Toronto Blue Jays vs Tampa Bay Rays Prediction, 9/16/2025 MLB Picks, Best Bets & Odds

Game: Toronto Blue Jays vs Tampa Bay Rays

Date: Tuesday, September 16, 2025

Location: George M. Steinbrenner Field in Tampa, FL

TV: FanDuel Sports Network Sun

Odds/Point Spread: Toronto (-196) Tampa Bay (+162)

The Tampa Bay Rays (73-76) host the Toronto Blue Jays (87-62) at George M. Steinbrenner Field on Tuesday. The moneyline on this contest has the Blue Jays at -196 while the Rays are sitting at +162. The over/under has been set at 8. The men taking the mound will be Jose Berrios and Ryan Pepiot.

As a team, the Toronto Blue Jays are putting up 5.0 runs per game, which is 4th in the league. They have 749 runs and hold an OBP of .338. The Blue Jays have tallied 276 doubles as a unit and have smacked 178 balls out of the park. They have earned 723 RBI's as well as 1,374 base knocks over the course of the season, and their team batting average comes in at .270. Toronto has a slugging percentage of .433 and have struck out 1,008 times, while drawing a walk on 485 occasions.

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The Blue Jays are sitting with a team earned run average of 4.15 for the year (19th in MLB), and the staff has rung up 1,318 batters. Blue Jays pitchers have conceded 197 home runs and 663 runs in total (19th in the league). They have walked 471 players from the other team and their FIP sits at 4.31 as a unit this season. Toronto has given up 1,192 base hits (8.1 per 9 innings) and 610 earned runs. Their strikeout to walk ratio sits at 2.80 and the pitching staff has a collective WHIP of 1.26.

Blue Jays relief pitchers have stepped onto the hill with runners on base 159 times as well as having 146 appearances in high leverage situations. The bullpen have recorded 88 holds this season (11th in the league). The Blue Jays relievers have a save percentage of 62.9% and have stepped onto the mound in 155 save situations. They have recorded 39 saves over the course of the season and have missed out on 23 of their 62 save opportunities. The relief pitchers have inherited 228 base runners over the course of the season and 29.4% of them earned a run for their team. The Blue Jays have dispatched 516 relief pitchers to the mound over the course of the season.

The Toronto Blue Jays have 3,969 putouts over the course of the season, in addition to 1,150 assists and 81 errors. Their fielding percentage is currently at .984 which puts them in 21st in professional baseball, and they have turned 107 double plays. The Blue Jays have turned 70.3% of balls in play into outs in their 11,907 innings on the field, ranking them 11th in MLB.

Berrios has taken the mound for 1,565 innings and has racked up 1,478 K's during his pro baseball career. His ERA is 4.07 (707 earned runs allowed) and he has a WHIP of 1.238. He has surrendered 1,468 base hits (8.4 hits per nine innings) with 469 walks. Berrios (108-82 career record) has earned a FIP of 4.00 and he has faced 6,579 hitters in the majors.

The Rays have a slugging percentage of .405 and they have an average of 4.48 runs per outing (13th in MLB). They have 223 two-baggers, while walking 424 times and earning 667 runs. Tampa Bay has 171 HRs on the year to go along with 635 RBIs. They have struck out on 1,273 occasions (11th in baseball) and have notched a total of 1,267 hits. The Tampa Bay Rays have compiled a team OBP of .313 as well as a batting average of .252 this season.

The Tampa Bay pitching staff have given up 618 runs for the season while holding a team ERA of 3.90 (571 earned runs surrendered). They have yielded 191 homers and they yield 4.22 runs per 9 innings (10th in MLB). The Rays have a team WHIP of 1.216 in addition to having a FIP of 4.18 as a team on the year. They currently have a K/BB ratio of 8.90 (1,304 strikeouts vs 432 bases on balls). They come in at 7th in MLB as a staff in total hits given up with 1,169.

With 143 save situations, the Rays have accrued 81 holds in addition to 26 blown saves. Tampa Bay has had relievers take the mound in 60 save opportunities and they have converted 34 saves. Their relievers have come in 144 times in high leverage situations and on 104 occasions with base runners. Tampa Bay relief pitchers have an inherited score percentage of 31.6% out of 155 inherited base runners. They are ranked 26th in the league with a save percentage of 56.7%, and they have sent 476 relief pitchers to the hill so far this season.

The Tampa Bay Rays have gotten 134 double plays and have a fielding rate of .987 (10th in the majors). The Rays have 1,302 assists, 69 errors and have earned 3,952 putouts this season. In 11,856 innings on the diamond, the Rays have earned a defensive efficiency of 70.7% (7th in MLB).

During his pro baseball career, Pepiot has given up 282 base knocks while accumulating 383 K's in 371 innings. Pepiot (24-19 career record) holds a 3.42 earned run average while conceding 6.8 hits per 9 innings. He has surrendered 141 earned runs while earning a WHIP of 1.129 and a FIP of 3.4. He has a strikeout to walk ratio of 2.80 and he has gone up against 1,512 hitters so far in his pro baseball career.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Toronto (-196)

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