San Diego Padres vs New York Yankees Prediction, 5/7/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs New York Yankees

Date: Wednesday, May 7, 2025

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: San Diego (-182) New York (+150)

The San Diego Padres (23-11) are hitting the road to Yankee Stadium on Wednesday where they will try to defeat the New York Yankees (19-16). The moneyline on this game has the Padres at -182 while the Yankees are coming in at +150. The betting total comes in at 8. The starting pitchers will be Dylan Cease and Max Fried.

The Padres have hit 50 doubles as a unit and have smacked 29 baseballs out of the park. San Diego has a slugging percentage of .393 and have been called out on strikes 226 times, while drawing a walk on 106 occasions. As a squad, the San Diego Padres are notching 4.0 runs per contest, which puts them at 18th in baseball. They have compiled 122 RBI's and 279 hits for the year, and their team batting average is sitting at .260. They are sitting with 133 runs while having a team on-base percentage of .329.

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They have accrued a K/BB ratio of 2.70 and their pitching staff holds a WHIP of 1.14. Padres pitchers have conceded 25 home runs and 95 runs in total (1st in baseball). San Diego has surrendered 225 hits (7.0 per 9 innings) and 89 earned runs. The Padres have a team earned run average of 2.75 for the year (1st in the league), and the staff has struck out 289 hitters. Their pitching staff has walked 107 opposing batters and their FIP sits at 3.43 as a team so far this year.

Padres relief pitchers have entered the game with runners on 25 times in addition to having 43 appearances in high leverage situations. The relievers have recorded 27 holds this year (4th in baseball). The Padres relievers have accumulated a save rate of 93.3% and have come into the game in 43 save situations. They have accumulated 14 saves for the season and have blown 1 of 15 save chances. The bullpen pitchers have inherited 37 runners for the year with 27.0% of them ended up scoring. The Padres have sent 115 relief pitchers to the hill so far this season.

The San Diego Padres have accumulated 873 putouts over the course of the season, in addition to 239 assists and 15 errors. Their fielding percentage sits at .987 which puts them in 13th in the majors, and have a total of 23 double plays. The Padres have transformed 72.5% of balls hit into play into outs out of 2,619 innings on the diamond, which ranks them 4th in pro baseball.

Cease (58-48 career record) holds a FIP of 3.77 and he has gone up against 3,736 opposing batters in the major leagues. He has surrendered 741 base hits (7.6 hits per nine innings) and has had 374 walks. His ERA is 3.82 (374 earned runs allowed) and his WHIP is 1.267. Cease has taken the hill for 880 frames and has earned 1,055 strikeouts in his career.

The Yankees have a team slugging % of .470 and they have an average of 5.50 runs per game (2nd in MLB). They have recorded 59 two-baggers, while taking a walk 135 times as well as earning 187 runs. New York is sitting with 57 long balls so far this year as well as 181 runs batted in. They have been rung up on 308 occasions (5th in baseball) and are sitting with 302 hits. The New York Yankees hold a team on-base percentage of .346 in addition to a team batting average of .262 so far this season.

The Yankees have a WHIP of 1.205 and have a FIP of 3.75 as a unit for the year. They currently have a K/BB ratio of 9.40 (312 strikeouts vs 134 free passes). They are sitting at 1st in MLB as a pitching staff in total hits relinquished with 225. They have relinquished 31 long balls and they give up 4.08 runs per 9 innings (10th in the league). The New York pitching staff have allowed 135 runs so far this year while having an ERA of 3.62 (120 earned runs conceded).

New York has called on bullpen pitchers to step onto the mound in 14 save chances and they have come away with 10 saves. They sit at 11th in baseball with a save rate of 71.4%, and they have dispatched 106 relievers onto the diamond this season. Their relief pitchers have stepped onto the hill 25 times in high leverage situations and on 35 occasions with base runners. New York relievers have an inherited score percentage of 14.3% out of their 49 inherited base runners. Sitting with 35 save situations, the Yankees have recorded 21 holds in addition to 4 blown saves.

The New York Yankees have turned 20 double plays and have a fielding rate of .984 (18th in pro baseball). The Yankees have racked up 286 assists, 19 errors and have notched a total of 894 putouts this season. In 2,682 innings on the diamond, the Yankees have a defensive efficiency of 72.9% (2nd in professional baseball).

During his pro baseball career, Fried has allowed 814 base hits while totaling 902 K's in 928 innings pitched. Fried (79-36 career record) has a 2.98 ERA and has allowed 7.9 hits per nine innings. He has allowed 307 earned runs while holding a WHIP of 1.154 and being the owner of a FIP of 2.9. He has a strikeout to walk ratio of 3.51 and he has gone up against 3,795 opposing hitters during his MLB career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-182)

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