Baltimore Orioles vs New York Yankees Prediction, 9/25/2026 MLB Picks, Best Bets & Odds

Game: Baltimore Orioles vs New York Yankees

Date: Friday, September 25, 2026

Location: Yankee Stadium in Bronx, NY

TV: YES

Odds/Point Spread: Baltimore (+102) New York (-122)

The Baltimore Orioles (76-81) are en route to Yankee Stadium on Friday where they will attempt to beat the New York Yankees (90-67). The moneyline on this matchup has Baltimore at +102 while New York is at -122. The betting total comes in at 8. The pitchers taking the mound will be Trevor Rogers and Will Warren.

As a squad, the Baltimore Orioles are notching 4.4 runs per game, which has them at 17th in MLB. They have earned 697 runs and hold an on-base percentage of .314. The Orioles have compiled 229 two-baggers as a unit and have hit 192 baseballs out of the park. They have accrued 672 runs batted in and 1,224 hits this season, and their team batting average comes in at .234. Baltimore has a slugging percentage of .395 and have been rung up 1,474 times, while taking a walk on 571 occasions.

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The Orioles have compiled a team ERA of 4.11 for the season (13th in the league), and the staff has rung up 1,269 batters. Orioles pitchers have given up 168 home runs and 727 total runs (21st in MLB). They have walked 525 opposing batters and their FIP sits at 4.08 as a team for the season. Baltimore has relinquished 1,353 base knocks (8.7 per 9 innings) and 640 earned runs. They have earned a K/BB ratio of 2.42 and their pitching staff holds a collective WHIP of 1.34.

The Orioles bullpen have a save rate of 67.2% and have come into the game in 150 save situations. They have compiled 45 saves for the year and have blown 22 of their 67 save opportunities. The relievers have inherited 221 runners over the course of the season and 26.2% of them crossing the plate. Orioles pitchers have gone to the mound with opponents on base 162 times in addition to having 169 appearances in high leverage situations. The Orioles have dispatched 528 relief pitchers to the hill over the course of the season. The bullpen have a total of 80 holds for the season (20th in the league).

The Orioles have converted 68.9% of balls in play into outs out of 12,612 innings on the diamond, which has them ranked 27th in pro baseball. The Baltimore Orioles have amassed 4,204 putouts on the campaign, as well as 1,341 assists and 92 errors. Their fielding rate is holding steady at .984 which puts them in 23rd in baseball, and have earned 119 double plays.

Rogers (34-48 career win-loss record) has a FIP of 3.83 while he has gone up against 2,903 batters during his time in the major leagues. He has surrendered 638 hits (8.4 hits per nine innings) with 234 free passes. His earned run average is 3.89 (296 ER's allowed) and his WHIP is 1.273. Rogers has taken the hill for 685 frames and has earned 674 strikeouts in his pro baseball career.

The Yankees hold a slugging percentage of .408 and they average 4.56 runs per contest (9th in the league). They have 218 two-baggers, while getting a free base 559 times and recording 716 runs. New York has accumulated 217 home runs over the course of the season to go along with 684 RBIs. They have struck out on 1,439 instances (6th in the league) and have a total of 1,214 base hits. The New York Yankees hold a team on-base percentage of .310 as well as a batting average of .234 so far this season.

The New York pitching staff have surrendered 582 runs on the season while having a team ERA of 3.22 (502 earned runs surrendered). They have given up 159 home runs and they surrender 3.73 runs per 9 innings (1st in baseball). The Yankees have a WHIP of 1.162 and have a FIP of 3.69 as a unit on the campaign. Their K/BB ratio comes in at 9.00 (1,404 strikeouts vs 468 walks). They rank 3rd in baseball as a pitching staff in total hits conceded with 1,165.

They are ranked 17th in baseball holding a save percentage of 61.6%, and they have sent 516 relief pitchers to the hill so far this year. Their bullpen pitchers have stepped onto the mound 174 times in high leverage situations in addition to 186 occasions with runners on. Sitting with 162 save situations, the Yankees have recorded 86 holds in addition to 28 blown saves. New York has had relief pitchers enter the game in 73 save chances and they have come away with 45 saves. New York relief pitchers have an inherited score percentage of 22.6% out of their 266 inherited runners.

The New York Yankees have turned 123 double plays and hold a fielding percentage of .984 (22nd in professional baseball). The Yankees have racked up 1,366 assists, 92 errors and have 4,216 putouts so far this year. In 12,648 innings played, the Yankees have a efficiency on defense of 71.3% (5th in the majors).

Warren (19-17 career record) has earned a 4.65 earned run average while allowing 9.3 hits per 9 innings. His strikeout to walk ratio is 2.72 and he has faced 1,483 batters during his career. He has allowed 174 earned runs while earning a WHIP of 1.412 and a FIP of 4.6. During his MLB career, Warren has allowed 347 base hits while tallying 351 strikeouts in 337 innings pitched.

Who will win tonight's MLB game against the spread or moneyline?

Parlay's Pundit's Pick: Take New York (-122) and under 8 runs

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