San Diego Padres vs Pittsburgh Pirates Prediction, 5/3/2025 MLB Picks, Best Bets & Odds
Game: San Diego Padres vs Pittsburgh Pirates
Date: Saturday, May 3, 2025
Location: PNC Park in Pittsburgh, PA
TV: SportsNet Pittsburgh
Odds/Point Spread: San Diego (-145) Pittsburgh (+125)
PNC Park is where the Pittsburgh Pirates (12-19) will compete against the San Diego Padres (19-11) on Saturday. The line on this matchup has the Padres at -145 while the Pirates are sitting at +125. The total is set at 8.5. The pitchers taking the mound are Randy Vasquez and Bailey Falter.


The Padres have earned 44 doubles as a team and have hit 26 baseballs out of the stadium. San Diego owns a slugging percentage of .391 and have been called out on strikes 202 times, while being walked on 96 occasions. As a team, the San Diego Padres are putting up 3.9 runs per game, which has them sitting at 20th in the league. They have accrued 109 runs batted in and 252 hits this year, and their batting average comes in at .259. They have racked up 118 runs while holding a team OBP of .327.
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Their strikeout to walk ratio is 2.90 and the pitching staff has a collective WHIP of 1.12. Padres pitchers have given up 24 long balls in addition to 90 runs in total (1st in MLB). San Diego has given up 204 base hits (7.0 per 9 innings) as well as 84 earned runs. The Padres have compiled a team ERA of 2.86 on the season (2nd in MLB), and their staff has rung up 267 batters. Their pitching staff has walked 92 opposing players and their FIP sits at 3.38 as a squad on the season.
The Padres have sent 101 relief pitchers to the hill for the year. The bullpen pitchers have inherited 34 base runners over the course of the season with 29.4% of those players ended up crossing the plate. They have earned 13 saves on the season and have blown 1 out of their 14 save chances. The Padres relievers have recorded a save percentage of 92.9% and have entered the game in 39 save situations. The relief pitchers have earned 25 holds this season (6th in baseball). Padres pitchers have stepped onto the hill with opponents on base 22 times in addition to having 37 appearances in high leverage situations.
The Padres have turned 72.5% of balls in play into outs in their 2,376 innings, which has them ranked 5th in baseball. The San Diego Padres have notched a total of 792 putouts so far this season, as well as 206 assists and 14 errors. Their fielding percentage is at .986 which puts them in 15th in the majors, and they have turned 19 double plays.
Vasquez (7-12 career record) has a FIP of 4.26 while he has gone up against 719 hitters during his time in the major leagues. He has allowed 173 base knocks (9.6 hits per 9 innings) and has 66 walks. His ERA is 4.33 (78 ER's allowed) and he has a WHIP of 1.473. Vasquez has taken the hill for 162 frames and has accounted for 105 K's in his career.
The Pittsburgh Pirates have an OBP of .305 as well as a team batting average of .226 this season. They have been rung up on 274 occasions (6th in baseball) and have earned 233 hits. Pittsburgh has 23 home runs on the season to go along with 104 RBIs. The Pirates hold a slugging % of .340 and they are scoring 3.42 runs per game (26th in MLB). They have put up 39 doubles, while walking 109 times and putting up 106 runs.
The Pittsburgh pitching staff have given up 139 runs over the course of the season while having a team ERA of 4.11 (127 earned runs surrendered). They have yielded 26 long balls and they allow 4.50 runs per 9 innings (19th in the league). The Pirates hold a team WHIP of 1.237 and are the owners of a FIP of 3.77 as a unit so far this season. They currently have a strikeout to walk ratio of 7.60 (235 strikeouts against 95 walks). They are sitting at 19th in the league as a staff in total hits relinquished with 249.
Pittsburgh has had relievers take the mound in 12 save opportunities and they have recorded 7 saves. They rank 20th in the league with a save percentage of 58.3%, and they have dispatched 104 relief pitchers to the mound on the season. Their relief pitchers have stepped onto the mound 36 times in high leverage situations and on 31 occasions with runners on. Pittsburgh bullpen pitchers have an inherited score percentage of 32.7% out of their 49 inherited runners. With 31 save situations, the Pirates have earned 19 holds in addition to 5 blown saves.
In their 2,505 innings on the field, the Pirates have earned a defensive efficiency of 70.2% (14th in professional baseball). The Pittsburgh Pirates have turned 27 double plays and hold a fielding percentage of .979 (26th in MLB). The Pirates have recorded 285 assists, 24 errors and have earned 835 putouts for the year.
During his MLB career, Falter has surrendered 383 base hits and he has 287 strikeouts in 370 frames. Falter (19-26 record in his career) has a 4.74 earned run average and has surrendered 9.3 hits per 9 innings. He has conceded 195 earned runs while earning a WHIP of 1.296 and having a FIP of 4.7. His strikeout to walk ratio is 2.96 and he has faced 1,551 opposing batters during his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take Pittsburgh (+125)
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Additional Resources:
Pittsburgh Pirates - Twitter
San Diego Padres - Twitter