San Diego Padres vs Detroit Tigers Prediction, 4/22/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Detroit Tigers

Date: Tuesday, April 22, 2025

Location: Comerica Park in Detroit, MI

TV: FanDuel Sports Network Detroit

Odds/Point Spread: San Diego (-182) Detroit (+150)

The Detroit Tigers (13-9) will compete against the San Diego Padres (16-6) at Comerica Park on Tuesday. The odds on this game have San Diego at -182 while Detroit is at +150. The over/under has been set at 8.5. The pitchers expected to start will be Nick Pivetta and Jack Flaherty.

San Diego owns a slugging percentage of .424 and have struck out 141 times, while taking a walk on 77 occasions. They have recorded 88 RBI's and 201 base knocks this year, and their average at the plate comes in at .276. The Padres have earned 39 doubles as a unit and have hit 22 baseballs out of the park. They have tallied 97 runs and hold an OBP of .346. As a unit, the San Diego Padres are earning 4.4 runs per contest, which is 14th in the league.

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The Padres have a team ERA of 2.74 so far this year (2nd in the league), and they have struck out 187 hitters. Padres pitchers have yielded 16 long balls in addition to 62 total runs (2nd in MLB). Their pitching staff has walked 69 opposing batters and their FIP sits at 3.31 as a squad over the course of the season. San Diego has surrendered 143 hits (6.6 per 9 innings) as well as 59 earned runs. They have earned a strikeout to walk ratio of 2.71 and the pitching staff sits with a WHIP of 1.09.

Padres pitchers have come into the game with runners on 16 times in addition to having 30 appearances in high leverage situations. The relief pitchers have a total of 18 holds this season (5th in the league). The Padres bullpen have a save percentage of 90.9% and have entered the game in 29 save situations. They have compiled 10 saves for the season and have blown 1 of 11 chances to get a save. The relief pitchers have inherited 23 base runners for the season with 26.1% of those runners crossed the plate. The Padres have sent 72 relief pitchers to the mound this season.

The San Diego Padres have earned a total of 582 putouts on the campaign, in addition to 161 assists and 9 errors. Their fielding percentage sits at .988 which ranks 8th in professional baseball, and have accumulated 15 double plays. The Padres have converted 73.9% of balls in play into outs out of their 1,746 innings on the field, ranking them 2nd in professional baseball.

Pivetta (59-72 career record) has a FIP of 4.62 while facing 4,472 opposing batters in the major leagues. He has surrendered 992 hits (8.5 hits per 9 innings) with 382 walks. His ERA is 4.69 (548 ER's allowed) and he has a WHIP of 1.306. Pivetta has taken the ball for 1,052 frames and has earned 1,163 punch outs so far in his career.

Detroit has a total of 22 HRs this year and 96 runs batted in. They have 29 two-baggers, while taking a walk 79 times and putting up 100 runs. The Detroit Tigers have recorded an on-base percentage of .321 as well as a team batting average of .246 over the course of the season. The Tigers hold a team SLG% of .387 and they average 4.55 runs per contest (10th in the league). They have been called out on strikes on 206 occasions (4th in the league) and have earned a total of 182 hits.

The Detroit pitching staff have yielded 76 runs over the course of the season while having a team ERA of 3.12 (67 earned runs relinquished). They have relinquished 22 home runs and they surrender 3.54 runs per 9 innings (3rd in baseball). The Tigers hold a team WHIP of 1.144 with a FIP of 3.88 as a pitching staff so far this year. Their K/BB ratio sits at 8.10 (174 strikeouts against 66 walks). They have a ranking of 7th in baseball as a staff in total hits surrendered with 155.

With 15 save situations, the Tigers have 5 holds in addition to 2 blown saves. Detroit has called on relievers to step onto the mound in 9 save opportunities and they have earned 7 saves. Their relievers have stepped onto the mound 10 times in high leverage situations and on 18 occasions with base runners. Detroit relievers hold an inherited score rate of 20.0% out of their 25 inherited runners. They sit at 6th in MLB holding a save rate of 77.8%, and they have dispatched 62 relief pitchers to the hill on the campaign.

The Detroit Tigers have gotten 11 double plays and own a fielding percentage of .987 (11th in baseball). The Tigers have recorded 185 assists, 10 errors and have notched a total of 580 putouts over the course of the season. Out of their 1,740 innings on the field, the Tigers are sitting with a defensive efficiency of 73.7% (4th in baseball).

During his pro baseball career, Flaherty has conceded 703 base hits while he has totaled 967 strikeouts in 850 innings pitched. Flaherty (56-42 record in his career) has earned a 3.61 ERA and has given up 7.4 hits per nine innings. He has surrendered a total of 341 earned runs while earning a WHIP of 1.181 and a FIP of 3.6. His K/BB ratio is 3.21 and he has gone up against 3,526 opposing hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Detroit (+150)

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