San Francisco Giants vs Chicago White Sox Prediction, 6/27/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Chicago White Sox

Date: Friday, June 27, 2025

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: San Francisco (-145) Chicago (+125)

Rate Field is where the Chicago White Sox (26-55) will attempt to beat the San Francisco Giants (44-36) on Friday. The moneyline on this game has the Giants at -145 while the White Sox are priced at +125. The over/under is set at 9. The expected starting pitchers will be Landen Roupp and Aaron Civale.

The Giants have recorded 114 two-baggers as a squad and have knocked 78 balls out of the park. San Francisco has a slugging % of .373 and have been rung up 670 times, while taking a walk on 288 occasions. As a team, the San Francisco Giants are scoring 4.2 runs per outing, which ranks them 15th in baseball. They have 320 runs batted in and 604 base knocks so far this year, and their average at the plate is .231. They have accounted for 339 runs and hold an on-base percentage of .312.

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The Giants have a team ERA of 3.31 over the course of the season (3rd in the league), and the staff has struck out 688 batters. Giants pitchers have allowed 62 home runs and 298 total runs (5th in the league). Their pitching staff has walked 249 players from the other team and their FIP comes in at 3.43 as a squad on the campaign. San Francisco has surrendered 623 base hits (7.9 per 9 innings) as well as 261 earned runs. Their K/BB ratio is 2.76 and the pitching staff has earned a collective WHIP of 1.23.

Giants bullpen pitchers have gone to the mound with runners on 56 times in addition to having 95 appearances in high leverage situations. The relievers are sitting with 57 holds this season (4th in the league). The Giants relievers have earned a save rate of 65.7% and have come into the game in 92 save situations. They have accumulated 23 saves over the course of the season and have blown 12 of their 35 save chances. The relievers have inherited 90 runners so far this year with 31.1% of them ended up crossing the plate. The Giants have dispatched 250 relief pitchers to the hill so far this year.

The Giants have transformed 69.5% of balls in play into outs in their 6,378 innings on the field, which has them sitting at 18th in the majors. The Seattle Mariners have a tally of 2,126 putouts at this point in the season, in addition to 756 assists and 44 errors. Their fielding rate is at .985 which has them ranked 21st in the majors, and they have turned 57 double plays.

Roupp has taken the ball for 126 innings and is sitting with 117 K's during his pro baseball career. His ERA is 3.64 (51 ER's allowed) and his career WHIP is 1.404. He has conceded 119 hits (8.5 hits per nine innings) and has 58 free passes. Roupp (6-7 career record) has a FIP of 3.59 and he has gone up against 550 hitters during his time in the major leagues.

The Chicago White Sox have accounted for an on-base percentage of .293 as well as a batting average of .220 on the year. They have been rung up on 707 instances (6th in MLB) and have recorded 583 hits. Chicago has compiled 64 home runs for the season as well as 267 runs batted in. The White Sox hold a team slugging percentage of .345 and they earn 3.46 runs per contest (28th in the league). They have hit 123 two-baggers, while taking a walk 266 times and racking up 280 runs.

The White Sox have a team WHIP of 1.403 with a FIP of 4.50 as a unit this year. They currently have a strikeout to walk ratio of 7.50 (584 strikeouts vs 293 bases on balls). They have a ranking of 23rd in the league as a staff in total hits conceded with 692. They have conceded 88 dingers and they give up 4.64 runs per 9 innings (23rd in MLB). The Chicago pitching staff have conceded 362 runs on the campaign while holding an ERA of 4.18 (326 earned runs relinquished).

Sitting with 61 save situations, the White Sox have tallied 39 holds in addition to 14 blown saves. Chicago has had relievers enter the game in 22 save chances and they have recorded 8 saves. Their relievers have taken the field 73 times in high leverage situations and on 77 occasions with runners on. Chicago relief pitchers have an inherited score rate of 27.9% out of 111 inherited runners. They rank 30th in the league with a save rate of 36.4%, and they have sent 259 relievers onto the diamond so far this season.

In their 6,321 innings on the field, the White Sox hold a efficiency on defense of 69.1% (20th in baseball). The Chicago White Sox have turned 67 double plays and have a fielding rate of .981 (27th in professional baseball). The White Sox have accrued 666 assists, 53 errors and have earned 2,107 putouts for the year.

So far in his pro baseball career, Civale has surrendered 632 hits while he has tallied 602 punch outs in 670 frames. Civale (40-39 career mark) has earned a 4.08 earned run average while allowing 8.5 hits per nine innings. He has given up a total of 304 earned runs while earning a WHIP of 1.215 and being the owner of a FIP of 4.0. His strikeout to walk ratio is 3.31 and he has gone up against 2,786 opposing batters so far in his career.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+125)

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