Baltimore Orioles vs Cleveland Guardians Prediction, 4/17/2026 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs Cleveland Guardians

Date: Friday, April 17, 2026

Location: Progressive Field in Cleveland, OH

TV: MLB.TV

Odds/Point Spread: Baltimore (+106) Cleveland (-128)

Progressive Field is the site where the Cleveland Guardians (10-9) will try to beat the Baltimore Orioles (9-9) on Friday. The moneyline on this game has Baltimore at +106 while Cleveland is at -128. The over/under is set at 8.5. The expected starting pitchers are Chris Bassitt and Tanner Bibee.

Baltimore owns a slugging percentage of .393 and have been called out on strikes 162 times, while drawing a walk on 75 occasions. They have accumulated 76 RBI's in addition to 146 hits on the campaign, and their team batting average is sitting at .245. The Orioles have accrued 35 two-baggers as a unit and have smacked 17 baseballs out of the park. They have accounted for 77 runs and hold an on-base percentage of .334. As a unit, the Baltimore Orioles are knocking in 4.3 runs per game, which ranks them 16th in baseball.

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They have a K/BB ratio of 2.69 and their pitching staff holds a WHIP of 1.34. Orioles pitchers have yielded 17 home runs and also 78 runs in total (13th in baseball). Baltimore has allowed 155 hits (8.7 per 9 innings) as well as 71 earned runs. The Orioles are sitting with a team ERA of 3.99 for the year (14th in MLB), and their staff has rung up 159 batters. Their pitching staff has walked 59 opposing players and their FIP is 3.84 as a unit on the year.

The Orioles relief pitchers have earned a save rate of 77.8% and have entered the game in 25 save situations. They have accumulated 7 saves this year and have blown 2 of their 9 save opportunities. The relief pitchers have inherited 18 base runners on the year and 0.0% of those players earned a run for their team. Orioles relief pitchers have stepped onto the hill with runners on 13 times in addition to having 23 appearances in high leverage situations. The Orioles have dispatched 62 relievers to the mound this season. The bullpen have a total of 16 holds for the season (5th in the league).

The Atlanta Braves have notched a total of 481 putouts so far this season, as well as 158 assists and 10 errors. Their fielding rate is holding at .985 which ranks 20th in baseball, and they have turned 17 double plays. The Orioles have converted 67.5% of balls hit into play into outs out of their 1,443 innings, which has them sitting at 27th in pro baseball.

Bassitt has taken the mound for 1,289 innings and has earned 1,196 strikeouts so far in his career. Bassitt (83-67 career mark) sits with a FIP of 3.63 and he has faced 5,471 batters in the major leagues. His earned run average is 3.69 (528 ER's allowed) and he has a career WHIP of 1.256. He has conceded 1,203 base knocks (8.4 hits per 9 innings) and has 416 free passes.

Cleveland has compiled 19 home runs on the year to go along with 70 RBIs. They have tallied 38 two-baggers, while taking a walk 69 times as well as putting up 75 runs. The Cleveland Guardians have compiled a team OBP of .314 and a team batting average of .229 this season. The Guardians have a slugging percentage of .383 and they earn 3.95 runs per game (24th in the league). They have struck out on 143 occasions (23rd in baseball) and have recorded 142 hits.

The Cleveland pitching staff have given up 81 runs for the year while holding a team ERA of 4.06 (75 earned runs conceded). They have yielded 24 HR's and they relinquish 4.39 runs per 9 innings (14th in baseball). The Guardians hold a team WHIP of 1.318 in addition to having a FIP of 4.28 as a unit this season. Their strikeout to walk ratio is 9.80 (181 strikeouts vs 72 free passes). They come in at 20th in MLB as a pitching staff in total hits relinquished with 147.

They rank 11th in baseball with a save rate of 71.4%, and they have dispatched 62 bullpen pitchers onto the diamond on the year. Their relief pitchers have come in 21 times in high leverage situations and also on 18 occasions with base runners. Sitting with 19 save situations, the Guardians have 12 holds and also 2 blown saves. Cleveland has called on bullpen pitchers to step onto the hill in 7 save opportunities and they have earned 5 saves. Cleveland relief pitchers have an inherited score rate of 21.4% out of 28 inherited runners.

The Cleveland Guardians have gotten 17 double plays and have a fielding percentage of .991 (5th in the majors). The Guardians have racked up 133 assists, 6 errors and are sitting with 499 putouts this year. In their 1,497 innings played, the Guardians have accumulated a efficiency on defense of 70.0% (17th in the majors).

Bibee (34-25 win-loss mark in his career) has earned a 3.71 ERA while allowing 8.1 hits per nine innings. He has a K/BB ratio of 3.41 and he has faced 2,139 opposing batters thus far in his career. He has allowed 213 earned runs while holding a WHIP of 1.192 and a FIP of 3.7. During his career, Bibee has given up 466 hits while totaling 508 strikeouts in 516 frames.

Who will win tonight's MLB game against the spread or moneyline?

Guy Bruhn's Pick: Take Cleveland (-128)

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