San Francisco Giants vs Houston Astros Prediction, 4/1/2025 MLB Picks, Best Bets & Odds
Game: San Francisco Giants vs Houston Astros
Date: Tuesday, April 1, 2025
Location: Daikin Park in Houston, TX
TV: Space City Home Network
Odds/Point Spread: San Francisco (+120) Houston (-144)
Daikin Park is where the Houston Astros (2-1) will try to beat the San Francisco Giants (2-1) on Tuesday. The moneyline on this contest has San Francisco at +120 while Houston is sitting at -144. The over/under has been set at 8. The expected starting pitchers will be Logan Webb and Hayden Wesneski.


As a team, the San Francisco Giants are scoring 4.7 runs per game, which has them at 9th in MLB. They have earned 14 runs while holding a team on-base percentage of .250. The Giants have tallied 4 doubles as a squad and have hit 5 baseballs out of the park. They have 14 runs batted in and 21 base knocks on the year, while their team batting average comes in at .214. San Francisco has a slugging rate of .408 and have been called out on strikes 25 times, while being walked on 4 occasions.
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Their strikeout to walk ratio sits at 3.14 and their pitching staff has earned a collective WHIP of 1.08. Giants pitchers have yielded 4 home runs in addition to 10 runs (11th in the league). San Francisco has allowed 21 hits (7.3 per 9 innings) and also 10 earned runs. The Giants have an earned run average of 3.46 so far this year (16th in MLB), and the staff has rung up 22 hitters. They have walked 7 opposing hitters and their FIP sits at 3.86 as a team on the campaign.
The Giants bullpen have accumulated a save rate of 100.0% and has come into the game in 5 save situations. The relievers have inherited 1 runner on the year and none of them crossed home plate. Giants relief pitchers have entered the game with players on base 1 time in addition to having 2 appearances in high leverage situations. The Giants have dispatched 11 relievers to the mound for the season. The relief pitchers have racked up 3 holds on the year (15th in baseball). They have 2 saves so far this season.
The Giants have turned 75.4% of balls in play into outs out of 234 innings, which has them sitting at 8th in professional baseball. The Seattle Mariners have accounted for 78 putouts so far this season, in addition to 24 assists and 0 errors. Their fielding percentage is currently at 1.000 which ranks 1st in baseball, and they have turned 3 double plays.
Webb has taken the ball for 855 innings and has accounted for 770 strikeouts during his MLB career. Webb (55-42 win-loss mark in his career) holds a FIP of 3.37 while he has gone up against 3,494 batters during his time in the majors. His ERA is 3.42 (325 earned runs allowed) and his WHIP is 1.186. He has conceded 810 base knocks (8.5 hits per nine innings) and has 204 free passes.
The Houston Astros are sitting with an OBP of .290 as well as a team batting average of .176 so far this season. They have struck out on 23 occasions (20th in baseball) and have totaled 15 hits. Houston has accumulated 1 home run on the year to go along with 5 runs batted in. The Astros hold a slugging percentage of .224 and they score 2.00 runs per game (25th in baseball). They have recorded 1 double, while taking a walk 13 times as well as notching 6 runs.
The Astros hold a team WHIP of 0.926 and have a FIP of 2.78 as a staff for the season. Their strikeout to walk ratio is 9.00 (27 strikeouts vs 13 walks). They are sitting at 1st in baseball as a pitching staff in total hits surrendered with 12. They have conceded 1 home run and they allow 1.67 runs per 9 innings (2nd in MLB). The Houston pitching staff have surrendered 5 runs for the season while having an ERA of 1.33 (4 earned runs conceded).
Sitting with 5 save situations, the Astros have accumulated 3 holds and also 0 blown saves. Houston has called on relief pitchers to step onto the mound in 2 save chances and they have tallied 2 saves. Their bullpen pitchers have stepped onto the mound 3 times in high leverage situations and also on 1 occasion with runners on. Houston relief pitchers hold an inherited score rate of 0.0% of 2 inherited base runners. They are ranked 2nd in the league with a save percentage of 100.0%, and they have sent 9 relief pitchers onto the field so far this season.
The Houston Astros have gotten 3 double plays and have accounted for a fielding rate of .991 (14th in pro baseball). The Astros have recorded 28 assists, 1 error and have amassed 81 putouts on the season. Out of their 243 innings played, the Astros are sitting with a defensive efficiency of 81.1% (2nd in MLB).
During his MLB career, Wesneski has surrendered 162 hits while earning 183 strikeouts in 190 frames. Wesneski (9-13 win-loss mark in his career) has a 3.93 ERA while surrendering 7.7 hits per 9 innings. He has surrendered a total of 83 ER's while holding a WHIP of 1.168 and having a FIP of 3.9. His K/BB ratio is 3.05 and he has faced 794 opposing batters so far in his career.
Who will win tonight's MLB game against the spread or moneyline?
Tony Sink's Pick: Take San Francisco (+120)
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Additional Resources:
Houston Astros - Twitter
San Francisco Giants - Twitter