San Francisco Giants vs Minnesota Twins Prediction, 5/10/2025 MLB Picks, Best Bets & Odds
Game: San Francisco Giants vs Minnesota Twins
Date: Saturday, May 10, 2025
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: San Francisco (-160) Minnesota (+132)
Target Field is the location where the Minnesota Twins (17-20) will meet the San Francisco Giants (24-14) on Saturday. The odds on this game have the Giants at -160 and the Twins are at +132. The over/under is set at 9. The starting pitchers are Logan Webb and Chris Paddack.


As a team, the San Francisco Giants are knocking in 4.8 runs per contest, which ranks them 9th in the league. They have earned a total of 183 runs scored while holding a team on-base percentage of .314. The Giants have accumulated 63 two-baggers as a team and have knocked 39 balls out of the park. They have accounted for 174 runs batted in as well as 298 hits on the year, and their average at the plate sits at .236. San Francisco has a slugging rate of .387 and have been rung up 326 times, while being walked on 135 occasions.
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They have accumulated a K/BB ratio of 2.67 and the pitching staff has recorded a WHIP of 1.22. Giants pitchers have yielded 28 home runs and 144 total runs (9th in baseball). San Francisco has yielded 286 hits (7.7 per 9 innings) in addition to 126 earned runs. The Giants have a team ERA of 3.39 on the year (6th in the league), and the staff has struck out 329 batters. They have walked 123 opposing hitters and their FIP sits at 3.42 as a team on the campaign.
The Giants bullpen have a save percentage of 66.7% and have stepped onto the mound in 45 save situations. The relievers have inherited 42 base runners for the year and 40.5% of them crossed the plate. Giants pitchers have come into the game with runners on base 23 times in addition to having 39 appearances in high leverage situations. The Giants have sent 115 relievers to the hill over the course of the season. The relievers have racked up 27 holds so far this season (8th in baseball). They have earned 12 saves on the campaign and have not converted 6 of 18 save chances.
The Giants have turned 69.8% of baseballs in play into outs in their 3,009 innings, which ranks them 16th in pro baseball. The Seattle Mariners have earned a total of 1,003 putouts on the year, in addition to 368 assists and 21 errors. Their fielding percentage is holding steady at .985 which puts them in 16th in professional baseball, and they have turned 33 double plays.
Webb (59-44 career record) has a FIP of 3.33 while facing 3,689 opposing batters in the major leagues. He has conceded 855 base knocks (8.5 hits per 9 innings) with 217 free passes. His ERA is 3.38 (339 earned runs allowed) and he has a career WHIP of 1.187. Webb has taken the hill for 903 innings and has earned 826 K's so far in his career.
The Minnesota Twins have tallied an on-base percentage of .307 and a batting average of .238 so far this year. They have been rung up on 293 occasions (19th in the league) and have a total of 292 base hits. Minnesota has compiled 32 long balls so far this year to go along with 141 runs batted in. The Twins have a SLG% of .374 and they average 3.97 runs per game (20th in MLB). They have tallied 63 doubles, while walking 104 times and earning 147 runs.
The Twins have a WHIP of 1.203 and are the owners of a FIP of 3.59 as a unit on the season. Their K/BB ratio comes in at 9.20 (327 strikeouts against 94 free passes). They rank 13th in the league as a pitching staff in total hits allowed with 291. They have allowed 37 homers and they give up 3.80 runs per 9 innings (6th in the league). The Minnesota pitching staff have given up 135 runs on the year while having an ERA of 3.49 (124 earned runs surrendered).
Minnesota has had relief pitchers take the mound in 12 save chances and they have come away with 6 saves. They are currently ranked 27th in baseball holding a save percentage of 50.0%, and they have dispatched 127 bullpen pitchers to the mound for the season. Their relief pitchers have stepped onto the hill 40 times in high leverage situations in addition to 29 occasions with runners on. Minnesota bullpen pitchers have an inherited score rate of 36.4% of 44 inherited runners. With 42 save situations, the Twins have compiled 29 holds in addition to 6 blown saves.
In their 2,883 innings played, the Twins have earned a defensive efficiency of 69.2% (20th in pro baseball). The Minnesota Twins have gotten 20 double plays and own a fielding percentage of .983 (23rd in pro baseball). The Twins have racked up 255 assists, 21 errors and have accumulated 961 putouts during this campaign.
Paddack (27-27 mark in his career) has earned a 4.47 ERA while allowing 8.8 hits per 9 innings. His strikeout to walk ratio is 4.20 and he has faced 1,916 opposing hitters so far in his pro baseball career. He has allowed a total of 226 earned runs while holding a WHIP of 1.212 and a FIP of 4.4. In his pro baseball career, Paddack has allowed 447 base knocks while earning 441 K's in 455 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Minnesota (+132)
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Additional Resources:
Minnesota Twins - Twitter
San Francisco Giants - Twitter