San Diego Padres vs New York Mets Prediction, 9/18/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs New York Mets

Date: Thursday, September 18, 2025

Location: Citi Field in Queens, NY

TV: Sportsnet New York

Odds/Point Spread: San Diego (-144) New York (+120)

The San Diego Padres (82-69) are hitting the road to Citi Field on Thursday where they will take on the New York Mets (78-73). The line on this contest has San Diego at -144 and New York is sitting at +120. The over/under comes in at 8. The pitchers who are expected to start will be Randy Vasquez and Jonah Tong.

San Diego has a slugging percentage of .389 and have struck out 1,071 times, while being walked on 479 occasions. They have amassed 607 RBI's as well as 1,269 base knocks on the year, while their team batting average comes in at .251. The Padres have accumulated 244 two-baggers as a team and have smacked 138 baseballs out of the park. They have racked up 644 runs scored while having a team OBP of .321. As a team, the San Diego Padres are scoring 4.3 runs per outing, which is 23rd in baseball.

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The Padres hold a team ERA of 3.67 on the year (3rd in MLB), and they have struck out 1,323 hitters. Padres pitchers have given up 165 home runs in addition to 586 total runs (2nd in MLB). They have walked 486 opposing players and their FIP is 4.00 as a unit this year. San Diego has relinquished 1,119 hits (7.5 per 9 innings) in addition to 544 earned runs. They have a K/BB ratio of 2.72 and the pitching staff has a collective WHIP of 1.20.

Padres pitchers have come into the game with players on base 171 times in addition to having 197 appearances in high leverage situations. The relievers have earned 96 holds so far this season (6th in baseball). The Padres bullpen have a save percentage of 74.2% and have come into the game in 163 save situations. They have compiled 46 saves on the campaign and have blown 16 of 62 save opportunities. The relief pitchers have inherited 242 runners this year with 29.3% of them ended up scoring. The Padres have dispatched 532 relievers to the mound over the course of the season.

The Padres have turned 71.7% of balls in play into outs in their 12,006 innings on the field, ranking them 2nd in pro baseball. The San Diego Padres are sitting with 4,002 putouts at this point in the season, in addition to 1,138 assists and 70 errors. Their fielding rate is currently at .987 which has them ranked 12th in MLB, and have earned 107 double plays.

Vasquez has taken the ball for 258 frames and has 166 punch outs in his pro baseball career. His earned run average is 4.04 (116 ER's allowed) and his WHIP is 1.401. He has conceded 266 hits (9.3 hits per 9 innings) and has 96 free passes. Vasquez (11-15 career win-loss record) holds a FIP of 3.98 while going up against 1,125 opposing batters in the majors.

The New York Mets have accounted for a team OBP of .327 and a team batting average of .250 so far this year. They have struck out on 1,230 occasions (22nd in baseball) and have notched a total of 1,267 base hits. New York is sitting with 207 home runs on the campaign to go along with 694 RBIs. The Mets have a slugging percentage of .428 and they are scoring 4.72 runs per game (11th in the league). They have hit 246 doubles, while getting a free base 527 times as well as putting up 712 runs.

The Mets are sitting with a team WHIP of 1.334 in addition to having a FIP of 3.91 as a team on the year. Their strikeout to walk ratio is 8.70 (1,291 strikeouts vs 529 walks). They are sitting at 16th in the league as a pitching staff in total hits conceded with 1,250. They have allowed 138 long balls and they concede 4.46 runs per 9 innings (18th in baseball). The New York pitching staff have conceded 661 runs for the season and come in with a team ERA of 4.01 (594 earned runs conceded).

With 157 save situations, the Mets have 92 holds in addition to 27 blown saves. New York has had relief pitchers enter the game in 65 save opportunities and they have earned 38 saves. Their relief pitchers have stepped onto the hill 178 times in high leverage situations and also on 161 occasions with base runners. New York bullpen pitchers hold an inherited score rate of 34.9% out of their 241 inherited base runners. They rank 23rd in MLB with a save rate of 58.5%, and they have dispatched 491 relievers onto the field over the course of the season.

In their 12,006 innings played, the Mets hold a defensive efficiency of 68.8% (24th in pro baseball). The New York Mets have gotten 114 double plays and hold a fielding percentage of .987 (10th in MLB). The Mets have accrued 1,360 assists, 70 errors and have earned a total of 4,002 putouts this season.

Tong (1-2 career win-loss record) is the owner of a 8.84 earned run average and has conceded 10.4 hits per nine innings. He has a strikeout to walk ratio of 1.86 and he has faced 55 opposing batters during his MLB career. He has allowed 11 ER's while earning a WHIP of 1.786 and being the owner of a FIP of 8.7. During his MLB career, Tong has conceded 13 hits and he has 13 strikeouts in 11 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-144)

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