage situations and on 5 occasions with base runners. Chicago relievers have an inherited score rate of 57.1% out of 7 inherited runners. They are currently ranked 12th in the league with a save rate of 75.0%, and they have dispatched 28 relievers onto the diamond for the year.

Out of their 711 innings on the field, the Cubs have a defensive efficiency of 68.8% (24th in professional baseball). The Chicago Cubs have turned 10 double plays and have notched a fielding percentage of .988 (12th in the majors). The Cubs have racked up 82 assists, 4 errors and have earned a total of 237 putouts so far this season.

So far in his career, Boyd has allowed 903 base hits while tallying 896 punch outs in 913 innings pitched. Boyd (46-69 career win-loss mark) has a 4.82 earned run average and has allowed 8.9 hits per nine innings. He has conceded a total of 489 ER's while earning a WHIP of 1.314 and a FIP of 4.7. He has a K/BB ratio of 3.02 and he has gone up against 3,918 batters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Chicago (+132) and under 8.5 runs

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