San Diego Padres vs Toronto Blue Jays Prediction, 5/22/2025 MLB Picks, Best Bets & Odds

Game: San Diego Padres vs Toronto Blue Jays

Date: Thursday, May 22, 2025

Location: Rogers Centre in Toronto, ON

TV: Sportsnet

Odds/Point Spread: San Diego (-182) Toronto (+150)

The Toronto Blue Jays (23-24) are welcoming the San Diego Padres (27-19) at Rogers Centre on Thursday. The moneyline on this game has the Padres at -182 while the Blue Jays are priced at +150. The total is 8. The men taking the mound are Stephen Kolek and Bowden Francis.

San Diego owns a slugging percentage of .392 and have been rung up 316 times, while drawing a walk on 145 occasions. They have compiled 181 RBI's as well as 396 hits on the campaign, and their team batting average is sitting at .259. The Padres have accounted for 67 two-baggers as a unit and have smacked 41 baseballs out of the park. They have a total of 199 runs while having a team on-base percentage of .326. As a squad, the San Diego Padres are knocking in 4.3 runs per game, which is 13th in the league.

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They have a strikeout to walk ratio of 2.72 and the pitching staff sits with a WHIP of 1.16. Padres pitchers have surrendered 48 home runs and 164 runs (4th in MLB). San Diego has given up 322 base hits (7.2 per 9 innings) and also 153 earned runs. The Padres have an earned run average of 3.39 this season (8th in MLB), and the staff has struck out 405 hitters. Their pitching staff has walked 149 opposing batters and their FIP is 3.83 as a unit on the year.

Padres relief pitchers have come into the game with runners on base 42 times in addition to having 57 appearances in high leverage situations. The relief pitchers have notched 33 holds for the season (7th in baseball). The Padres relief pitchers have a save percentage of 80.0% and have entered the game in 54 save situations. They have compiled 16 saves so far this season and have blown 4 of 20 chances to save the game. The relief pitchers have inherited 62 base runners for the season and 35.5% of them crossed the plate. The Padres have sent 157 relievers to the mound so far this season.

The San Diego Padres are sitting with 1,217 putouts this year, as well as 331 assists and 22 errors. Their fielding percentage sits at .986 which ranks 16th in professional baseball, and they have turned 34 double plays. The Padres have turned 72.7% of balls hit into play into outs in their 3,651 innings on the field, which has them sitting at 2nd in pro baseball.

Kolek has thrown 65 innings and is sitting with 54 punch outs during his MLB career. His earned run average is 4.41 (32 earned runs allowed) and his WHIP is 1.424. He has conceded 76 base hits (10.5 hits per 9 innings) and has had 17 walks. Kolek (5-1 win-loss mark in his career) sits with a FIP of 4.34 and he has gone up against 286 batters in the majors.

Toronto has hit 42 long balls on the season as well as 176 runs batted in. They have recorded 80 two-baggers, while getting a free base 149 times and notching 182 runs. The Toronto Blue Jays are sitting with a team OBP of .316 in addition to a team batting average of .247 on the season. The Blue Jays have a team SLG% of .379 and they average 3.87 runs per contest (23rd in baseball). They have struck out on 350 occasions (28th in MLB) and have 388 hits.

The Blue Jays have a team WHIP of 1.235 with a FIP of 4.30 as a team for the year. Their K/BB ratio sits at 9.20 (432 strikeouts vs 140 walks). They come in at 11th in baseball as a pitching staff in total hits surrendered with 379. They have relinquished 68 dingers and they concede 4.43 runs per 9 innings (18th in baseball). The Toronto pitching staff have allowed 207 runs on the campaign while holding a team ERA of 4.22 (197 earned runs conceded).

With 51 save situations, the Blue Jays have compiled 27 holds in addition to 9 blown saves. Toronto has called on relievers to step onto the mound in 24 save opportunities and they have earned 15 saves. Their bullpen pitchers have stepped onto the hill 43 times in high leverage situations and on 53 occasions with base runners. Toronto relief pitchers have an inherited score rate of 20.8% out of their 72 inherited base runners. They are currently ranked 19th in baseball with a save rate of 62.5%, and they have dispatched 161 relievers to the hill on the campaign.

The Toronto Blue Jays have turned 32 double plays and hold a fielding percentage of .987 (11th in pro baseball). The Blue Jays have 368 assists, 22 errors and have a tally of 1,262 putouts so far this year. In 3,786 innings played, the Blue Jays hold a defensive efficiency of 70.4% (12th in professional baseball).

So far in his MLB career, Francis has conceded 149 base knocks while he has earned 164 K's in 186 innings. Francis (11-11 career record) has a 3.57 earned run average while giving up 7.2 hits per 9 innings. He has allowed a total of 74 earned runs while holding a WHIP of 1.031 and being the owner of a FIP of 3.5. He has a strikeout to walk ratio of 3.81 and he has faced 748 hitters thus far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take San Diego (-182)

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