San Francisco Giants vs Los Angeles Dodgers Prediction, 9/19/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Los Angeles Dodgers

Date: Friday, September 19, 2025

Location: Dodger Stadium in Los Angeles, CA

TV: Spectrum SportsNet LA

Odds/Point Spread: San Francisco (+102) Los Angeles (-122)

The San Francisco Giants (76-76) are on their way to Dodger Stadium on Friday where they will play the Los Angeles Dodgers (85-67). The odds on this game have the Giants at +102 while the Dodgers are at -122. The over/under has been set at 8.5. The expected starting pitchers will be Robbie Ray and Clayton Kershaw.

As a squad, the San Francisco Giants are scoring 4.4 runs per outing, which ranks them 17th in the league. They are sitting with 662 runs while holding a team OBP of .311. The Giants have tallied 225 doubles as a team and have hit 162 balls out of the stadium. They have 632 RBI's and 1,192 hits for the year, and their team batting average is .236. San Francisco is slugging .387 and have struck out 1,289 times, while drawing a walk on 511 occasions.

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They have accumulated a K/BB ratio of 2.63 and their pitching staff has a collective WHIP of 1.31. Giants pitchers have yielded 129 home runs in addition to 644 total runs (12th in baseball). San Francisco has surrendered 1,276 hits (8.5 per 9 innings) and also 575 earned runs. The Giants have a team earned run average of 3.84 so far this year (9th in baseball), and the staff has rung up 1,270 hitters. They have walked 482 opposing hitters and their FIP sits at 3.73 as a team so far this season.

The Giants have sent 484 relievers to the mound on the season. The relief pitchers have inherited 181 base runners this year and 37.6% of them crossed home plate. They have 36 saves for the year and have blown 19 out of their 55 save opportunities. The Giants bullpen have accumulated a save percentage of 65.5% and have entered the game in 134 save situations. The bullpen have a total of 79 holds for the year (20th in MLB). Giants bullpen pitchers have gone to the mound with runners on base 115 times and also have had 162 appearances in high leverage situations.

The Seattle Mariners have notched a total of 4,040 putouts thus far, as well as 1,426 assists and 90 errors. Their fielding percentage is holding at .984 which is 25th in pro baseball, and they have turned 125 double plays. The Giants have turned 68.2% of baseballs in play into outs out of their 12,120 innings on the field, ranking them 27th in pro baseball.

Ray (88-80 career win-loss record) sits with a FIP of 3.87 and he has faced 6,077 batters in the major leagues. He has allowed 1,245 hits (7.8 hits per 9 innings) with 606 walks. His ERA is 3.93 (626 earned runs allowed) and his WHIP is 1.290. Ray has taken the hill for 1,435 innings and has accounted for 1,729 punch outs so far in his MLB career.

The Los Angeles Dodgers have compiled an OBP of .330 as well as a team batting average of .254 this year. They have been rung up on 1,267 instances (15th in the league) and are sitting with 1,308 base hits. Los Angeles has compiled 225 home runs on the season to go along with 746 runs batted in. The Dodgers have a team SLG% of .440 and they score 5.12 runs per outing (3rd in the league). They have put up 242 doubles, while taking a walk 556 times as well as scoring 778 runs.

The Los Angeles pitching staff have surrendered 656 runs on the campaign and come in with a team ERA of 4.05 (607 earned runs relinquished). They have given up 171 long balls and they yield 4.38 runs per 9 innings (15th in the league). The Dodgers are sitting with a team WHIP of 1.265 and have a FIP of 4.04 as a squad so far this season. Their strikeout to walk ratio comes in at 9.20 (1,383 strikeouts vs 523 bases on balls). They come in at 4th in the league as a staff in total hits conceded with 1,184.

With 179 save situations, the Dodgers have 111 holds in addition to 24 blown saves. Los Angeles has called on relievers to step onto the mound in 63 save opportunities and they have come away with 39 saves. Their relievers have come in 165 times in high leverage situations and also on 138 occasions with runners on base. Los Angeles relief pitchers have an inherited score percentage of 26.0% out of their 215 inherited base runners. They rank 17th in the league with a save percentage of 61.9%, and they have sent 538 bullpen pitchers to the mound for the season.

The Los Angeles Dodgers have turned 97 double plays and have a fielding percentage of .988 (6th in the majors). The Dodgers have 1,272 assists, 64 errors and have earned 4,048 putouts over the course of the season. Out of their 12,144 innings on the diamond, the Dodgers have a defensive efficiency of 70.4% (10th in professional baseball).

Kershaw (222-96 career mark) has a 2.54 earned run average and has given up 6.9 hits per 9 innings. He has a K/BB ratio of 4.29 and he has faced 11,234 batters during his MLB career. He has allowed a total of 802 earned runs while holding a WHIP of 1.017 and having a FIP of 2.5. In his MLB career, Kershaw has given up 2,185 base hits while he has totaled 3,039 strikeouts in 2,844 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Los Angeles (-122) and under 8.5 runs

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