San Diego Padres vs Colorado Rockies Prediction, 5/9/2025 MLB Picks, Best Bets & Odds
Game: San Diego Padres vs Colorado Rockies
Date: Friday, May 9, 2025
Location: Coors Field in Denver, CO
TV: Rockies.TV
Odds/Point Spread: San Diego (-275) Colorado (+220)
The San Diego Padres (23-13) are headed to Coors Field on Friday where they will meet the Colorado Rockies (6-29). The odds on this game have the Padres at -275 and the Rockies are opening at +220. The over/under is set at 9. The pitchers who are expected to start will be Randy Vasquez and Antonio Senzatela.


San Diego is slugging .382 and have struck out 250 times, while taking a walk on 115 occasions. They have accumulated 131 runs batted in in addition to 301 hits this season, and their batting average is .256. The Padres have hit 53 two-baggers as a squad and have knocked 30 baseballs out of the park. They have earned 143 runs and have an OBP of .324. As a unit, the San Diego Padres are earning 4.0 runs per contest, which has them sitting at 21st in baseball.
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They have a strikeout to walk ratio of 2.61 and the pitching staff has a collective WHIP of 1.14. Padres pitchers have given up 30 home runs and 114 total runs (1st in MLB). San Diego has conceded 244 base hits (6.9 per 9 innings) as well as 106 earned runs. The Padres are sitting with a team earned run average of 3.00 this year (3rd in baseball), and their staff has rung up 310 hitters. They have walked 119 opposing players and their FIP sits at 3.60 as a unit for the season.
Padres relief pitchers have entered the game with runners on 28 times and also have had 49 appearances in high leverage situations. The bullpen have recorded 28 holds on the year (6th in MLB). The Padres relief pitchers have compiled a save rate of 88.2% and stepped onto the hill in 46 save situations. They have recorded 15 saves so far this year and have missed out on 2 of 17 chances to save the game. The relief pitchers have inherited 41 runners on the year and 34.1% of those players earned a run for their team. The Padres have dispatched 125 relievers to the mound for the year.
The Padres have turned 72.9% of balls in play into outs out of 2,859 innings, which has them sitting 2nd in MLB. The San Diego Padres have a total of 953 putouts for the season, in addition to 259 assists and 18 errors. Their fielding percentage is currently at .985 which puts them in 15th in pro baseball, and they have turned 25 double plays.
Vasquez has taken the mound for 167 innings and is sitting with 108 punch outs so far in his MLB career. Vasquez (7-12 mark in his career) has a FIP of 4.19 while he has faced 745 opposing batters during his time in the major leagues. His earned run average is 4.25 (79 earned runs allowed) and his WHIP is 1.494. He has allowed 179 hits (9.6 hits per nine innings) and has 71 free passes.
The Colorado Rockies hold an on-base percentage of .282 as well as a team batting average of .213 so far this year. They have been rung up on 352 occasions (1st in the league) and have a total of 247 hits. Colorado has knocked in 29 home runs over the course of the season as well as 111 runs batted in. The Rockies hold a slugging percentage of .350 and they earn 3.20 runs per contest (29th in MLB). They have recorded 53 two-baggers, while taking a walk 101 times as well as scoring 112 runs.
The Rockies hold a team WHIP of 1.554 in addition to having a FIP of 4.64 as a unit so far this year. They sit at 29th in baseball as a pitching staff in total hits relinquished with 347. The Colorado pitching staff have relinquished 203 runs on the campaign and come in with a team ERA of 5.38 (181 earned runs given up). Their strikeout to walk ratio sits at 7.00 (234 strikeouts vs 124 walks). They have relinquished 41 home runs and they give up 6.03 runs per 9 innings (29th in MLB).
Colorado relievers hold an inherited score percentage of 32.2% of 87 inherited runners. Their bullpen pitchers have stepped onto the hill 37 times in high leverage situations and on 47 occasions with runners on base. With 22 save situations, the Rockies have amassed 11 holds in addition to 6 blown saves. They rank 28th in MLB with a save rate of 45.5%, and they have sent 117 relievers onto the diamond this season. Colorado has had bullpen pitchers step onto the mound in 11 save opportunities and they have come away with 5 saves.
In 2,727 innings on the diamond, the Rockies have accumulated a defensive efficiency of 65.9% (30th in MLB). The Colorado Rockies have gotten 30 double plays and have earned a fielding percentage of .980 (27th in baseball). The Rockies have 347 assists, 26 errors and have notched a total of 909 putouts for the year.
In his MLB career, Senzatela has given up 844 base hits while he has accumulated 475 punch outs in 726 innings. He has conceded a total of 398 earned runs while holding a WHIP of 1.471 and a FIP of 4.9. He has a K/BB ratio of 2.12 and he has faced 3,166 opposing hitters in his pro baseball career. Senzatela (40-49 record in his career) holds a 4.93 earned run average while surrendering 10.5 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take San Diego (-275)
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Additional Resources:
Colorado Rockies - Twitter
San Diego Padres - Twitter