St. Louis Cardinals vs Baltimore Orioles Prediction, 5/26/2025 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Baltimore Orioles

Date: Monday, May 26, 2025

Location: Oriole Park at Camden Yards in Baltimore, MD

TV: MASN

Odds/Point Spread: St. Louis (-130) Baltimore (+110)

Oriole Park at Camden Yards is the site where the Baltimore Orioles (16-32) will meet the St. Louis Cardinals (27-23) on Monday. The odds on this game have the Cardinals at -130 while the Orioles open at +110. The betting total comes in at 8. The men taking the mound are Erick Fedde and Tomoyuki Sugano.

St. Louis has a slugging % of .404 and have struck out 381 times, while taking a walk on 167 occasions. They have accrued 226 RBI's and 450 base knocks on the campaign, while their team batting average sits at .263. The Cardinals have accumulated 97 doubles as a unit and have knocked 47 balls out of the park. They have 240 runs while having a team on-base percentage of .334. As a unit, the St. Louis Cardinals are scoring 4.8 runs per game, which ranks them 7th in MLB.

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The Cardinals have a team earned run average of 3.73 so far this season (12th in the league), and their staff has rung up 354 hitters. Cardinals pitchers have allowed 37 long balls in addition to 200 runs (13th in the league). Their pitching staff has walked 145 opposing hitters and their FIP is 3.65 as a team this year. St. Louis has given up 394 hits (8.0 per 9 innings) in addition to 184 earned runs. They have a strikeout to walk ratio of 2.44 and the pitching staff has earned a collective WHIP of 1.22.

Cardinals relief pitchers have stepped onto the hill with players on base 47 times as well as having 61 appearances in high leverage situations. The relievers have notched 33 holds on the year (8th in the league). The Cardinals bullpen have accumulated a save percentage of 63.2% and have entered the game in 53 save situations. They have accumulated 12 saves this year and have missed out on 7 of their 19 save chances. The bullpen pitchers have inherited 64 base runners for the season with 37.5% of those players crossed the plate. The Cardinals have sent 148 relievers to the hill for the season.

The St. Louis Cardinals have a tally of 1,331 putouts at this point in the season, as well as 497 assists and 17 errors. Their fielding percentage is at .991 which puts them in 1st in pro baseball, and they have turned 35 double plays. The Cardinals have converted 71.6% of balls in play into outs out of their 3,993 innings on the field, which has them sitting 7th in professional baseball.

Fedde (33-45 career mark) has earned a FIP of 4.66 while facing 2,974 opposing batters in the major leagues. He has given up 703 base hits (9.2 hits per nine innings) and has had 268 walks. His ERA is 4.73 (362 earned runs allowed) and his WHIP is 1.411. Fedde has pitched in 688 innings and has 540 K's in his career.

The Baltimore Orioles have earned an on-base percentage of .299 and a team batting average of .232 this year. They have been rung up on 430 instances (9th in MLB) and have accounted for 371 base knocks. Baltimore has hit 56 home runs over the course of the season and 174 RBIs. The Orioles have a team slugging % of .387 and they are recording 3.81 runs per game (25th in baseball). They have tallied 66 doubles, while walking 134 times as well as putting up 183 runs.

The Baltimore pitching staff have allowed 268 runs for the season and come in with a team ERA of 5.45 (253 earned runs relinquished). They have surrendered 76 HR's and they concede 5.77 runs per 9 innings (28th in baseball). The Orioles hold a team WHIP of 1.476 with a FIP of 5.02 as a pitching staff on the season. They have earned a K/BB ratio of 7.90 (365 strikeouts vs 169 walks). They rank 25th in MLB as a staff in total hits surrendered with 448.

Sitting with 42 save situations, the Orioles have 27 holds and 5 blown saves. Baltimore has had relievers step onto the mound in 12 save opportunities and they have come away with 7 saves. Their relief pitchers have come in 39 times in high leverage situations in addition to 58 occasions with base runners. Baltimore bullpen pitchers hold an inherited score percentage of 24.7% out of 73 inherited base runners. They rank 21st in baseball holding a save rate of 58.3%, and they have sent 167 bullpen pitchers to the hill so far this year.

Out of their 3,762 innings on the diamond, the Orioles have a defensive efficiency of 68.1% (23rd in the majors). The Baltimore Orioles have turned 34 double plays and have a fielding percentage of .984 (20th in professional baseball). The Orioles have racked up 438 assists, 27 errors and have earned 1,254 putouts over the course of the season.

During his MLB career, Sugano has allowed 50 base hits while earning 32 strikeouts in 58 innings pitched. Sugano (4-3 record in his career) has earned a 3.09 ERA and has conceded 7.7 hits per 9 innings. He has allowed 20 ER's while holding a WHIP of 1.031 and having a FIP of 3.0. He has a strikeout to walk ratio of 3.20 and he has faced 232 opposing hitters in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take St. Louis (-130)

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