Arizona Diamondbacks vs San Diego Padres Prediction, 9/27/2026 MLB Picks, Best Bets & Odds

Game: Arizona Diamondbacks vs San Diego Padres

Date: Sunday, September 27, 2026

Location: Petco Park in San Diego, CA

TV: Padres.TV

Odds/Point Spread: Arizona (+132) San Diego (-160)

The Arizona Diamondbacks (85-74) are on their way to Petco Park on Sunday where they will take on the San Diego Padres (89-70). The line on this matchup has the Diamondbacks at +132 and the Padres are sitting at -160. The total is 8.5. The pitchers who are expected to start will be Michael Soroka and Michael King.

Arizona has a slugging rate of .402 and have been called out on strikes 1,175 times, while being walked on 526 occasions. They have tallied 686 runs batted in and 1,315 hits on the year, and their team batting average comes in at .246. The Diamondbacks have accumulated 265 two-baggers as a squad and have smacked 162 balls out of the stadium. They have a total of 717 runs scored while having a team OBP of .317. As a unit, the Arizona Diamondbacks are putting up 4.5 runs per contest, which puts them at 12th in MLB.

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Their strikeout to walk ratio is 2.37 and their pitching staff has a collective WHIP of 1.27. Diamondbacks pitchers have conceded 183 long balls and also 707 total runs (15th in the league). Arizona has allowed 1,334 base hits (8.5 per 9 innings) and 646 earned runs. The Diamondbacks have compiled a team ERA of 4.10 on the campaign (13th in the league), and the staff has struck out 1,118 batters. They have walked 471 opposing batters and their FIP comes in at 4.33 as a squad on the season.

Diamondbacks bullpen pitchers have stepped onto the hill with opponents on base 140 times as well as having 170 appearances in high leverage situations. The relief pitchers have accumulated 84 holds so far this year (15th in the league). The Diamondbacks relievers have accumulated a save rate of 67.9% and have entered the game in 141 save situations. They have recorded 38 saves for the season and have missed out on 18 out of their 56 save chances. The relief pitchers have inherited 202 base runners on the season and 26.7% of those players crossing home plate. The Diamondbacks have dispatched 536 relievers to the hill on the campaign.

The Arizona Diamondbacks have a total of 4,251 putouts over the course of the season, in addition to 1,368 assists and 64 errors. Their fielding rate sits at .989 which has them ranked 3rd in MLB, and have accumulated 135 double plays. The Diamondbacks have transformed 71.3% of balls in play into outs in their 12,753 innings on the diamond, which has them sitting 6th in professional baseball.

Soroka has thrown 526 innings and has accumulated 489 punch outs during his career. Soroka (29-31 career mark) sits with a FIP of 3.69 while facing 2,196 batters during his time in the major leagues. His earned run average is 3.75 (219 ER's allowed) and he has a WHIP of 1.195. He has conceded 462 base hits (7.9 hits per nine innings) and has had 167 free passes.

The Padres hold a slugging percentage of .397 and they score 4.40 runs per outing (19th in baseball). They have tallied 230 two-baggers, while getting a free base 542 times and putting up 699 runs. San Diego has accounted for 180 home runs on the season as well as 673 RBIs. They have struck out on 1,288 occasions (21st in MLB) and have recorded 1,280 base hits. The San Diego Padres hold an OBP of .318 in addition to a team batting average of .243 for the year.

The San Diego pitching staff have relinquished 659 runs on the season and come in with a team ERA of 3.93 (615 earned runs conceded). They have yielded 176 homers and they concede 4.21 runs per 9 innings (9th in MLB). The Padres are sitting with a team WHIP of 1.289 with a FIP of 4.16 as a staff on the year. Their K/BB ratio comes in at 8.30 (1,295 strikeouts against 539 free passes). They come in at 13th in the league as a staff in total hits allowed with 1,278.

They are ranked 7th in the league holding a save rate of 71.6%, and they have sent 540 relief pitchers onto the diamond on the year. Their relief pitchers have come in 185 times in high leverage situations in addition to 152 occasions with runners on. Sitting with 177 save situations, the Padres have accumulated 105 holds and also 19 blown saves. San Diego has had bullpen pitchers enter the contest in 67 save chances and they have earned 48 saves. San Diego relief pitchers hold an inherited score rate of 31.2% out of 247 inherited base runners.

The San Diego Padres have turned 128 double plays and own a fielding percentage of .989 (2nd in baseball). The Padres have accrued 1,401 assists, 63 errors and have accounted for 4,228 putouts this season. In 12,684 innings played, the Padres have earned a defensive efficiency of 70.6% (10th in baseball).

King (43-39 career record) holds a 3.23 earned run average and has allowed 7.5 hits per 9 innings. He has a K/BB ratio of 2.97 and he has faced 2,826 hitters so far in his career. He has conceded 244 ER's while earning a WHIP of 1.190 and a FIP of 3.2. In his MLB career, King has allowed 566 hits while earning 718 strikeouts in 679 frames.

Who will win tonight's MLB game against the spread or moneyline?

Josh Schonwald's Pick: Take Arizona (+132)

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