St. Louis Cardinals vs Chicago Cubs Prediction, 7/6/2025 MLB Picks, Best Bets & Odds

Game: St. Louis Cardinals vs Chicago Cubs

Date: Sunday, July 6, 2025

Location: Wrigley Field in Chicago, IL

TV: Marquee

Odds/Point Spread: St. Louis (+102) Chicago (-122)

The Chicago Cubs (51-35) will go up against the St. Louis Cardinals (47-41) at Wrigley Field on Sunday. The odds on this game have the Cardinals at +102 while the Cubs are opening at -122. The total comes in at 9. The pitchers who are expected to start will be Erick Fedde and Matthew Boyd.

St. Louis has a slugging rate of .393 and have been called out on strikes 682 times, while drawing a walk on 276 occasions. They have accumulated 383 RBI's as well as 754 hits for the season, and their average at the plate sits at .253. The Cardinals have accounted for 151 doubles as a unit and have hit 87 balls out of the park. They have accounted for 403 runs scored and hold an OBP of .323. As a team, the St. Louis Cardinals are notching 4.6 runs/g, which is 11th in MLB.

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The Cardinals have an earned run average of 3.94 for the season (17th in the league), and the staff has rung up 640 hitters. Cardinals pitchers have surrendered 73 home runs in addition to 371 runs (17th in the league). Their pitching staff has walked 240 players from the other team and their FIP comes in at 3.68 as a squad on the campaign. St. Louis has relinquished 741 base knocks (8.5 per 9 innings) in addition to 342 earned runs. They have accrued a K/BB ratio of 2.67 and the pitching staff sits with a WHIP of 1.26.

The Cardinals have sent 261 relievers to the mound for the year. The relief pitchers have inherited 114 base runners on the year and 34.2% of those runners earned a run for their team. They have 21 saves on the campaign and have missed out on 12 out of their 33 chances to get a save. The Cardinals bullpen have recorded a save rate of 63.6% and have entered the game in 86 save situations. The relief pitchers have a total of 50 holds this year (13th in the league). Cardinals bullpen pitchers have entered the game with opponents on base 86 times and also have had 95 appearances in high leverage situations.

The St. Louis Cardinals have notched a total of 2,345 putouts this year, as well as 855 assists and 32 errors. Their fielding percentage is holding at .990 which has them ranked 2nd in the majors, and have accumulated 64 double plays. The Cardinals have converted 70.2% of balls hit into play into outs out of 7,035 innings on the field, which has them sitting at 15th in the majors.

Fedde has thrown 723 innings and has earned 563 K's thus far in his career. His earned run average is 4.79 (385 earned runs allowed) and his career WHIP is 1.424. He has surrendered 746 base knocks (9.3 hits per 9 innings) with 284 free passes. Fedde (33-50 career win-loss mark) has earned a FIP of 4.72 and he has faced 3,138 hitters in the majors.

The Chicago Cubs have an OBP of .327 in addition to a team batting average of .257 on the year. They have been rung up on 669 occasions (25th in baseball) and have recorded 764 hits. Chicago has recorded 125 home runs this season to go along with 454 RBIs. The Cubs hold a slugging % of .446 and they score 5.38 runs per outing (2nd in baseball). They have 151 two-baggers, while getting a free base 301 times as well as putting up 463 runs.

The Cubs hold a team WHIP of 1.240 and are the owners of a FIP of 4.20 as a unit on the year. They currently have a strikeout to walk ratio of 7.50 (641 strikeouts against 235 bases on balls). They rank 16th in baseball as a staff in total hits relinquished with 716. They have allowed 103 home runs and they relinquish 4.16 runs per 9 innings (14th in the league). The Chicago pitching staff have yielded 355 runs so far this season while having an ERA of 3.84 (327 earned runs surrendered).

With 89 save situations, the Cubs have 56 holds and also 9 blown saves. Chicago has had relief pitchers enter the contest in 30 save chances and they have walked away with 21 saves. Their relievers have taken the field 91 times in high leverage situations in addition to 61 occasions with runners on. Chicago relievers hold an inherited score percentage of 31.7% of 82 inherited runners. They sit at 6th in baseball with a save percentage of 70.0%, and they have sent 286 relievers onto the field over the course of the season.

In their 6,909 innings played, the Cubs are sitting with a defensive efficiency of 71.0% (6th in professional baseball). The Chicago Cubs have turned 73 double plays and have notched a fielding percentage of .988 (7th in the majors). The Cubs have accrued 735 assists, 37 errors and have earned 2,303 putouts this year.

Boyd (54-72 record in his career) is the owner of a 4.63 ERA while giving up 8.8 hits per nine innings. His strikeout to walk ratio is 3.09 and he has gone up against 4,290 opposing hitters in his pro baseball career. He has given up 518 ER's while earning a WHIP of 1.292 and being the owner of a FIP of 4.6. During his MLB career, Boyd has allowed 984 base knocks while accumulating 978 K's in 1,006 innings.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take Chicago (-122) and under 9 runs

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