Tampa Bay Rays vs Chicago Cubs Prediction, 9/13/2025 MLB Picks, Best Bets & Odds
Game: Tampa Bay Rays vs Chicago Cubs
Date: Saturday, September 13, 2025
Location: Wrigley Field in Chicago, IL
TV: Marquee
Odds/Point Spread: Tampa Bay (+102) Chicago (-122)
The Tampa Bay Rays (72-73) are headed to Wrigley Field on Saturday where they will meet the Chicago Cubs (83-63). The moneyline on this game has the Rays at +102 and the Cubs open at -122. The over/under is set at 8. The pitchers who are expected to start are Drew Rasmussen and Colin Rea.


As a squad, the Tampa Bay Rays are knocking in 4.5 runs per game, which has them at 13th in baseball. They have a total of 654 runs scored while holding a team OBP of .314. The Rays have accrued 219 doubles as a team and have knocked 166 baseballs out of the park. They have recorded 622 runs batted in as well as 1,232 base knocks for the season, and their batting average is at .252. Tampa Bay has a slugging percentage of .405 and have been called out on strikes 1,240 times, while drawing a walk on 416 occasions.
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The Rays have compiled a team earned run average of 3.87 for the season (13th in the league), and their staff has rung up 1,271 batters. Rays pitchers have surrendered 187 home runs and also 599 total runs (9th in the league). They have walked 415 players from the other team and their FIP sits at 4.17 as a unit this year. Tampa Bay has yielded 1,134 base knocks (7.9 per 9 innings) as well as 552 earned runs. Their strikeout to walk ratio sits at 3.06 and the pitching staff holds a collective WHIP of 1.21.
The Rays have sent 463 relief pitchers to the mound on the campaign. The relief pitchers have inherited 149 base runners so far this year with 31.5% of them crossed the plate. They have recorded 33 saves on the season and have blown 25 of their 58 save chances. The Rays relief pitchers have accumulated a save rate of 56.9% and have come into the game in 141 save situations. The relievers have a total of 81 holds so far this year (16th in MLB). Rays relief pitchers have gone to the mound with runners on 101 times in addition to having 139 appearances in high leverage situations.
The Tampa Bay Rays have 3,853 putouts for the season, as well as 1,268 assists and 69 errors. Their fielding percentage is holding steady at .987 which has them sitting 12th in baseball, and they have turned 131 double plays. The Rays have turned 70.8% of balls in play into outs in their 11,559 innings, ranking them 6th in the majors.
Rasmussen has thrown 449 frames and has totaled 418 strikeouts during his career. Rasmussen (30-17 career mark) holds a FIP of 2.82 while he has faced 1,792 batters in the major leagues. His ERA is 2.86 (143 ER's allowed) and his career WHIP is 1.057. He has surrendered 362 base knocks (7.2 hits per nine innings) and has had 113 free passes.
Chicago has recorded 196 long balls over the course of the season to go along with 696 runs batted in. They have hit 239 doubles, while getting a free base 500 times as well as notching 713 runs. The Chicago Cubs are sitting with a team on-base percentage of .319 and a team batting average of .248 for the year. The Cubs hold a team slugging percentage of .425 and they are scoring 4.88 runs per outing (8th in the league). They have struck out on 1,140 occasions (26th in MLB) and have tallied 1,230 hits.
The Cubs have a team WHIP of 1.191 and have a FIP of 4.18 as a staff this season. Their K/BB ratio is 7.80 (1,119 strikeouts vs 370 walks). They are sitting at 11th in MLB as a pitching staff in total hits allowed with 1,172. They have given up 179 long balls and they allow 4.12 runs per 9 innings (7th in baseball). The Chicago pitching staff have surrendered 593 runs this year and come in with a team ERA of 3.86 (555 earned runs relinquished).
Sitting with 157 save situations, the Cubs have compiled 99 holds in addition to 17 blown saves. Chicago has called on bullpen pitchers to step onto the hill in 55 save chances and they have walked away with 38 saves. Their bullpen pitchers have stepped onto the hill 146 times in high leverage situations in addition to 94 occasions with runners on. Chicago relievers hold an inherited score rate of 32.8% out of their 131 inherited base runners. They are ranked 4th in baseball with a save rate of 69.1%, and they have sent 474 bullpen pitchers to the hill for the season.
In their 11,655 innings on the field, the Cubs hold a efficiency on defense of 71.6% (3rd in the majors). The Chicago Cubs have gotten 113 double plays and own a fielding percentage of .989 (5th in pro baseball). The Cubs have accrued 1,225 assists, 57 errors and are sitting with 3,885 putouts for the season.
Rea (36-26 career mark) has earned a 4.49 ERA while conceding 8.8 hits per 9 innings. His K/BB ratio is 2.60 and he has gone up against 2,499 batters during his MLB career. He has allowed a total of 293 ER's while earning a WHIP of 1.286 and a FIP of 4.4. During his career, Rea has given up 574 hits while tallying 470 K's in 587 innings pitched.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Tampa Bay (+102)
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Additional Resources:
Chicago Cubs - Twitter
Tampa Bay Rays - Twitter