Seattle Mariners vs Kansas City Royals Prediction, 9/16/2025 MLB Picks, Best Bets & Odds
Game: Seattle Mariners vs Kansas City Royals
Date: Tuesday, September 16, 2025
Location: Kauffman Stadium in Kansas City, MO
TV: FanDuel Sports Network Kansas City
Odds/Point Spread: Seattle (-145) Kansas City (+125)
Kauffman Stadium is where the Kansas City Royals (75-75) will try to defeat the Seattle Mariners (82-68) on Tuesday. The odds on this game have the Mariners at -145 while the Royals are priced at +125. The over/under has been set at 9. The starting pitchers are Logan Gilbert and Michael Wacha.


As a team, the Seattle Mariners are knocking in 4.7 runs per game, which is 10th in MLB. They have earned a total of 705 runs scored and have an on-base percentage of .320. The Mariners have accumulated 215 doubles as a unit and have hit 216 baseballs out of the park. They have compiled 676 runs batted in and 1,242 base knocks for the year, and their batting average sits at .244. Seattle is slugging .416 and have struck out 1,329 times, while being walked on 509 occasions.
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The Mariners hold a team earned run average of 3.91 for the season (14th in MLB), and the staff has rung up 1,315 batters. Mariners pitchers have relinquished 179 long balls in addition to 654 total runs (17th in baseball). Their pitching staff has walked 431 opposing batters and their FIP is 4.03 as a squad on the season. Seattle has relinquished 1,244 base knocks (8.3 per 9 innings) as well as 589 earned runs. They have accumulated a K/BB ratio of 3.05 and their pitching staff sits with a WHIP of 1.24.
The Mariners bullpen have recorded a save percentage of 62.5% and stepped onto the hill in 149 save situations. The bullpen pitchers have inherited 134 runners on the campaign with 25.4% of them earned a run for their team. Mariners pitchers have come into the game with runners on base 124 times in addition to having 205 appearances in high leverage situations. The Mariners have sent 508 relievers to the mound over the course of the season. The relievers have a total of 85 holds so far this season (13th in the league). They have tallied 40 saves for the season and have missed out on 24 out of their 64 save chances.
The Mariners have converted 70.2% of balls hit into play into outs in their 12,201 innings on the field, ranking them 13th in professional baseball. The San Francisco Giants have accounted for 4,067 putouts at this point in the season, as well as 1,260 assists and 63 errors. Their fielding percentage is currently at .988 which has them ranked 6th in the majors, and have a total of 110 double plays.
Gilbert has taken the hill for 818 frames and has earned 870 K's thus far in his career. Gilbert (45-36 record in his career) sits with a FIP of 3.54 and he has gone up against 3,309 hitters in the major leagues. His earned run average is 3.60 (327 ER's allowed) and he has a career WHIP of 1.060. He has conceded 689 base knocks (7.6 hits per 9 innings) and has 178 walks.
The Royals hold a slugging percentage of .391 and they have an average of 3.85 runs per contest (28th in baseball). They have hit 263 doubles, while taking a walk 397 times as well as scoring 577 runs. Kansas City has a total of 144 home runs on the season as well as 567 RBIs. They have struck out on 1,015 instances (29th in MLB) and have 1,219 hits. The Kansas City Royals have accounted for an on-base percentage of .305 and a batting average of .244 for the year.
The Royals hold a team WHIP of 1.253 with a FIP of 4.00 as a pitching staff this season. They come in at 14th in MLB as a pitching staff in total hits surrendered with 1,221. The Kansas City pitching staff have conceded 589 runs on the season and come in with a team ERA of 3.72 (550 earned runs given up). Their K/BB ratio sits at 7.90 (1,174 strikeouts vs 446 free passes). They have given up 155 home runs and they give up 3.99 runs per 9 innings (4th in baseball).
Kansas City relief pitchers have an inherited score percentage of 26.7% out of their 206 inherited runners. Their bullpen pitchers have stepped onto the hill 161 times in high leverage situations in addition to 151 occasions with runners on. With 142 save situations, the Royals have recorded 78 holds in addition to 19 blown saves. They are ranked 4th in the league with a save percentage of 69.8%, and they have dispatched 505 relief pitchers to the hill for the year. Kansas City has called on relief pitchers to step onto the mound in 63 save chances and they have earned 44 saves.
In their 11,970 innings played, the Royals have earned a defensive efficiency of 70.6% (9th in MLB). The Kansas City Royals have turned 120 double plays and have a fielding percentage of .989 (4th in MLB). The Royals have 1,326 assists, 57 errors and are sitting with 3,990 putouts this year.
Wacha (110-73 career mark) is the owner of a 3.85 earned run average while allowing 8.7 hits per 9 innings. He has a strikeout to walk ratio of 2.82 and he has faced 6,783 opposing hitters so far in his MLB career. He has given up a total of 690 earned runs while holding a WHIP of 1.271 and being the owner of a FIP of 3.8. Thus far in his career, Wacha has allowed 1,552 base knocks while accumulating 1,407 strikeouts in 1,613 frames.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Kansas City (+125)
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Additional Resources:
Kansas City Royals - Twitter
Seattle Mariners - Twitter