Washington Nationals vs San Diego Padres Prediction, 6/25/2025 MLB Picks, Best Bets & Odds
Game: Washington Nationals vs San Diego Padres
Date: Wednesday, June 25, 2025
Location: Petco Park in San Diego, CA
TV: Padres.TV
Odds/Point Spread: Washington (+162) San Diego (-196)
The San Diego Padres (42-36) are welcoming the Washington Nationals (33-46) at Petco Park on Wednesday. The line on this contest has Washington at +162 and San Diego is coming in at -196. The total comes in at 8. The expected starting pitchers will be MacKenzie Gore and Nick Pivetta.


Washington has a slugging % of .394 and have been called out on strikes 591 times, while drawing a walk on 224 occasions. They have earned 323 RBI's and 640 base knocks this season, and their average at the plate is .243. The Nationals have accounted for 129 two-baggers as a team and have knocked 83 baseballs out of the park. They have racked up 339 runs scored and have an OBP of .309. As a team, the Washington Nationals are recording 4.3 runs per game, which puts them at 15th in the league.
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The Nationals are sitting with a team earned run average of 5.00 on the campaign (28th in MLB), and they have struck out 626 hitters. Nationals pitchers have allowed 95 home runs and 408 total runs (28th in baseball). Their pitching staff has walked 260 opposing players and their FIP is 4.39 as a team so far this year. Washington has given up 702 base knocks (9.1 per 9 innings) in addition to 387 earned runs. They have a K/BB ratio of 2.41 and their pitching staff has a team WHIP of 1.38.
The Nationals relief pitchers have a save rate of 63.3% and have come into the game in 64 save situations. The relief pitchers have inherited 144 runners so far this season with 41.0% of them earned a run for their team. Nationals bullpen pitchers have entered the game with runners on base 83 times in addition to having 61 appearances in high leverage situations. The Nationals have dispatched 268 relievers to the mound this season. The relief pitchers have notched 34 holds over the course of the season (28th in the league). They have accumulated 19 saves over the course of the season and have blown 11 of 30 save chances.
The Washington Nationals have 2,088 putouts so far this season, in addition to 651 assists and 42 errors. Their fielding percentage is at .985 which ranks 23rd in the majors, and have 56 double plays. The Nationals have converted 68.5% of balls in play into outs out of their 6,264 innings, which has them sitting 23rd in baseball.
Gore (24-33 career mark) sits with a FIP of 3.94 and he has faced 2,003 batters during his time in the majors. He has given up 455 base knocks (8.8 hits per 9 innings) with 186 walks. His ERA is 4.00 (207 ER's allowed) and he has a WHIP of 1.378. Gore has taken the mound for 465 innings and has earned 527 K's during his career.
San Diego has tallied 68 long balls so far this season and 307 RBIs. They have hit 116 two-baggers, while taking a walk 245 times and scoring 331 runs. The San Diego Padres hold an on-base percentage of .316 in addition to a team batting average of .249 for the season. The Padres hold a slugging % of .381 and they are recording 4.24 runs per game (18th in the league). They have struck out on 548 occasions (28th in the league) and are sitting with 648 hits.
The San Diego pitching staff have given up 310 runs over the course of the season while holding an ERA of 3.65 (280 earned runs yielded). They have allowed 79 long balls and they relinquish 4.04 runs per 9 innings (10th in MLB). The Padres have a team WHIP of 1.230 with a FIP of 3.87 as a unit so far this season. They currently have a K/BB ratio of 8.80 (676 strikeouts vs 259 bases on balls). They are currently ranked 5th in baseball as a pitching staff in total hits allowed with 590.
San Diego has had bullpen pitchers take the mound in 34 save opportunities and they have come away with 25 saves. They are ranked 4th in the league holding a save percentage of 73.5%, and they have dispatched 275 bullpen pitchers to the hill this year. Their bullpen pitchers have come in 108 times in high leverage situations in addition to 89 occasions with base runners. San Diego bullpen pitchers have an inherited score rate of 34.9% of 126 inherited base runners. With 85 save situations, the Padres have 50 holds and also 9 blown saves.
In their 6,216 innings on the diamond, the Padres have accumulated a efficiency on defense of 71.1% (6th in baseball). The San Diego Padres have turned 56 double plays and hold a fielding percentage of .986 (19th in MLB). The Padres have accrued 591 assists, 39 errors and have a total of 2,072 putouts over the course of the season.
During his pro baseball career, Pivetta has allowed 1,045 base hits while accumulating 1,230 strikeouts in 1,113 innings pitched. He has given up 578 earned runs while holding a WHIP of 1.299 and a FIP of 4.6. His K/BB ratio is 3.07 and he has gone up against 4,725 opposing hitters in his pro baseball career. Pivetta (63-73 career win-loss mark) holds a 4.67 ERA and has allowed 8.4 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Josh Schonwald's Pick: Take Washington (+162)
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Additional Resources:
San Diego Padres - Twitter
Washington Nationals - Twitter