Boston Red Sox vs Detroit Tigers Prediction, 5/4/2026 MLB Picks, Best Bets & Odds

Game: Boston Red Sox vs Detroit Tigers

Date: Monday, May 4, 2026

Location: Comerica Park in Detroit, MI

TV: Detroit SportsNet

Odds/Point Spread: Boston (-182) Detroit (+150)

The Detroit Tigers (17-17) will take on the Boston Red Sox (13-20) at Comerica Park on Monday. The moneyline on this matchup has Boston at -182 while Detroit is coming in at +150. The betting total comes in at 9. The starting pitchers will be Payton Tolle and Tarik Skubal.

Boston has a slugging % of .351 and have struck out 269 times, while taking a walk on 110 occasions. They have compiled 124 runs batted in in addition to 258 base knocks this year, while their team batting average is at .235. The Red Sox have recorded 54 doubles as a unit and have hit 22 baseballs out of the park. They are sitting with 129 runs scored while holding a team on-base percentage of .313. As a team, the Boston Red Sox are putting up 3.9 runs per game, which puts them at 26th in baseball.

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They have a K/BB ratio of 2.38 and the pitching staff holds a collective WHIP of 1.33. Red Sox pitchers have surrendered 44 home runs in addition to 146 runs (14th in baseball). Boston has conceded 276 base hits (8.6 per 9 innings) in addition to 138 earned runs. The Red Sox have an earned run average of 4.29 so far this season (17th in baseball), and the staff has struck out 259 hitters. Their pitching staff has walked 109 opposing hitters and their FIP sits at 4.62 as a unit on the campaign.

The Red Sox bullpen have accumulated a save rate of 60.0% and have come into the game in 27 save situations. They have accumulated 6 saves for the year and have blown 4 of their 10 save opportunities. The relief pitchers have inherited 44 runners over the course of the season and 34.1% of those runners ended up crossing the plate. Red Sox pitchers have gone to the mound with runners on base 29 times and also have had 26 appearances in high leverage situations. The Red Sox have sent 100 relief pitchers to the mound over the course of the season. The relief pitchers have accumulated 17 holds on the campaign (19th in baseball).

The Red Sox have turned 70.2% of balls hit into play into outs in their 2,604 innings on the field, which has them sitting 13th in baseball. The Boston Red Sox have a tally of 868 putouts on the campaign, in addition to 303 assists and 16 errors. Their fielding percentage sits at .987 which puts them in 12th in the majors, and have accumulated 25 double plays.

Tolle has taken the ball for 26 frames and has 34 K's during his MLB career. His earned run average is 5.13 (15 ER's allowed) and he has a career WHIP of 1.407. He has allowed 24 base hits (8.2 hits per nine innings) and has 13 free passes. Tolle (0-2 career win-loss mark) has a FIP of 5.06 and he has gone up against 116 opposing hitters in the majors.

The Detroit Tigers have an on-base percentage of .333 and a team batting average of .251 for the season. They have been rung up on 275 instances (15th in baseball) and have recorded 285 hits. Detroit has 34 HRs on the campaign and 144 runs batted in. The Tigers have a team slugging % of .406 and they score 4.44 runs per contest (15th in MLB). They have tallied 63 doubles, while getting a free base 132 times and putting up 151 runs.

The Detroit pitching staff have given up 139 runs so far this year and come in with a team ERA of 3.90 (127 earned runs yielded). They have allowed 28 homers and they allow 4.27 runs per 9 innings (9th in MLB). The Tigers hold a team WHIP of 1.317 with a FIP of 3.84 as a staff this year. Their strikeout to walk ratio sits at 8.60 (279 strikeouts vs 120 free passes). They have a ranking of 15th in MLB as a pitching staff in total hits relinquished with 266.

They rank 16th in the league with a save percentage of 61.5%, and they have dispatched 97 relievers onto the field so far this year. Their bullpen pitchers have stepped onto the mound 28 times in high leverage situations and also on 39 occasions with runners on. With 28 save situations, the Tigers have compiled 14 holds in addition to 5 blown saves. Detroit has had relief pitchers step onto the mound in 13 save chances and they have walked away with 8 saves. Detroit relievers have an inherited score percentage of 37.5% of 64 inherited runners.

In their 2,640 innings on the field, the Tigers hold a efficiency on defense of 69.4% (20th in MLB). The Detroit Tigers have gotten 29 double plays and have a fielding percentage of .986 (18th in baseball). The Tigers have accrued 284 assists, 17 errors and have accounted for 880 putouts for the year.

So far in his pro baseball career, Skubal has surrendered 649 base hits while accumulating 934 strikeouts in 809 innings pitched. He has conceded 275 earned runs while holding a WHIP of 1.022 and being the owner of a FIP of 3.0. He has a strikeout to walk ratio of 5.25 and he has gone up against 3,222 batters during his MLB career. Skubal (57-39 mark in his career) holds a 3.06 earned run average and has surrendered 7.2 hits per nine innings.

Who will win tonight's MLB game against the spread or moneyline?

Tony Sink's Pick: Take Boston (-182)

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