Seattle Mariners vs Chicago White Sox Prediction, 5/20/2025 MLB Picks, Best Bets & Odds

Game: Seattle Mariners vs Chicago White Sox

Date: Tuesday, May 20, 2025

Location: Rate Field in Chicago, IL

TV: Chicago Sports Network

Odds/Point Spread: Seattle (-128) Chicago (+106)

The Seattle Mariners (26-19) are en route to Rate Field on Tuesday where they will attempt to beat the Chicago White Sox (14-33). The moneyline on this matchup has the Mariners at -128 and the White Sox are opening at +106. The betting total comes in at 8. The pitchers who are expected to start will be Jhonathan Diaz and Bryse Wilson.

The Mariners have tallied 59 two-baggers as a team and have hit 62 balls out of the park. Seattle is slugging .402 and have been called out on strikes 404 times, while taking a walk on 179 occasions. As a team, the Seattle Mariners are notching 4.8 runs per contest, which ranks them 7th in the league. They have accumulated 208 RBI's as well as 363 hits this year, and their average at the plate is sitting at .238. They have earned 216 runs and hold an on-base percentage of .326.

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The Mariners have an ERA of 3.72 this year (11th in baseball), and the staff has rung up 372 batters. Mariners pitchers have conceded 44 long balls in addition to 193 total runs (15th in MLB). Their pitching staff has walked 148 opposing hitters and their FIP sits at 3.84 as a squad on the year. Seattle has yielded 394 base knocks (8.6 per 9 innings) and also 170 earned runs. They have a strikeout to walk ratio of 2.51 and the pitching staff has recorded a WHIP of 1.32.

The Mariners have dispatched 160 relief pitchers to the hill for the year. The relief pitchers have inherited 41 runners on the campaign with 29.3% of them ended up crossing the plate. They have compiled 15 saves for the year and have blown 8 out of their 23 chances to save the game. The Mariners relievers have recorded a save rate of 65.2% and have entered the game in 49 save situations. The relievers have a total of 26 holds so far this season (17th in baseball). Mariners relief pitchers have stepped onto the hill with runners on base 38 times in addition to having 66 appearances in high leverage situations.

The Mariners have converted 69.3% of balls in play into outs out of 3,705 innings, which has them sitting 19th in the majors. The San Francisco Giants have earned a total of 1,235 putouts at this point in the season, as well as 408 assists and 19 errors. Their fielding percentage is holding at .989 which has them ranked 6th in pro baseball, and have 33 double plays.

Diaz has taken the ball for 46 frames and has accumulated 33 K's in his MLB career. His ERA is 4.69 (24 earned runs allowed) and his career WHIP is 1.714. He has surrendered 52 hits (10.2 hits per nine innings) and has 27 walks. Diaz (2-2 career win-loss record) has earned a FIP of 4.62 and he has faced 219 hitters in the major leagues.

The Chicago White Sox hold an OBP of .288 in addition to a batting average of .217 on the year. They have been called out on strikes on 397 instances (12th in the league) and have tallied 330 hits. Chicago has compiled 37 home runs on the year to go along with 152 RBIs. The White Sox hold a team slugging % of .331 and they are scoring 3.34 runs per game (27th in MLB). They have hit 61 doubles, while walking 146 times and putting up 157 runs.

The White Sox have a WHIP of 1.413 with a FIP of 4.57 as a squad so far this year. They rank 19th in baseball as a staff in total hits given up with 391. The Chicago pitching staff have conceded 210 runs on the campaign while having an ERA of 4.23 (189 earned runs surrendered). Their K/BB ratio comes in at 7.50 (336 strikeouts vs 177 free passes). They have given up 50 long balls and they relinquish 4.70 runs per 9 innings (22nd in the league).

Chicago has had bullpen pitchers take the mound in 10 save opportunities and they have earned 3 saves. They rank 30th in the league with a save rate of 30.0%, and they have dispatched 154 bullpen pitchers onto the field so far this season. Their bullpen pitchers have stepped onto the hill 38 times in high leverage situations and on 48 occasions with base runners. Chicago relief pitchers have an inherited score percentage of 33.3% out of their 69 inherited base runners. With 30 save situations, the White Sox have 20 holds in addition to 7 blown saves.

In 3,621 innings on the field, the White Sox have accumulated a defensive efficiency of 69.2% (20th in the majors). The Chicago White Sox have turned 38 double plays and own a fielding percentage of .979 (28th in baseball). The White Sox have accrued 377 assists, 34 errors and have earned 1,207 putouts for the year.

In his pro baseball career, Wilson has surrendered 476 base knocks while he has accumulated 324 strikeouts in 446 frames. He has conceded a total of 234 earned runs while earning a WHIP of 1.394 and being the owner of a FIP of 4.6. He has a K/BB ratio of 2.22 and he has faced 1,939 opposing batters in his pro baseball career. Wilson (20-23 career win-loss record) holds a 4.72 ERA while surrendering 9.6 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Chicago (+106)

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