Arizona Diamondbacks vs Milwaukee Brewers Prediction, 4/28/2026 MLB Picks, Best Bets & Odds
Game: Arizona Diamondbacks vs Milwaukee Brewers
Date: Tuesday, April 28, 2026
Location: American Family Field in Milwaukee, WI
TV: Brewers.TV
Odds/Point Spread: Arizona (+150) Milwaukee (-182)
American Family Field is the location where the Milwaukee Brewers (14-13) will go up against the Arizona Diamondbacks (15-12) on Tuesday. The odds on this game have Arizona at +150 while Milwaukee is opening at -182. The betting total comes in at 8. The starting pitchers will be Merrill Kelly and Chad Patrick.

The Diamondbacks have tallied 54 two-baggers as a unit and have knocked 27 baseballs out of the stadium. Arizona is slugging .426 and have been called out on strikes 209 times, while drawing a walk on 70 occasions. As a squad, the Arizona Diamondbacks are putting up 4.9 runs/g, which is 7th in the league. They have 126 RBI's in addition to 230 base knocks this year, while their batting average is at .255. They have notched a total of 132 runs while holding a team on-base percentage of .310.
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They have earned a K/BB ratio of 2.37 and their pitching staff holds a WHIP of 1.32. Diamondbacks pitchers have surrendered 37 home runs and 137 runs in total (23rd in MLB). Arizona has allowed 232 hits (8.7 per 9 innings) in addition to 121 earned runs. The Diamondbacks have a team earned run average of 4.53 on the campaign (24th in MLB), and the staff has rung up 204 hitters. Their pitching staff has walked 86 opposing batters and their FIP is 4.62 as a squad so far this year.
The Diamondbacks have dispatched 97 relievers to the hill on the season. The relievers have inherited 35 runners this year and 31.4% of those runners earned a run for their team. The bullpen have recorded 23 holds on the season (1st in MLB). Diamondbacks pitchers have stepped onto the hill with opponents on base 25 times as well as having 42 appearances in high leverage situations. They have earned 9 saves on the season and have blown 6 out of their 15 save chances. The Diamondbacks relievers have compiled a save rate of 60.0% and have entered the game in 39 save situations.
The Diamondbacks have converted 70.6% of balls hit into play into outs in their 2,163 innings on the field, ranking them 14th in the majors. The Arizona Diamondbacks have amassed 721 putouts so far this season, as well as 239 assists and 15 errors. Their fielding percentage is holding at .985 which puts them in 16th in baseball, and they have turned 18 double plays.
Kelly has taken the ball for 1,017 frames and has earned 919 punch outs so far in his pro baseball career. His earned run average is 3.82 (432 ER's allowed) and he has a career WHIP of 1.208. He has allowed 922 base knocks (8.2 hits per nine innings) and has 307 walks. Kelly (66-54 career win-loss mark) sits with a FIP of 3.76 and he has gone up against 4,193 batters in the major leagues.
The Milwaukee Brewers have recorded a team on-base percentage of .329 and a team batting average of .231 for the year. They have struck out on 225 occasions (20th in the league) and have totaled 206 hits. Milwaukee has tallied 19 home runs this year as well as 127 runs batted in. The Brewers hold a slugging % of .349 and they are earning 4.89 runs per game (8th in baseball). They have recorded 40 doubles, while getting a free base 126 times and racking up 132 runs.
The Milwaukee pitching staff have conceded 113 runs for the season and come in with a team ERA of 3.82 (102 earned runs conceded). They have surrendered 24 homers and they surrender 4.24 runs per 9 innings (10th in the league). The Brewers hold a team WHIP of 1.299 and have a FIP of 3.73 as a pitching staff on the season. Their strikeout to walk ratio comes in at 9.40 (250 strikeouts vs 100 bases on balls). They come in at 8th in MLB as a staff in total hits given up with 212.
They rank 16th in baseball holding a save rate of 61.5%, and they have dispatched 92 bullpen pitchers to the mound for the season. Their relievers have stepped onto the mound 33 times in high leverage situations in addition to 26 occasions with base runners. Sitting with 29 save situations, the Brewers have 16 holds and 5 blown saves. Milwaukee has had relievers enter the game in 13 save opportunities and they have walked away with 8 saves. Milwaukee bullpen pitchers have an inherited score percentage of 42.9% out of 42 inherited runners.
The Milwaukee Brewers have gotten 21 double plays and hold a fielding percentage of .987 (11th in baseball). The Brewers have 229 assists, 13 errors and have earned 721 putouts for the year. In their 2,163 innings on the diamond, the Brewers have a efficiency on defense of 69.0% (21st in baseball).
So far in his pro baseball career, Patrick has conceded 134 base knocks while accumulating 138 strikeouts in 142 innings. He has allowed 53 earned runs while holding a WHIP of 1.280 and a FIP of 3.3. He has a K/BB ratio of 2.88 and he has faced 597 batters so far in his pro baseball career. Patrick (4-9 career mark) has a 3.35 earned run average while giving up 8.5 hits per 9 innings.
Who will win tonight's MLB game against the spread or moneyline?
Guy Bruhn's Pick: Take Arizona (+150)
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Additional Resources:
Milwaukee Brewers - Twitter
Arizona Diamondbacks - Twitter
