Toronto Blue Jays vs Kansas City Royals Prediction, 9/21/2025 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Kansas City Royals

Date: Sunday, September 21, 2025

Location: Kauffman Stadium in Kansas City, MO

TV: FanDuel Sports Network Kansas City

Odds/Point Spread: Toronto (-210) Kansas City (+172)

The Toronto Blue Jays (89-64) are on their way to Kauffman Stadium on Sunday where they will take on the Kansas City Royals (76-77). The moneyline on this contest has Toronto at -210 while Kansas City is coming in at +172. The over/under comes in at 8. The pitchers expected to start will be Shane Bieber and Noah Cameron.

The Blue Jays have tallied 279 doubles as a squad and have knocked 180 baseballs out of the park. Toronto is slugging .429 and have struck out 1,039 times, while being walked on 491 occasions. As a squad, the Toronto Blue Jays are compiling 5.0 runs per outing, which is 5th in baseball. They have compiled 732 RBI's as well as 1,398 hits for the year, and their team batting average is .268. They have 758 runs scored while holding a team OBP of .335.

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They have earned a K/BB ratio of 2.79 and their pitching staff has a collective WHIP of 1.26. Blue Jays pitchers have surrendered 199 home runs and also 675 runs (19th in MLB). Toronto has given up 1,225 base hits (8.1 per 9 innings) as well as 622 earned runs. The Blue Jays hold a team earned run average of 4.12 on the season (19th in the league), and their staff has struck out 1,356 hitters. They have walked 486 hitters and their FIP is 4.28 as a squad this season.

Blue Jays relief pitchers have gone to the mound with runners on base 166 times as well as having 153 appearances in high leverage situations. The relief pitchers have a total of 91 holds this season (10th in MLB). The Blue Jays relief pitchers have accumulated a save percentage of 63.5% and have come into the game in 160 save situations. They have accumulated 40 saves this season and have missed out on 23 of 63 save chances. The relief pitchers have inherited 236 base runners on the campaign and 28.8% of them crossed the plate. The Blue Jays have sent 532 relief pitchers to the hill so far this year.

The Toronto Blue Jays have 4,053 putouts over the course of the season, in addition to 1,183 assists and 82 errors. Their fielding percentage is currently at .985 which ranks 20th in baseball, and have earned 109 double plays. The Blue Jays have turned 70.3% of baseballs in play into outs out of 12,159 innings, which ranks them 11th in pro baseball.

Bieber has pitched in 872 innings and has earned 988 punch outs in his career. His ERA is 3.24 (314 earned runs allowed) and he has a WHIP of 1.111. He has given up 777 hits (8.0 hits per 9 innings) and has had 192 walks. Bieber (65-33 record in his career) has a FIP of 3.19 while he has faced 3,528 hitters in the majors.

The Royals hold a slugging % of .392 and they average 3.85 runs per game (28th in MLB). They have notched 268 doubles, while taking a walk 404 times as well as earning 589 runs. Kansas City has tallied 148 home runs so far this year and 579 runs batted in. They have been called out on strikes on 1,034 instances (30th in baseball) and have earned 1,246 hits. The Kansas City Royals have earned an on-base percentage of .306 in addition to a batting average of .244 over the course of the season.

The Kansas City pitching staff have surrendered 608 runs so far this season while holding a team ERA of 3.77 (568 earned runs surrendered). They have allowed 162 home runs and they yield 4.03 runs per 9 innings (4th in the league). The Royals are sitting with a team WHIP of 1.255 in addition to having a FIP of 4.04 as a team so far this year. Their strikeout to walk ratio comes in at 7.90 (1,194 strikeouts against 453 free passes). They are currently ranked 14th in the league as a pitching staff in total hits conceded with 1,250.

Kansas City bullpen pitchers hold an inherited score percentage of 26.9% out of 208 inherited base runners. Their bullpen pitchers have stepped onto the mound 163 times in high leverage situations in addition to 153 occasions with base runners. With 146 save situations, the Royals have earned 80 holds in addition to 20 blown saves. They are ranked 5th in the league holding a save rate of 69.2%, and they have dispatched 518 relievers to the mound on the campaign. Kansas City has had relief pitchers enter the contest in 65 save chances and they have come away with 45 saves.

The Kansas City Royals have turned 124 double plays and have earned a fielding percentage of .989 (4th in MLB). The Royals have recorded 1,348 assists, 58 errors and have accumulated 4,044 putouts so far this year. In 12,132 innings on the diamond, the Royals have accumulated a defensive efficiency of 70.6% (8th in professional baseball).

During his MLB career, Cameron has surrendered 102 hits and he has 103 strikeouts in 127 innings. He has surrendered a total of 42 earned runs while earning a WHIP of 1.094 and being the owner of a FIP of 2.9. He has a K/BB ratio of 2.78 and he has faced 510 hitters in his pro baseball career. Cameron (8-7 record in his career) holds a 2.98 ERA while allowing 7.2 hits per 9 innings.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Kansas City (+172)

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