San Francisco Giants vs Minnesota Twins Prediction, 5/11/2025 MLB Picks, Best Bets & Odds
Game: San Francisco Giants vs Minnesota Twins
Date: Sunday, May 11, 2025
Location: Target Field in Minneapolis, MN
TV: Twins.TV
Odds/Point Spread: San Francisco (-132) Minnesota (+110)
The Minnesota Twins (18-20) are welcoming the San Francisco Giants (24-14) at Target Field on Sunday. The moneyline on this game has San Francisco at -132 and Minnesota is priced at +110. The betting total comes in at 8. The pitchers who are expected to start are Landen Roupp and Pablo Lopez.


San Francisco has a slugging percentage of .387 and have been called out on strikes 326 times, while being walked on 135 occasions. They have compiled 174 runs batted in and 298 base knocks this year, while their average at the plate is sitting at .236. The Giants have tallied 63 two-baggers as a team and have hit 39 balls out of the park. They have a total of 183 runs while holding a team OBP of .314. As a team, the San Francisco Giants are putting up 4.8 runs per contest, which is 9th in MLB.
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The Giants have a team ERA of 3.39 this year (6th in the league), and the staff has struck out 329 hitters. Giants pitchers have allowed 28 long balls and also 144 runs in total (8th in baseball). Their pitching staff has walked 123 opposing batters and their FIP is 3.44 as a team this season. San Francisco has conceded 286 hits (7.7 per 9 innings) and 126 earned runs. They have accrued a K/BB ratio of 2.67 and their pitching staff has a collective WHIP of 1.22.
The Giants relievers have a save rate of 66.7% and have stepped onto the mound in 45 save situations. The bullpen pitchers have inherited 42 base runners on the year with 40.5% of those runners ended up crossing the plate. Giants pitchers have come into the game with runners on 23 times in addition to having 39 appearances in high leverage situations. The Giants have dispatched 115 relief pitchers to the hill on the year. The relief pitchers have notched 27 holds for the year (8th in the league). They have earned 12 saves for the year and have blown 6 of 18 chances to save the game.
The Giants have converted 69.8% of balls hit into play into outs out of 3,009 innings, which has them ranked 15th in the majors. The Seattle Mariners have amassed 1,003 putouts on the year, in addition to 368 assists and 21 errors. Their fielding percentage is currently at .985 which is 15th in MLB, and have 33 double plays.
Roupp has taken the ball for 85 frames and has 86 punch outs thus far in his career. His ERA is 4.12 (39 ER's allowed) and his WHIP is 1.445. He has given up 83 base hits (8.8 hits per nine innings) with 40 free passes. Roupp (3-5 career record) sits with a FIP of 4.06 and he has gone up against 374 hitters in the major leagues.
Minnesota has knocked in 33 HRs so far this season as well as 146 RBIs. They have 64 two-baggers, while taking a walk 109 times as well as scoring 152 runs. The Minnesota Twins hold an on-base percentage of .307 in addition to a team batting average of .237 for the season. The Twins have a team slugging percentage of .373 and they are earning 4.00 runs per game (20th in baseball). They have struck out on 304 instances (17th in MLB) and have a total of 297 base hits.
The Twins are sitting with a team WHIP of 1.203 and have a FIP of 3.54 as a team for the season. They currently have a K/BB ratio of 9.20 (338 strikeouts vs 95 free passes). They sit at 15th in MLB as a staff in total hits conceded with 301. They have surrendered 37 long balls and they yield 3.75 runs per 9 innings (6th in MLB). The Minnesota pitching staff have conceded 137 runs so far this year while having an ERA of 3.42 (125 earned runs surrendered).
Minnesota has had relievers enter the game in 13 save opportunities and they have tallied 7 saves. They are currently ranked 24th in the league holding a save rate of 53.8%, and they have dispatched 131 relief pitchers to the hill for the season. Their relief pitchers have come in 42 times in high leverage situations in addition to 29 occasions with runners on base. Minnesota relievers have an inherited score percentage of 36.4% out of their 44 inherited runners. With 43 save situations, the Twins have compiled 29 holds in addition to 6 blown saves.
The Minnesota Twins have turned 21 double plays and have a fielding rate of .983 (23rd in the majors). The Twins have racked up 263 assists, 22 errors and have notched a total of 988 putouts for the year. In their 2,964 innings played, the Twins have a efficiency on defense of 68.9% (20th in professional baseball).
During his career, Lopez has given up 845 base hits while earning 958 K's in 922 innings. Lopez (57-51 career mark) is the owner of a 3.85 ERA while allowing 8.2 hits per nine innings. He has allowed 394 ER's while earning a WHIP of 1.172 and a FIP of 3.8. He has a strikeout to walk ratio of 4.06 and he has gone up against 3,813 opposing batters so far in his MLB career.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Minnesota (+110)
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Additional Resources:
Minnesota Twins - Twitter
San Francisco Giants - Twitter