San Diego Padres vs Cincinnati Reds Prediction, 6/28/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Cincinnati Reds

Date: Saturday, June 28, 2025

Location: Great American Ball Park in Cincinnati, OH

TV: FanDuel Sports Network Ohio

Odds/Point Spread: San Diego (-150) Cincinnati (+125)

Great American Ball Park is the site where the Cincinnati Reds (42-39) will play the San Diego Padres (44-36) on Saturday. The moneyline on this contest has San Diego at -150 and Cincinnati is coming in at +125. The betting total comes in at 8.5. The pitchers who are expected to start are Randy Vasquez and Andrew Abbott.

The Padres have tallied 118 doubles as a unit and have hit 69 baseballs out of the park. San Diego is slugging .379 and have struck out 561 times, while being walked on 252 occasions. As a unit, the San Diego Padres are scoring 4.2 runs per game, which has them at 21st in baseball. They have earned 312 RBI's in addition to 661 base knocks for the year, and their team batting average comes in at .248. They have accounted for 336 runs while holding a team on-base percentage of .316.

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They have earned a strikeout to walk ratio of 2.66 and the pitching staff holds a WHIP of 1.22. Padres pitchers have surrendered 79 long balls in addition to 313 runs (9th in MLB). San Diego has surrendered 600 base hits (7.6 per 9 innings) and 283 earned runs. The Padres are sitting with a team earned run average of 3.59 this season (9th in MLB), and the staff has struck out 697 hitters. Their pitching staff has walked 262 players from the other team and their FIP sits at 3.80 as a unit on the year.

The Padres have sent 281 relievers to the hill this year. The relief pitchers have inherited 127 base runners so far this season and 35.4% of those players crossed the plate. They have recorded 27 saves for the season and have blown 9 of their 36 chances to save the game. The Padres relievers have recorded a save percentage of 75.0% and stepped onto the hill in 89 save situations. The bullpen have a total of 52 holds on the season (9th in baseball). Padres relief pitchers have gone to the mound with players on base 90 times in addition to having 111 appearances in high leverage situations.

The San Diego Padres have earned 2,126 putouts so far this season, in addition to 607 assists and 39 errors. Their fielding percentage is at .986 which puts them in 18th in MLB, and have 56 double plays. The Padres have converted 71.2% of balls in play into outs out of 6,378 innings, which has them sitting at 6th in baseball.

Vasquez has taken the hill for 215 innings and has accumulated 140 strikeouts in his pro baseball career. Vasquez (9-13 win-loss mark in his career) sits with a FIP of 4.00 while facing 940 opposing batters in the major leagues. His earned run average is 4.06 (97 ER's allowed) and his WHIP is 1.403. He has conceded 218 hits (9.1 hits per nine innings) and has 84 walks.

The Cincinnati Reds have earned an on-base percentage of .319 and a team batting average of .247 this season. They have struck out on 704 occasions (9th in baseball) and have 670 base hits. Cincinnati has a total of 88 long balls so far this year and 356 runs batted in. The Reds hold a slugging % of .401 and they earn 4.59 runs per game (12th in MLB). They have hit 135 doubles, while taking a walk 274 times as well as scoring 372 runs.

The Reds have a team WHIP of 1.220 and are the owners of a FIP of 4.17 as a squad this season. They sit at 9th in baseball as a staff in total hits given up with 627. The Cincinnati pitching staff have surrendered 338 runs for the season and come in with a team ERA of 3.85 (307 earned runs yielded). Their strikeout to walk ratio comes in at 8.20 (657 strikeouts against 248 free passes). They have surrendered 96 dingers and they surrender 4.24 runs per 9 innings (16th in MLB).

Cincinnati has called on bullpen pitchers to enter the contest in 30 save chances and they have earned 21 saves. They sit at 6th in the league holding a save percentage of 70.0%, and they have sent 274 relievers to the mound so far this season. Their relief pitchers have taken the field 72 times in high leverage situations and on 62 occasions with runners on. Cincinnati relievers hold an inherited score percentage of 33.0% out of their 94 inherited base runners. Sitting with 84 save situations, the Reds have 52 holds in addition to 9 blown saves.

In their 6,459 innings on the field, the Reds have a efficiency on defense of 71.9% (3rd in pro baseball). The Cincinnati Reds have gotten 48 double plays and have a fielding percentage of .986 (15th in professional baseball). The Reds have 613 assists, 38 errors and have a total of 2,153 putouts this season.

Abbott (25-17 career mark) is the owner of a 3.32 earned run average and has allowed 7.8 hits per 9 innings. He has a K/BB ratio of 2.64 and he has faced 1,341 hitters during his career. He has conceded 119 ER's while earning a WHIP of 1.229 and having a FIP of 3.3. So far in his MLB career, Abbott has surrendered 280 base knocks while he has earned 306 strikeouts in 322 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take San Diego (-150)

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