San Francisco Giants vs Los Angeles Dodgers Prediction, 9/20/2025 MLB Picks, Best Bets & Odds

Game: San Francisco Giants vs Los Angeles Dodgers

Date: Saturday, September 20, 2025

Location: Dodger Stadium in Los Angeles, CA

TV: Spectrum SportsNet LA

Odds/Point Spread: San Francisco (+162) Los Angeles (-196)

The San Francisco Giants (76-76) are on their way to Dodger Stadium on Saturday where they will try to beat the Los Angeles Dodgers (85-67). The moneyline on this contest has San Francisco at +162 while Los Angeles is priced at -196. The over/under has been set at 8.5. The starting pitchers will be Kai-Wei Teng and Tyler Glasnow.

As a team, the San Francisco Giants are putting up 4.4 runs per game, which is 17th in MLB. They have racked up 662 runs while holding a team OBP of .311. The Giants have earned 225 doubles as a squad and have hit 162 baseballs out of the park. They have earned 632 runs batted in and 1,192 hits on the season, while their team batting average is .236. San Francisco has a slugging percentage of .387 and have been called out on strikes 1,289 times, while drawing a walk on 511 occasions.

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They have a K/BB ratio of 2.63 and the pitching staff has earned a collective WHIP of 1.31. Giants pitchers have surrendered 129 home runs and 644 runs in total (12th in MLB). San Francisco has surrendered 1,276 hits (8.5 per 9 innings) and 575 earned runs. The Giants are sitting with a team ERA of 3.84 over the course of the season (9th in baseball), and the staff has struck out 1,270 hitters. Their pitching staff has walked 482 opposing hitters and their FIP comes in at 3.73 as a team this season.

The Giants relievers have earned a save percentage of 65.5% and have come into the game in 134 save situations. The relief pitchers have inherited 181 base runners on the campaign with 37.6% of those runners ended up crossing the plate. Giants relief pitchers have stepped onto the hill with runners on base 115 times and also have had 162 appearances in high leverage situations. The Giants have dispatched 484 relief pitchers to the hill so far this year. The relief pitchers have a total of 79 holds on the year (20th in the league). They have compiled 36 saves for the season and have blown 19 of their 55 chances to get a save.

The Giants have converted 68.2% of baseballs in play into outs in their 12,120 innings on the diamond, which has them ranked 27th in MLB. The Seattle Mariners have notched a total of 4,040 putouts over the course of the season, as well as 1,426 assists and 90 errors. Their fielding percentage is currently at .984 which has them sitting 25th in the majors, and they have turned 125 double plays.

Teng (2-4 career mark) has earned a FIP of 7.39 while he has faced 179 batters in the major leagues. He has given up 43 base hits (10.4 hits per nine innings) with 23 walks. His ERA is 7.50 (31 ER's allowed) and he has a career WHIP of 1.774. Teng has pitched in 37 innings and is sitting with 40 punch outs during his pro baseball career.

The Dodgers hold a slugging % of .440 and they are earning 5.12 runs per game (3rd in baseball). They have tallied 242 two-baggers, while walking 556 times and putting up 778 runs. Los Angeles has a total of 225 HRs for the year to go along with 746 RBIs. They have struck out on 1,267 instances (15th in the league) and are sitting with 1,308 base hits. The Los Angeles Dodgers have a team on-base percentage of .330 as well as a team batting average of .254 for the year.

The Dodgers have a team WHIP of 1.265 in addition to having a FIP of 4.04 as a staff this season. Their strikeout to walk ratio sits at 9.20 (1,383 strikeouts vs 523 free passes). They come in at 4th in MLB as a pitching staff in total hits surrendered with 1,184. They have surrendered 171 homers and they yield 4.38 runs per 9 innings (15th in baseball). The Los Angeles pitching staff have surrendered 656 runs on the year while having a team ERA of 4.05 (607 earned runs relinquished).

Los Angeles has had relief pitchers step onto the hill in 63 save opportunities and they have earned 39 saves. They rank 17th in MLB holding a save percentage of 61.9%, and they have sent 538 relievers to the mound so far this year. Their relief pitchers have taken the field 165 times in high leverage situations in addition to 138 occasions with runners on. Los Angeles bullpen pitchers have an inherited score percentage of 26.0% out of their 215 inherited runners. Sitting with 179 save situations, the Dodgers have earned 111 holds and 24 blown saves.

Out of their 12,144 innings played, the Dodgers have a efficiency on defense of 70.4% (10th in MLB). The Los Angeles Dodgers have gotten 97 double plays and have a fielding rate of .988 (6th in baseball). The Dodgers have accrued 1,272 assists, 64 errors and have earned 4,048 putouts on the campaign.

So far in his career, Glasnow has conceded 566 base hits while he has earned 942 strikeouts in 745 frames. Glasnow (42-36 mark in his career) has earned a 3.73 earned run average and has surrendered 6.8 hits per nine innings. He has allowed 309 ER's while holding a WHIP of 1.142 and being the owner of a FIP of 3.7. His K/BB ratio is 3.31 and he has gone up against 3,048 opposing hitters during his career.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Los Angeles (-196) and under 8.5 runs

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